Andy Murray was beaten by fellow veteran Fabio Fognini to suffer a disappointing first-round exit at the Italian Open.
Murray, fresh from claiming success at an ATP Challenger event in Aix-en-Provence on Sunday, had hoped to extend his five-match winning streak but instead saw his time in Rome end early to the 35-year-old home favourite.
A 6-4 4-6 6-4 defeat to the world number 130 halts the momentum of the Briton, who will now turn his attention to the French Open later this month.
Three-time grand slam winner Murray made the worst possible start in Italy with Fognini able to break him in his opening service game.
While the Scot did force a number of opportunities to break back at 3-2, he failed to seize the moment and his frustration boiled over later in the set with a debate occurring with umpire Mohamed Lahyani over a tight line call that saw Fognini go 5-3 up.
Fognini went on to clinch a 69-minute opener but quickly found himself 4-0 down in the second with Murray hitting his straps, albeit helped by a string of double-faults from his opponent.
A second-set wobble saw the veterans exchange breaks before Murray did force a decider with the encounter by that point edging past the two-hour mark.
Despite Fognini seemingly struggling physically during the second set, he found a new lease of life and took the initiative with an early break in the third.
Murray tried to keep pace with the Italian, who was mixing an array of baseline winners with unforced errors but a concern for the two-time Wimbledon winner occurred when he held his back during the seventh game of the third.
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It was not enough to stop the new world number 42 from continuing, and yet there would be no big fightback on this occasion with Fognini earning a fifth victory in nine meetings thanks to an ace after two hours and 55 minutes.
This latest first-round exit at an ATP 1000 event on clay, after similar losses in Madrid and Monto-Carlo, will give Murray around 10 days preparation before Roland Garros begins on May 22 where he is now unlikely to be seeded.
Elsewhere, fellow Briton Kyle Edmund was also knocked out in the Italian Open first round after he suffered a 6-1 6-3 defeat to Alexandre Muller.
World number 473 Edmund saw his struggles continue against a French player who broke into the top 100 last month.
Muller managed to wrap up the first set in 23 minutes in Rome and, while Edmund was able to push his opponent more in the second, the former Australian Open semi-finalist was consigned to a third consecutive loss.
Sabalenka goes the distance again to progress at Madrid Open
Aryna Sabalenka was forced to go the distance again at the Madrid Open as she battled past Robin Montgomery on Sunday.
Sabalenka, the reigning Madrid Open champion, needed three sets to win her second-round tie against Magda Linette on Friday, and the second seed did not have an easy ride against American Montgomery.
However, she eventually got over the line, triumphing 6-1 6-7 (5-7) 6-4 to tee up a last-16 meeting with Danielle Collins, who defeated Jaqueline Cristian 3-6 6-4 6-1.
Collins has now reeled off 15 straight wins, having won the Miami Open and Charleston Open in recent weeks, and has progressed to the last 16 in Madrid for the first time in her career.
The American said: "I've been doing so well the last couple of weeks, I think the girls know that when they come out and play me, they've got to go for it.
"That certainly was taking place the last two matches, some big shots that I've had to counter, and be able to react quickly."
Data Debrief: Sabalenka up there with Serena
Sabalenka has now won 14 of her 17 matches at the Madrid Open, which she won in 2023 and 2021.
Since the inception of the tournament, only Serena Williams (15) has won more of her first 17 matches at the event.
Alcaraz's pursuit for third straight Madrid Open crown continues by defeating Seyboth Wild
Carlos Alcaraz boosted his hopes of a third straight Madrid Open title as he comfortably beat Thiago Seyboth Wild to reach the fourth round on Sunday.
Back in his home country of Spain, Alcaraz eased to a 6-3 6-3 triumph to set up a fourth-round clash with Jan-Lennard Struff, whom he beat in last year's final.
The first six games of the opening set went to serve, but Alcaraz found a crucial break in the seventh and ninth games of the set to put him in pole position for victory, a lead he would not relinquish as he overcame being broken in the seventh game of the second set to seal his safe progression.
Holger Rune was a surprise casualty as the world number 12 was defeated 6-4 4-6 6-3 by Tallon Griekspoor, though world number eight Andrey Rublev eased through with a straight-sets win over Alejandro Davidovich Fokina.
Data debrief
With his triumph over Seyboth Wild at the Madrid Open, Alcaraz has now won 93.3 per cent of his games at the tournament. That is the highest win percentage of any player with at least 10 games played in a single ATP-1000 event since the format was introduced in 1990.
Against Seyboth Wild, Alcaraz won 27 of his 31 first-serve points, also recording 19 winners to his opponent's 10 as he dominated the contest on his way to victory.
Rybakina eases past Sherif to reach Madrid Open last 16
Elena Rybakina cruised past Mayar Sherif in straight sets to reach the last 16 of the Madrid Open on Sunday.
World number four Rybakina rarely looked like being troubled by Sherif, easing to a 6-1 6-4 triumph, winning 22 of her 26 first-serve points on her way to victory.
The 2022 Wimbledon champion broke Sherif's serve twice in the first set to gain control of the match, before holding her serve five times in the second to ensure victory.
Also into the last 16 in Madrid are Yulia Putintseva and Daria Kasatkina, who beat Caroline Dolehide and Anastasia Pavlyuchenkova respectively, both in straight sets. However, world number seven and reigning Wimbledon champion Marketa Vondrousova is out after she was upset by Mirra Andreeva, losing 7-5 6-1.
Data debrief
In reaching the Madrid Open last 16, Rybakina again showed her class on clay. Her victory over Sherif saw her become only the fourth player in the last 10 years to win 14 straight WTA matches on clay, alongside Serena Williams, Simona Halep and Iga Swiatek.
Additionally, Rybakina's 475 winners at WTA-1000 events in 2024 are 112 more than the next best, Danielle Collins with 363.
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