Premier League leaders Arsenal went into the international break with an eight-point advantage, and the Gunners will be hoping for a favour from Liverpool on Saturday.

Before Arsenal host strugglers Leeds United, Liverpool travel to the Etihad Stadium to face second-placed Manchester City.

Pep Guardiola's side have a game in hand on Arsenal, but surely they must beat the Reds to give themselves a realistic chance of retaining the title.

Elsewhere, there are more huge fixtures at the bottom of the table, including West Ham v Southampton, while Newcastle United and Manchester United play in a repeat of February's EFL Cup final.

Manchester City v Liverpool

Liverpool, who won the reverse league fixture 1-0, are looking to complete the league double over City for what would be just a second time in the last 17 seasons, previously doing so in Jurgen Klopp's debut campaign in 2015-16.

Mohamed Salah has scored in all three of Liverpool's games against Man City this season, in the Premier League, Community Shield and EFL Cup. The last Liverpool player to score in four different games against an opponent in a single campaign was Ian Rush, netting in five meetings with Everton in 1986-87.

Erling Haaland has scored 42 goals in all competitions for City this season, including six hat-tricks (all at the Etihad). Only two players have scored more in a single campaign for a Premier League club (since 1992-93) – Ruud van Nistelrooy in 2002-03 and Salah in 2017-18 (both 44).

Best bet – City to avoid defeat:  City have lost just one of their last 13 Premier League home games against Liverpool (W7 D5), going down 4-1 in November 2015 under Manuel Pellegrini. Guardiola's team have won their last three top-flight games, but have yet to win four in a row this season. 

Long shot – Liverpool to win:  Liverpool have won more Premier League games against reigning champions than any other side (23). They are aiming to achieve their first such double since 2013-14, beating Manchester United 1-0 at home and 3-0 away. However, they have taken just 12 points from their 13 Premier League away games this season (W3 D3 L7), compared to 30 at home.

Opta prediction: Despite the fierce rivalry over recent years, City are the big favourites for this game, with Opta's supercomputer ranking their chances of victory at 50.9 per cent. The draw is at 26.4 per cent, with Liverpool handed a 22.7 per cent chance of success.

Arsenal v Leeds United

Leeds have won just two of their 23 Premier League games against the league leaders (D9 L12), though both victories came away from home (v Middlesbrough in August 2000 and Man City in April 2021). They have lost all four such games against Arsenal by an aggregate score of 14-2.

Arsenal have won their last six Premier League games, their joint-longest such run under Mikel Arteta. They last won seven in a row between August and October 2018 under Unai Emery.

Arsenal’s top scorer in the Premier League this season is Gabriel Martinelli with 13 goals. The last player to score more while aged 21 or under in a single campaign in the division was Dele Alli in 2016-17 (18).

Best bet – Bukayo Saka to score or assist: Only Erling Haaland (33) and Harry Kane (23) have been involved in more Premier League goals than Saka this season (22), with the winger the only player so far to reach double figures for both goals (12) and assists (10).

Long shot – Leeds to keep a clean sheet: Since a 0-0 draw in their first Premier League away game against Arsenal in February 1993, Leeds have not drawn or kept a clean sheet in any of their subsequent 13 league visits to the Gunners (W3 L10), shipping 31 goals in total.

Opta prediction: Opta do not give Leeds much chance at Emirates Stadium (15.5 per cent). Arsenal are huge favourites, with a 61.6 per cent win probability, while the draw is ranked at 22.9 per cent.

West Ham v Southampton

Coming into this weekend's games, Southampton have picked up the highest share of their Premier League points this season away from home (57 per cent - 13/23). Meanwhile, only Nottingham Forest (77 per cent) have a higher share of points won at home in 2022-23 than West Ham (75 per cent - 18/24).

Southampton have picked up as many points in their six Premier League games under Ruben Selles (8 – W2 D2 L2) as they had in their 17 league matches beforehand (W2 D2 L13).

Sides starting the day bottom of the Premier League have won 11 league matches this season, four more than the whole of last term (seven), and the most in a single campaign in the competition since 2017-18 (12). Southampton have been responsible for three of those victories by bottom-placed sides in 2022-23, a joint-high (also Leicester).

Best bet – James Ward-Prowse to create two chances:  Coming into this weekend's games, only Kieran Trippier (49) has created more chances from set plays than Ward-Prowse (35) in the Premier League this season, while the Southampton captain is the only player to create 25+ chances from both open play (27) and set pieces (35) in the division this term.

Long shot – A goalless draw: No other sides have kept fewer clean sheets in the Premier League this season than Southampton (four) and West Ham (five)

Opta prediction: Despite both of these teams struggling, it is West Ham who Opta give 51.4 per cent chance of claiming all the points. Southampton have been responsible for three of the seven victories by the bottom-placed side this season, but the likelihood of them succeeding this time stands at 21.7 per cent. 

