The Philadelphia Eagles and Dallas Cowboys face off on Christmas Eve with the former on the brink of claiming the NFC East title.
Having compiled a 13-1 record across their first 14 games, the Eagles are three games ahead of the Cowboys in the division.
They will claim the title from the Cowboys with victory in Dallas but face the challenge of sweeping their rivals without starting quarterback Jalen Hurts.
Hurts is out with a sprained shoulder, meaning the Eagles will be hoping for backup Gardner Minshew to reprise 'Minshew Mania' and lead them to triumph.
The absence of Hurts may remove the downfield passing element from the Eagles' offense and will also have a negative impact on the Philadelphia ground game.
Hurts rushed for three touchdowns in last week's win over the Chicago Bears, taking his tally to 26 for his career. The only Eagles quarterbacks with more are Randall Cunningham (32) and Donovan McNabb (28).
Still, the Eagles do have one of the most productive running backs in the NFL this season in the form of Miles Sanders, who has averaged 5.16 yards per carry in racking up 1,110 rushing yards. That number ranks fifth in the NFL, as do his 11 rushing touchdowns.
Sanders may be the focal point for the offense for Philadelphia in Week 16, with the onus potentially on him to increase the Eagles' tally of eight rushing touchdowns of 10 yards or more, one which trails only the Cowboys and the Seattle Seahawks (both nine).
Yet there is the distinct possibility that both teams find it tough sledding on the ground. The Eagles and the Cowboys have each allowed only three rushing touchdowns of at least 10 yards.
With Dallas able to complement a running game led by the exciting tandem of Ezekiel Elliott and Tony Pollard with a passing attack overseen by Dak Prescott, the Cowboys have a greater number of avenues towards offensive success. Prescott is fourth among quarterbacks with at least 200 attempts in well-thrown rate. He has delivered an accurate, well-thrown ball on 85.4 per cent of his passes.
The change from Hurts to Minshew makes the Eagles' offense more of an unknown, but if they can survive their starting quarterback's absence and prevail, it will underline their status as the top team in the NFC, if not the NFL.