Casper Ruud was given a wake-up call ahead of the Australian Open as he was beaten by Laslo Djere in Auckland.
Ruud, who was beaten by Carlos Alcaraz in the US Open final last year, was the top seed in New Zealand but came unstuck in the round of 16 on Wednesday.
Djere came from behind to defeat the Norwegian world number three 3-6 6-3 7-6 (7-3) and seal his place in the quarter-finals, where he will meet Constant Lestienne.
In the process, Djere recorded his first career victory over a top-five opponent.
Ruud must now shrug off the disappointment and switch his focus to Melbourne, where he will be hoping to break his grand slam duck.
David Goffin overcame qualifier Christopher Eubanks in straight sets to tee up a last-eight tie with Richard Gasquet, while Jenson Brooksby received a walkover due to Diego Schwartzman's injury.
Unlike Ruud, second seed Cameron Norrie did make it through. The world number 12, who spent the majority of his childhood in New Zealand, enjoyed a homecoming as he saw off Jiri Lehecka 6-4 6-7 (4-7) 6-3.
Norrie is unbeaten in 2023, having beat Alex De Minaur, Taylor Fritz and Rafael Nadal while in action for Great Britain at the United Cup.
"Obviously, there were [some] nerves in me, coming back to New Zealand I wanted to play well in front of everyone, and Jiri's a great player," said the 27-year-old.
"So, it wasn't easy, and credit to him in that second set for playing a really good tie-break. He really took it to me, but I really enjoyed the time on the court."
There was also a shock at the Adelaide International 2, where top seed Andrey Rublev succumbed to wildcard Thanasi Kokkinakis.
Rublev hit back after losing the first set but Kokkinakis ultimately prevailed 6-4 3-6 6-3.
Second seed Pablo Carreno Busta also fell out, losing to Kwon Soon-woo, leaving third seed Karen Khachanov as the favourite after his straight sets defeat of Marc-Andrea Huesler.
Mikael Ymer, Jack Draper, Miomir Kecmanovic, Alejandro Davidovich Fokina and Roberto Bautista Agut all progressed.
Alcaraz continues fine form at Miami Open, Ruud eliminated by Van De Zandschulp
Top seed and reigning champion Carlos Alcaraz dished out a bagel as he continued his outstanding form with a straight-sets victory over Dusan Lajovic to ease into the Miami Open fourth round on Sunday.
Alcaraz, who triumphed at last week's Indian Wells Open, beat the 76th-ranked Serbian 6-0 7-6 (7-5) in one hour and 32 minutes.
The 19-year-old Spaniard hit 26 winners compared to Lajovic's eight, while Alcaraz also sent down three aces on a 75 per cent first serve percentage.
Alcaraz won the first frame to love in 32 minutes, registering his fourth career bagel at ATP Masters 1000 level, equaling the most by a teenager alongside Rafael Nadal.
The world number one will face 2023 Australian Open semi-finalist Tommy Paul in the fourth round after the American got past 20th seed Alejandro Davidovich Fokina 6-3 7-5.
Third seed and 2022 Miami Open finalist Casper Ruud blew a first-set lead to lose 3-6 6-4 6-4 to Botic Van De Zandschulp.
The Dutchman improved his head-to-head record against Ruud to 3-1 with his first-ever top five win, with the Norwegian left to lament converting only two of 15 break points.
Ninth seed Taylor Fritz progressed into the fourth round with a 6-4 6-4 win over Denis Shapovalov, improving his head-to-head record against the Canadian to 4-5. Fritz committed only eight unforced errors and did not face one break point.
Jannik Sinner maintained his excellent hard-court form with his 18th win this season on the surface, as he defeated Grigor Dimitrov 6-3 6-4 in one hour and 28 minutes. The Italian 10th seed will be Andrey Rublev in the next round.
Sixth seed Rublev needed less than an hour to get past Miomir Kecmanovic 6-1 6-2, while compatriot Daniil Medvedev advanced via a walkover against Alex Molcan due to a right hip injury.