Newcastle United v Manchester United

Following their goalless draw at Old Trafford in the reverse fixture, Newcastle are looking to keep a clean sheet in consecutive Premier League games against United for the first time since May 1997.

No player has scored more winning goals in the Premier League this season than Marcus Rashford, with nine of his 14 strikes being the winner. Only two United players have ever scored more winning goals in a single campaign in the competition – Cristiano Ronaldo (12 in 2007-08) and Wayne Rooney (10 in 2009-10).

Coming into this weekend's fixtures, only Bournemouth (38), Nottingham Forest (32) and Leicester (30) have conceded more away goals in the Premier League this season than United (27). Indeed, only in four different Premier League campaigns have the Red Devils conceded more on the road – 1999-00 (29), 2001-02 (28), 2018-19 (29) and 2021-22 (35).

Best bet – United to win: United have won more Premier League away games against Newcastle than any other side (14). However, they have lost two of their last five such visits (W2 D1), having lost just one of their previous 13 at St James' Park. Newcastle are winless in six Premier League games against Man Utd (D2 L4), though the last two have both been drawn.

Long shot – Rashford and Alexander Isak to score: Rashford has been involved in seven goals in his eight Premier League starts against Newcastle (four goals, three assists) – only against Arsenal and Leicester City (nine each) has he been involved in more. Isak, meanwhile, has scored six goals in 10 Premier League appearances for Newcastle this season, including three in his last two. 

Opta prediction: This could prove a big game in the top-four race, with Newcastle only three points behind third-placed United. The visitors are made very slight favourites (36.8 per cent to 34.2 per cent). The draw is given a 29 per cent chance.

Everton manager Sean Dyche is focused on the club's fight to avoid relegation after the Toffees were referred to an independent commission over an alleged breach of the Premier League's financial rules.

Last week, the Premier League alleged Everton had broken the competition's profitability and sustainability rules during the 2021-22 season, which they finished in 16th place.

Everton ended last season four points clear of the relegation zone, but the Merseyside club have found themselves embroiled in another battle to stay in the top flight this term.

With reports suggesting Everton could face a point deduction, a club statement said the Toffees were "prepared to robustly defend" their position.

Asked about the alleged breach on Thursday, Dyche said: "There is no situation at the moment. The club's statement covers everything. I'm happy to go along with that. 

"I'm more focused on what's going on on the pitch, obviously. The club have assured me the statement is correct and the rest of it will come down to the powers that be to do what they have to do.

"At the minute, we are really focusing on what is going on now. Of course there are background views on the future but I'm working with the squad now, working to get more points and to make sure we get what we all want, which is to be in the Premier League."

Everton sit two points above the bottom three ahead of Monday's meeting with Tottenham at Goodison Park, having salvaged a 2-2 draw at Chelsea prior to the international break.

Dyche also confirmed striker Dominic Calvert-Lewin is "back out on the grass" and progressing well from injury, but he not yet ready to participate in full sessions.

Hugo Lloris could feature for the first time in almost two months when Tottenham visit Everton on Monday, having recovered from a knee injury to return to full training.

Spurs captain Lloris sustained the injury during a 1-0 win over Premier League champions Manchester City on February 5, causing him to miss the team's last nine matches.

Fraser Forster has deputised throughout that spell, which has seen Spurs exit the Champions League and the FA Cup, while they parted company with boss Antonio Conte after a 3-3 draw at Southampton prior to the international break.

While Lloris' return provides a boost for acting head coach Cristian Stellini, full-back Emerson Royal has joined Yves Bissouma, Rodrigo Bentancur, Ben Davies and Richarlison on the injury list.

"Hugo is training," Stellini told Spurs' website on Thursday. "It's a week where he has trained with the team. 

"We had a training match where we could let Hugo feel the pitch again. We will recover Hugo, but we have problems with other players.

"This is football. We have injured players, but we also believe in all the players. 

"We have a big squad; we also have young players ready, and we trust in them, like we trusted Pape Sarr and Oliver Skipp when they started to play. Young players are involved in our squad and if we need them, they are ready to play."

Everton manager Sean Dyche is focused on the club's fight to avoid relegation after the Toffees were referred to an independent commission over an alleged breach of the Premier League's financial rules.

Last week, the Premier League alleged Everton had broken the competition's profitability and sustainability rules during the 2021-22 season, which they finished in 16th place.

Everton ended last season four points clear of the relegation zone, but the Merseyside club have found themselves embroiled in another battle to stay in the top flight this term.

With reports suggesting Everton could face a point deduction, a club statement said the Toffees were "prepared to robustly defend" their position.

Asked about the alleged breach on Thursday, Dyche said: "There is no situation at the moment. The club's statement covers everything. I'm happy to go along with that. 

"I'm more focused on what's going on on the pitch, obviously. The club have assured me the statement is correct and the rest of it will come down to the powers that be to do what they have to do.

"At the minute, we are really focusing on what is going on now. Of course there are background views on the future but I'm working with the squad now, working to get more points and to make sure we get what we all want, which is to be in the Premier League."

Everton sit two points above the bottom three ahead of Monday's meeting with Tottenham at Goodison Park, having salvaged a 2-2 draw at Chelsea prior to the international break.

Dyche also confirmed striker Dominic Calvert-Lewin is "back out on the grass" and progressing well from injury, but he not yet ready to participate in full sessions.

The Premier League has referred Everton to an independent commission over an alleged breach of profitability and sustainability rules.

It was announced by the Premier League on Friday that the Toffees are alleged to have broken the regulations during the 2021-22 season.

Everton finished only four points above the relegation zone last season as Norwich City, Watford and Burnley dropped into the Championship.

The Merseyside club are embroiled in another fight to stay in the top flight, sitting in 15th place and only two points better off than third-bottom West Ham – who have two games in hand on Sean Dyche's side.

Everton face an anxious wait to discover if they will be hit with a points deduction.

A Premier League statement said: "In accordance with Premier League Rule W.82.1, the Premier League confirms that it has today referred an alleged breach of the League's profitability and sustainability rules by Everton Football Club to a commission under Premier League Rule W.3.4. The assessment period for which it is alleged that the club is in breach is the period ending season 2021/22.

"Commissions are independent of the Premier League and member clubs. The members of the commission will be appointed by the independent Chair of the Premier League Judicial Panel, in accordance with Premier League Rules W.19, W.20 and W.26.

"The proceedings before the commission will, in accordance with Premier League rule W.82, be confidential and heard in private.

"Under Premier League rule W.82.2, the commission’s final award will be published on the Premier League's website. The League will be making no further comment until that time."

Ellis Simms hailed "a massive point" for Everton after the striker's first Premier League goal earned a 2-2 draw at Chelsea, his late heroics earning praise from Sean Dyche.

The substitute struck in the 89th minute at Stamford Bridge, brushing off Chelsea's Kalidou Koulibaly before beating Kepa Arrizabalaga at his near post.

It was a moment neither the defender nor goalkeeper would want to look at again, but it will live long in the memory for Simms, an Oldham-born youngster who has shown his goalscoring potential in loans with Hearts, Blackpool and Sunderland.

Now he has a goal at the top level of English football, and the point pushes Everton two points clear of the relegation zone.

Everton have now had 13 different goalscorers in the Premier League this season, with only Arsenal, Chelsea and Leeds United (14 each) having more.

They have not won in the league at Chelsea since 1994, a barren run of 28 games (D13 L15), but Everton were the side with the most to celebrate on this occasion.

Simms said the equaliser was "100 per cent" the biggest moment of his career.

"It's a great occasion to do it," he told Sky Sports. "I'm delighted for the team as well – a massive point against tough opposition, so we're delighted, we're made up.

"I've been working hard at Everton to come up with this, and it's a dream to come true to get my first Premier League goal.

"It's about patience. I've had to wait for my chance. Obviously we've got top players, so I'm not just going to walk straight into the team I just have to work hard in training and when I get the opportunity I have to take it, grab it with both hands."

Simms said there was "massive belief" in the ranks, and manager Dyche spoke glowingly of the 22-year-old, who has started just one league game so far for the Toffees this term, surprisingly being given the nod for February's derby with Liverpool.

"He's a young lad earning his spurs," Dyche said. "We threw him in against Liverpool, it was probably a bit too much on that night, but he's still around the group, he's working hard, he's realising the hard yards are important in the sides I work with, and he's maturing into it.

"He has scored goals, albeit in the Championship, and he's delivered with his pace and his power to break free and then gets a nice finish under the body of the keeper."

Chelsea head coach Graham Potter said his team's general play had been "a step forward", even after recent wins against Leeds United, Borussia Dortmund and Leicester City.

Their defending left plenty to be desired, though, so Joao Felix's low strike and Kai Havertz's penalty were only good enough for a point, leaving Chelsea 10th in the table, with Abdoulaye Doucoure cancelling out the first of the hosts' goals before Simms had his late say.

"I thought the performance overall was positive," Potter said. "We did a lot of things really well, scored a couple of goals, but ultimately didn't defend well enough in a couple of actions which has cost us, and we're disappointed to drop points."

Asked about the late concession, Potter said: "It looked too easy throughout the team, so I was disappointed from my perspective with the second goal, and the first as well.

"It was a positive performance from us overall, but it's hard to say that when you've only got one point."

Leeds United, Everton, Southampton and Leicester City all earned big results on Saturday in their efforts to beat the drop.

The Premier League's struggling sides were the big winners from the five matches to take place.

Leeds beat fellow relegation candidates Wolves 4-2, while Everton pegged back Chelsea twice at Stamford Bridge and Southampton came from 3-1 down to draw 3-3 with Tottenham.

Leicester, meanwhile, snatched a draw at Brentford, though 19th-placed Bournemouth lost 3-0 at Aston Villa.