Seventh seed Holger Rune cruised past Diego Schwartzman 6-4 6-2, while Finland's Emil Ruusuvuori got past Taro Daniel 6-3 7-6 (7-3).
Sabalenka marches into Miami Open fourth round, Andreescu continues run with Kenin win
Aryna Sabalenka needed just 68 minutes to dispatch Marie Bouzkova 6-1 6-2 in Sunday's third round of the Miami Open.
Sabalenka hit 26 winners in the victory and now has 250 at WTA 1000 level for the season, representing one of only two female players with more than 200 in 2023.
The world number two, who is the top seed in the tournament after Iga Swiatek's withdrawal, has now won 19 of her past 21 matches, with her only losses in that span to Elena Rybakina and Barbora Krejcikova.
She will get the chance to avenge that loss to Krejcikova next after the Czech Republic representative knocked out hometown star Madison Keys 7-6 (7-4) 6-3.
Former French Open winner Krejcikova registered her 10th WTA 1000 level win against Keys, becoming only the second player to achieve that this season.
Former Australian Open champion Sofia Kenin fell 6-4 6-4 to Canada's Bianca Andreescu, who continued her strong run after previously knocking out seventh seed Maria Sakkari and 2021 US Open champion Emma Raducanu.
In a serve-dominated match, 2019 US Open champion Andreescu sent down seven aces, maintaining 70 per cent first serve percentage.
Ninth seed and former Olympic gold medallist Belinda Bencic was eliminated 7-6 (10-8) 6-3 by 18th seed Ekaterina Alexandrova, who will take on Andreescu in the next round.
Marketa Vondrousova won her all-Czech matchup against 17th seed Karolina Pliskova, and their compatriot Petra Kvitova enjoyed a 6-4 7-6 (7-3) triumph over recent Monterrey Open champion Donna Vekic.
Romania's Sorana Cirstea made it seven wins from her past eight matches with a 7-5 6-1 result over Karolina Muchova, having knocked off fifth seed Caroline Garcia in the second round.
Varvara Gracheva ensured a strong day for the Russians with a 6-1 6-2 demolition of Magdalena Frech in a battle of two unseeded players.
Rybakina extends winning streak to 10, Potapova upsets Gauff in Miami Open third round
Last week's Indian Wells Open champion Elena Rybakina has extended her winning streak to 10 matches after defeating Paula Badosa 3-6 7-5 6-3 in Saturday's Miami Open third round.
Kazakhstan's Rybakina, who is also the reigning Wimbledon Champion and Australian Open finalist, got the better of Badosa for the second time during her current run, also eliminating her from Indian Wells.
The 23-year-old has to be considered one of the favourites to go all the way, having knocked off world number one Iga Swiatek and world number two Aryna Sabalenka to lift the trophy in California.
Rybakina will meet Belgium's Elise Mertens in the fourth round after she beat Croatia's Petra Martic 6-4 6-3.
Meanwhile, the biggest upset of the day was delivered by Russia's Anastasia Potapova, bouncing sixth seed Coco Gauff 6-7 (8-10) 7-5 6-2.
Potapova, who has never won a tournament above the WTA 250 level, will face China's Zheng Qinwen for a spot in the quarter-finals after her three-hour 5-7 7-6 (7-5) 6-3 triumph over Liudmila Samsonova.
Latvia's Jelena Ostapenko, the 24th seed, eliminated Brazilian 13th seed Beatriz Haddad Maia 6-2 4-6 6-3, while 20th seed Magda Linette of Poland knocked out Belarusian 14th seed Victoria Azarenka 7-6 (7-3) 2-6 6-4.
Unseeded American Clare Liu went down 4-6 7-5 6-4 against Italy's Martina Trevisan, but third seed Jessica Pegula will continue to fly the flag for the United States after advancing 6-1 7-6 (7-0) in her all-American showdown with Danielle Collins.
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