Wolves 2-4 Leeds United: Six-goal thriller and two reds at Molineux

Leeds came out on top in an enthralling encounter at Molineux, with Javi Gracia's side claiming what could be a vital three points in their bid to survive this season.

Jack Harrison put them ahead early on, and he has now been directly involved in four goals (two goals, two assists) in his four Premier League games under Gracia, just one fewer than in his previous 21 matches under Jesse Marsch and Michael Skubala this season (five).

Luke Ayling netted his first league goal since doing so against Wolves exactly a year ago (March 18, 2022) to make it 2-0, with Rasmus Kristensen putting Leeds three ahead.

Their hopes of a comfortable win were dashed when Illan Meslier, on the day he became the youngest goalkeeper in Premier League history to reach 100 appearances, made a mistake that Jonny pounced on, volleying in from 41 yards. That is the furthest distance a player has scored from in the top flight since Wayne Rooney's 58-yard strike for Everton against West Ham in November 2017.

A deflected Matheus Cunha strike gave Wolves hope, but Jonny became the first Wolves player to both score and be sent off in any league game since September 2008. 

Julen Lopetegui was fuming that Wolves were not awarded a first-half penalty and that a foul was not given in the build-up to Rodrigo's late effort for Leeds, with Matheus Nunes then sent off even though he was on the substitutes' bench.

"I'm not waiting for [further apologies]. I just want them [the officials] to do their job," Lopetegui said.

Southampton 3-3 Tottenham: Conte left seething after Ward-Prowse seals comeback

Southampton came from two goals down to avoid defeat for a second time in the Premier League this season, with only Manchester City (P3 W2 D1) avoiding defeat having fallen two goals behind on more occasions this term.

Tottenham, who took the lead through Pedro Porro but saw it cancelled out by Che Adams, restored their advantage through Harry Kane – he has now scored nine headers in the league this season, equalling Duncan Ferguson's single-season record in the competition from 1997-98.

Ivan Perisic took Spurs' tally of Premier League scorers to 162, with only West Ham (164) having more different scorers in the competition's history, yet Theo Walcott pulled one back for Saints. The former Arsenal winger has more top-flight goal involvements (12) and goals (seven) against Tottenham than he does against any other opponent.

Yet Spurs conceded a 14th goal since the season restarted when Pape Sarr was deemed to have fouled Ainsley Maitland-Niles, and James Ward-Prowse converted the penalty. He has been involved in more Premier League goals against Tottenham than he has any other opponent (nine – five goals, four assists).

Brentford 1-1 Leicester City: Barnes holds the Bees

Brentford remain without a win against Leicester in the Premier League (P4 D2 L2). The Bees have not beaten the Foxes in the league since March 1953 (P8 D3 L5 since).

Leicester ended a run of four consecutive defeats in the Premier League but this was just the eighth point they have picked up in 2023 (P10 W2 D2 L6). Only Crystal Palace (five) have picked up fewer points since the turn of the year, while only Everton and Bournemouth (20 and 18 respectively) have conceded more goals in the competition this calendar year than Leicester's 17.

Only Ivan Toney (eight) has scored more home goals for Brentford in the Premier League this season than Mathias Jensen (five), whose goal was the Bees' 19th from a set-piece this term – more than any other side in the division.

Leicester scored from their only shot on target of the game. Harvey Barnes' goal was his ninth of the season – his joint-most in a single Premier League campaign (also nine in 2020-21).

Chelsea 2-2 Everton: Simms snatches huge point

Substitute Ellis Simms scored his first goal for Everton as Sean Dyche's team drew 2-2 at Stamford Bridge, twice coming from behind.

Chelsea are unbeaten in their last 28 Premier League home games against Everton (W15 D13), but the Toffees can take plenty of confidence from this result.

Joao Felix put Chelsea ahead with his first home goal for the Blues, but Abdoulaye Doucoure equalised from a corner; four of Everton's seven goals under Dyche have come from set-pieces.

Kai Havertz converted a spot-kick to restore Chelsea's lead. He has scored in three consecutive games for the Blues for the second time, previously doing so in March 2022.

However, Simms came on from the bench to earn a point for Everton. The Toffees have now had 13 different goalscorers in the competition this season, with only Arsenal, Chelsea and Leeds (14 each) having more.

Ellis Simms stunned Chelsea with a late leveller as the striker's first Premier League goal gave Everton a dramatic 2-2 draw at Stamford Bridge.

Joao Felix had opened the scoring with his second goal in the competition since arriving at Stamford Bridge in January, with Chelsea looking good to brush off opponents who had offered very little going forward.

Everton surprisingly got level when Abdoulaye Doucoure nodded in from a corner, but a penalty from Kai Havertz restored Chelsea's lead.

A home win looked all but assured, yet Everton grabbed an 89th-minute equaliser when substitute Simms strode through and beat Kepa Arrizabalaga, halting Chelsea's three-game winning run.

Graham Potter has noted the change in atmosphere around Chelsea following their positive recent run, which his side will hope to continue against Everton.

Potter was under huge pressure at Stamford Bridge after a dismal stretch that saw only two wins in 15 matches in all competitions.

But Chelsea have since won three in a row, with Premier League victories over Leeds United and Leicester City sandwiching a vital Champions League win over Borussia Dortmund.

Emboldened by those results, Potter met with fans at an event this week and told them he would "try to win the f***ing Champions League".

That enthusiasm could have been dampened by Friday's draw, in which Chelsea were paired with Real Madrid on the same side of the bracket as Manchester City and Bayern Munich, but Potter remained upbeat ahead of Saturday's meeting with Everton.

"It was a nice event in front of 1,000 or so supporters. The atmosphere was good," Potter said after a clip of his rallying cry appeared on social media.

"It was a good evening. Results give everyone belief and happiness, and we're here to win."

Everton have also improved of late under Sean Dyche, winning three of their last seven to give themselves a fighting chance in the relegation battle.

All of those victories have come at home, but Dyche hopes his side have the mentality to take that form on the road – starting at Chelsea.

"It's more the consistency of the mentality, home games going into away games," he said. "It's the mentality and saying, 'look we're going to take it on'.

"There's certain tactical things that may change, but generally speaking, the mentality is massive.

"There's some tactical tweaks sometimes, certain grounds you might not have the ball as much, but you've got to find ways of winning, and we're trying to build a mentality where we can win games under different circumstances."

PLAYERS TO WATCH

Chelsea – Mykhaylo Mudryk

Chelsea played some thrilling football in the win at Leicester and, to the relief of some supporters, there was a role in that team for Mykhaylo Mudryk.

The winger had previously lost his place in the side and did not even appear from the bench against Leeds and Dortmund, but his wait for a first goal involvement was ended with an assist for Mateo Kovacic. Mudryk will hope a first goal is not far away.

Everton – Demarai Gray

With Everton still without Dominic Calvert-Lewin, Gray was handed a striking role last time out against Brentford.

Although he did not score, no Everton player was involved in more shots (three shots, two key passes). Dyche will likely rely on the winger-turned-forward's nuisance factor again at the Bridge.

MATCH PREDICTION – CHELSEA WIN

Although Everton have beaten Chelsea in each of the previous four seasons, all of those wins came at Goodison Park. They have a miserable record in west London.

Indeed, Chelsea are unbeaten in their last 27 Premier League home games against Everton. Against no side have they ever had a longer unbeaten run at Stamford Bridge in their top-flight history.

And the Blues have started to find form at both ends of the pitch. They have scored five goals across their past two games, as many as they had in their previous 12 in all competitions, and are looking to keep three consecutive home clean sheets in all competitions for the first time since September 2021.

OPTA WIN PROBABILITY

Chelsea – 54.1 per cent

Everton – 19.3 per cent

Draw – 26.6 per cent

Graham Potter acknowledged Chelsea's turnaround in form has involved an element of luck, though he also praised the "fight" of his players as he bids to continue the team's recent revival.

The Blues have won their last three games across all competitions, having previously struggled to string together a run of results since the mid-season restart.

Progress to the Champions League quarter-finals – where they have been rewarded with a tie against holders Real Madrid – has helped to ease the immediate pressure on Potter.

But ahead of Chelsea's final game before the March international break, a clash against Everton at home in the Premier League, Potter acknowledged his side had still needed the wind to blow their way in recent weeks.

"You need luck," he said after the wins over Leeds United, Borussia Dortmund and Leicester City.

"As much as you can be good, it is important to be lucky.

"But you can't wait for that to come around and sometimes you have to fight through the storm.

"We've come out of it with three wins, but we need to carry that form on. Now there are three points up for grabs against a tough team."

Pressed on drawing Real Madrid in the Champions League, a few days after he outlined his desire to lead the Blues to success in the competition, Potter insisted his focus was the Everton fixture on Saturday.

But on the subject of ex-Toffees boss Carlo Ancelotti, who is chasing back-to-back triumphs with the Spanish side in Europe, he was unequivocal in his praise.

"I've played against him when he was at Everton," he added. "He is a gentleman and there's nothing I can say in terms of the respect I have for what he's achieved in his career.

"I think the length of time he's had between Champions League wins – twenty years – is incredible.

"[But] where we are now is to focus on Everton. They play to their strengths and that is what we must focus on."

Arsenal crashed out of the Europa League with a penalty shoot-out defeat to Sporting CP on Thursday, and Mikel Arteta will be looking for an instant response in the Premier League.

The title is now their sole focus, and with Manchester City in FA Cup action this weekend, the Gunners can move eight points clear at the top should they beat Crystal Palace, who on Friday sacked Arsenal great Patrick Vieira after an 11-game winless run.

Palace are 12th but only three points above the relegation zone, and that picture could change by the time they play on Sunday.

After Nottingham Forest welcome Newcastle United on Friday, Bournemouth visit Aston Villa, Leicester City have a tough trip to Brentford, Southampton host Tottenham, and Wolves and Leeds United face off in another big match at the bottom of the table. Everton, who are also in the relegation scrap, play Chelsea at Stamford Bridge.

Here, with the help of Opta data, Stats Perform has provided some key insights and predictions.

Southampton v Tottenham 

Between December 2019 and January 2021, Southampton won five of six Premier League games against sides starting the day in the top four of the table (L1). However, since then they are winless in 15 such games (D6 L9), conceding 43 goals and scoring just nine in return.

Southampton have scored at least once in each of their last 14 Premier League games against Spurs, since a 2-0 home loss in December 2015, but they have kept just one clean sheet in their last 21 against them, when they won 1-0 in January 2020.

In all competitions, Tottenham have lost each of their last four away games, the last three of which without scoring. This is Spurs' longest run of away defeats in succession since May 2019 (five in a row), while not since January 1983 have they lost four straight away matches without scoring (a run of five).

Best bet – Harry Kane to score or assist: Harry Kane has been directly involved in 17 goals in 15 Premier League appearances against Southampton (11 goals, six assists), having only had a hand in more goals against Leicester (22). The England captain has scored nine away goals in the competition this season – no other player in Premier League history has netted 10 times on the road in more than four separate campaigns, whereas Kane is on the verge of doing so for the seventh time.

Long shot – Richarlison to score: Richarlison was desperately unlucky not to break his duck for Spurs in the win over Forest last week, with a fierce finish ruled out for offside. The Brazil forward has netted five times in his last seven league appearances against Saints, making them his favourite team to play against when it comes to goals, but he is yet to score in the Premier League this season.

Opta prediction: Spurs are made favourites for this one by Opta's supercomputer, with Antonio Conte's team given a 54 per cent chance of victory. There is roughly a one in four chance of a draw (25.7 per cent), while Southampton, who prop up the table but could move as high as 15th with a win, are given a 20.3 per cent chance of claiming the spoils.

Wolves v Leeds United

Having been unbeaten in six league games against Leeds between 2017 and 2021 (W5 D1), Wolves have lost their last two against the Whites. Indeed, Leeds are looking to complete their first league double over Wolves since 2015-16 and their first in the top flight since 1973-74.

Leeds, who will be without key midfielder Tyler Adams due to a hamstring issue, have earned four points from their three Premier League games under Javi Gracia (W1 D1 L1), as many as they had in their 10 games before his arrival (W0 D4 L6). However, they are winless in their last seven away matches (D2 L5). 

Wolves boss Julen Lopetegui has won both of his previous meetings with Gracia in all competitions. These games came in the 2020-21 campaign, with Lopetegui's Sevilla beating Gracia's Valencia 1-0 in LaLiga and 3-0 in the Copa Del Rey.

Best bet – Wolves to avoid defeat: No side have fewer away wins (one) or away points (six) in the Premier League this season than Leeds, who have lost nine of their 13 away league games this term. Wolves, meanwhile, have won three of their last four home league games (L1), more than they had in their previous 12 (W2 D3 L7). 

Long shot – Wolves to score over two goals: Wolves have a shot conversion rate of 6.8 per cent in the Premier League this season, their lowest in any of their nine campaigns in the competition. Only once have they scored more than twice in a top-flight game this term, when they beat Liverpool 3-0 in February.

Opta prediction: Expect this one to be close, based on the prediction model, which makes Wolves the slight favourites (39.3 per cent), although Leeds are at 31.3 per cent. A draw is certainly feasible and is given a 29.4 per cent chance.

Chelsea v Everton

Chelsea are unbeaten in their last 27 Premier League home games against Everton (W15 D12) since a 1-0 loss in November 1994. Against no side have they ever had a longer unbeaten run at Stamford Bridge in their top-flight history. Everton managed a 1-1 draw with a makeshift side in the corresponding fixture last season, but a win still evades them.

Before this season, Everton had beaten Chelsea in each of the last four Premier League campaigns, although all of their victories were at home. They have not beaten the Blues in five straight league seasons since the 1930s.

Everton have won three of their seven Premier League games under Sean Dyche so far (D1 L3), as many as they had in their 20 matches under Frank Lampard this season (D6 L11), but again all of those wins have come at home.

Best bet – Chelsea to win: Everton are winless in their last 11 Premier League away games against London sides (D3 L8), failing to score in each of the last four, and Chelsea have only failed to beat the Toffees at home twice since the start of the 2016-17 season.

Long shot – Everton to win 1-0: If the visitors are to claim a victory, expect it to be a cagey one. In fact, 40 per cent (30) of Dyche's 75 Premier League wins have been by a 1-0 scoreline, including his three as Everton boss. Of the 52 managers with at least 50 wins in the competition, only Tony Pulis (42 per cent – 41 of 98) has won a higher share by a 1-0 scoreline.

Opta prediction: Given Everton's torrid form on the road – they have won fewer Premier League away games (three) and earned fewer points on the road (18) than any of the 17 ever-present sides since the start of last season – and dismal record at Stamford Bridge, Chelsea are the overwhelming favourites at 54.1 per cent on Opta's model. Everton are handed a slim 19.3 per cent chance of success, while the draw is rated at 26.6 per cent.

Arsenal v Crystal Palace 

Palace elected to part ways with Arsenal legend Vieira and could well be further embroiled in the relegation battle by the end of Sunday's game. After all, the Gunners have won their last five Premier League matches, netting at least three goals in four of those, including each of the last three. 

Arsenal have won eight of their nine London derbies in the Premier League this season (D1); in English Football League history, no side have ever won nine all-London match-ups in a single season. Palace, on the other hand, have won just one of their eight derbies this term. The Eagles have, however, avoided defeat in their last four Premier League away games against Arsenal, with each of the last three ending level (W1).

Since his Premier League debut for Arsenal in January, no player has been involved in more goals for the Gunners than Leandro Trossard (six – one goal, five assists). He has five assists in his last four Premier League games, as many as in his previous 64 appearances.

Best bet – Gabriel Martinelli to have 2+ shots on target: After missing the crucial penalty in Arsenal's shoot-out loss to Sporting in Europe, Martinelli will be determined to put things right. He is Arsenal's highest goalscorer in the Premier League this season with 12 goals, including five in his last five appearances. 

Long shot – Palace to keep a clean sheet: Palace have kept just one clean sheet in 22 away league games against Arsenal (49 goals conceded), a goalless draw in January 2021, while the Gunners have scored in all but one of their league games at Emirates Stadium this season.

Opta prediction: Arsenal are the favourites, although given the respective form of these sides, a 54.6 per cent win prediction perhaps feels a bit low – a reflection of Palace's recent unbeaten run at Emirates Stadium. Opta gives the draw a 26.5 per cent chance, while the supercomputer has a Palace win ranked at 18.9 per cent.

Kepa Arrizabalaga looked to be yesterday's man at Chelsea, but such has been his recent form the goalkeeper might have a long-term role to play for the Blues.

He might also be a quick fix this weekend if your fantasy league goalkeeper is having a rough time of it.

In north London, title-chasing Arsenal have a pillar of strength in their backline, and a goal threat too, as Gabriel Magalhaes makes his presence felt at each end of the pitch.

Chelsea face Everton this weekend, while Arsenal tackle Crystal Palace, and away from the capital there is a chance for Ollie Watkins to show his prowess as Aston Villa take on Bournemouth.

Tottenham, still in the hunt for a Champions League place, travel to Southampton with Son Heung-min facing perhaps his favourite opposition.

Using Opta data, Stats Perform has assessed why these four players could help your fantasy league team bring in useful points this weekend.
 

Kepa Arrizabalaga (Chelsea v Everton)

The turnaround in Kepa's Chelsea career has been astonishing. From looking destined to be a permanent understudy, he has responded to Edouard Mendy's injury absence by making a huge impression and staking a strong claim to keep his place for the long term. Since the World Cup, only Alisson and David de Gea, each with six shutouts, have kept more clean sheets than Arrizabalaga (5).

Spaniard Kepa's 79.55 per cent save rate in this period has been bettered only by Brentford's David Raya (84.62), and this weekend he faces an Everton side who have a joint-worst goals-per-game record this season. The Toffees have 20 goals in 27 Premier League games, or just 0.74 goals per game, the same record as Southampton and Wolves.

Gabriel Magalhaes (Arsenal v Crystal Palace)

Gabriel got Arsenal's opener in the 3-0 win at Fulham last week, and the central defender can be a set-piece threat in another London derby on Sunday.

The Brazilian's goal at Craven Cottage was his 10th in the Premier League, more than any other defender has managed since his debut in 2020-21. This season, no defender has more Premier League goals (3) or clean sheets (12) than the Brazilian, so can you really afford to be without him?

Ollie Watkins (Aston Villa v Bournemouth)

Villa striker Watkins netted his 100th English league goal last time out (excluding play-offs) and is one away from reaching 10 Premier League goals for a third successive season.

Bournemouth will be on their guard, no doubt, a week on from shutting out Liverpool. Watkins has scored six goals in his last seven Premier League games, with only Marcus Rashford (8), Erling Haaland and Harry Kane (both 7) netting more in 2023.

Watkins has missed out on selection for the latest England squad, so he may also feel he has a point to prove this weekend.

Son Heung-min (Southampton v Tottenham)

Son hit four for Tottenham at St Mary's in September 2020, when the pandemic made it a behind-closed-doors game.

The South Korean forward has more goals (10) and more goal involvements (14) against Southampton than he has against any other side in the competition, including eight goal involvements in his last six games against them (6 goals, 2 assists).

He scored in the win over Nottingham Forest last weekend, and will fancy it against struggling Saints.

Paris Saint-Germain's Champions League last-16 exit has prompted speculation about a squad overhaul.

Neymar's future in the French capital is in doubt, while pressure has ramped up on head coach Christophe Galtier.

PSG will be an interesting watch during the next transfer window as they show their hand on their future direction.

TOP STORY – PSG PLOT MOVES FOR SILVA AND DEMBELE

Paris Saint-Germain are plotting off-season moves to sign Manchester City midfielder Bernardo Silva and Barcelona winger Ousmane Dembele , according to Diario Sport.

The Parisiens are monitoring Dembele's status at the Blaugrana with only one year left on his contract, with a €50million release clause.

Barcelona have been linked with Silva but may struggle to facilitate that deal given €65m asking price, with PSG better placed to table that figure.

The report claims PSG's move for Dembele hinges on Neymar and whether he stays in Paris.

  
ROUND-UP

– AS reports Real Madrid are still angling to sign PSG's Kylian Mbappe after a long courtship. The report claims Los Blancos want to sign him as a free agent when his contract expires in 2024 and have prioritised him over Man City's Erling Haaland .

– Tottenham are ready to launch a move to sign Everton goalkeeper Jordan Pickford on a cut-price deal, according to The Sun. The report claims Pickford has a clause in his new Everton deal, signed last month, if they are relegated although the Toffees are understood to want around £35m.

– PSG are planning a bid for Villarreal defender Pau Torres in the next transfer window, reports The Mirror. Manchester United opted against signing him last year.

– Barcelona 's top priority in the off-season is to sign Athletic Bilbao defender Inigo Martinez , according to Sport.

– Calciomercato claims Milan have cooled their interest in Liverpool midfielder Naby Keita as his wage demands are beyond what they can offer.

– Bayern Munich continue to monitor the status of Juventus forward Dusan Vlahovic , reports Calciomercato.

Mikel Arteta challenged his Arsenal players to be relentless in their bid for the Premier League title after they moved five points clear of Manchester City, declaring: "We're not going to stop".

Gabriel Martinelli's brace, coupled with goals from Bukayo Saka and Martin Odegaard, helped Arsenal crush struggling Everton 4-0 in their game in hand over rivals City on Wednesday.

While Arsenal started slowly against Sean Dyche's side, they eventually turned on the style to win their third league game in a row – and claim their 100th league victory against Everton.

The Gunners' commanding win puts daylight between them and second-placed City – who briefly overhauled them at the summit following a 3-1 victory at the Emirates Stadium last month.

Asked whether Arsenal's thrashing of Everton made them title favourites, Arteta said: "You know my answer there! 

"What I like is that everybody has the enthusiasm to do it, and we're not going to stop that – we have to promote that.

"But the way to promote that is by looking at this game and understanding that we have to do a lot of things better, especially in the first half. 

"We can play better and make sure we prepare really well against Bournemouth, because that's going to be a tough game."

Asked how Arsenal could find the mental strength required to beat City to the title, Arteta said: "It is something that we have to train and discuss and build. 

"It is not easy, but a lot of time it happens through experiences and most of the time they are experiences that you don't want to go through, but the calendar and fixtures are going to give that. 

"Sometimes you are where we are now, sometimes it is three points [difference], two points, minus two – it is going to happen and we have to live with that."

Arsenal take on relegation-threatened Bournemouth in their next game on Saturday, before switching their attentions to a Europa League last-16 tie against Sporting CP.

Mikel Arteta hailed Arsenal's ability to solve problems after they overcame a hesitant start to thrash Everton 4-0 at the Emirates Stadium, moving five points clear at the Premier League summit.

Arsenal were kept quiet for 40 minutes on Wednesday by Sean Dyche's Toffees – who inflicted a surprise 1-0 defeat on the Gunners less than a month ago, but the floodgates opened with a quickfire double before the break.

Bukayo Saka hammered home the opener before Gabriel Martinelli got the second, with both men reaching double figures for Premier League goals this term to put Arsenal in control.

Skipper Martin Odegaard then added a third before Martinelli clinched his brace late on, dealing Everton their heaviest league defeat since they were thrashed 5-1 on the same ground last season.

The comprehensive victory saw Arsenal put daylight between themselves and second-placed Manchester City, and Arteta was delighted by the way his team grew into the game.

"I'm happy, we won in a convincing way after 20 or 25 minutes in the first half where we had some difficulties attacking that block, with the really good organisation they have," Arteta told Sky Sports.

"We were getting a little bit frustrated and allowed them to run in transition in a few moments.

"But afterwards we got control of the game, we scored two goals in perfect time, I would say, just before the break.

"Then the second half was really convincing, the way we attacked them, the composure in the box to score the goals that we wanted… I'm really happy.

"Everton posed some real questions – especially with how we could attack against that block, as they are really good at that.

"But we also had to not give them a licence to grow into the game, to play close to our goal and produce set-pieces, and I think we did that really well."

Arsenal's victory made them the first team in English league history to record 100 wins against a specific opponent, while they have also hit four or more goals in 12 separate Premier League fixtures against Everton – more than any other team has done against another.