Steph Houghton has not been named in England's squad for the upcoming Euro 2022 tournament.
Lionesses manager Sarina Wiegman named her 23-woman squad on Wednesday, and included recently recovered Manchester City forward Chloe Kelly and Chelsea's Fran Kirby.
There was no place for former captain Houghton, though, who has not played since January after suffering an Achilles injury.
The Manchester City defender has appeared at five major tournaments for England and made 121 appearances so far in her international career.
Speaking at a media conference for the squad announcement at St George's Park, Wiegman confirmed: "It was a hard decision [to leave Houghton out], but she's just not ready to compete.
"We set a plan in place with her for her and she did everything she could do, we supported her as well as possible.
"She's in a very good place but just not ready to compete, I think. It's a matter of time, and we don't have that time.
"It was really hard. It's hard for every player we had to disappoint, but of course for such a big player with such a big impact on the England game, she did everything - but other players do everything too.
"Of course, she was very disappointed and I know she did everything to make it, so she wasn't happy, but she took the arguments I gave her and then we left it for now."
Wiegman named a provisional 28-woman squad in May, with Sandy MacIver, Niamh Charles, Katie Zelem and Lucy Staniforth also missing out on the final cut.
As the host nation, England kick off the tournament against Austria at Old Trafford on July 6.
England squad for Euro 2022: Mary Earps (Manchester United), Hannah Hampton (Aston Villa), Ellie Roebuck (Manchester City); Millie Bright, Jess Carter (both Chelsea), Lucy Bronze (free agent), Rachel Daly (Houston Dash), Alex Greenwood, Demi Stokes (both Manchester City), Lotte Wubben-Moy (Arsenal); Fran Kirby (Chelsea), Jill Scott (free agent), Ella Toone (Manchester United), Georgia Stanway (Bayern Munich), Keira Walsh (Manchester City), Leah Williamson (Arsenal); Beth England (Chelsea), Lauren Hemp, Chloe Kelly, Ellen White (all Manchester City), Beth Mead, Nikita Parris (both Arsenal), Alessia Russo (Manchester United).
Al-Khaleej 0-1 Al-Nassr: Ronaldo misfires on return as Laporte nets winner
Cristiano Ronaldo returned from suspension but failed to find the net as Al-Nassr secured a 1-0 win over Al-Khaleej on Saturday, with Aymeric Laporte coming up with the decisive goal.
Ronaldo was in action for the first time since being sent off for an elbow in a 2-1 Saudi Super Cup loss to Al-Hilal earlier this month, with his initial two-match ban being reduced to one on appeal.
He missed three good chances as Al-Nassr threatened to fall further behind runaway Saudi Pro League leaders Al-Hilal, but former Manchester City defender Laporte spared his blushes by nodding Marcelo Brozovic's deep free-kick into the bottom-left corner with 68 minutes gone.
Al-Nassr remain nine points adrift of Al-Hilal at the summit in spite of their win, with Jorge Jesus' team unbeaten through 28 games this season as they close in on a record-extending 18th title.
Data Debrief: Ronaldo misfires on return
Ronaldo was presented with the Saudi Pro League's Player of the Month award for March ahead of kick-off, having scored four goals in three league appearances last month.
However, his sights were off on Saturday as he failed to net despite three of the visitors' four big chances, as defined by Opta, falling his way. He led all players on the pitch for expected goals (1.27 xG), shots (five), shots on target (three) and touches in the area (nine) without reward.
Huddersfield all but relegated from Championship while League Two play-off spots decided
Huddersfield Town saw their relegation from the Championship all but confirmed after a 1-1 draw with fellow strugglers Birmingham City on Saturday.
The Terriers avoided a defeat that would have seen them relegated on Saturday, but even a win on the final day over promotion hopefuls Ipswich Town will not be enough unless they overcome a huge goal difference of 15 goals with Plymouth Argyle.
Birmingham remain in the other relegation place and now must beat Norwich City to stand a chance of staying up with Sheffield Wednesday, Plymouth and Blackburn Rovers also still in danger.
At the other end of the table, the Canaries dropped points in a 2-2 draw with Swansea City, leaving the door open for Hull City, who face Ipswich Town later today.
Leicester City seal automatic Premier League return
Leicester City are once more a Premier League team, having bounced straight back after relegation last season.
The Foxes secured automatic promotion without kicking a ball, as title rivals Leeds United lost 4-0 away to Queens Park Rangers on Friday.
Marti Cifuentes' Hoops side gave their fans a reason to cheer in their final home game of the season, and the emphatic win means they are now seven points clear of the relegation zone.
The Hoops boss told BBC Sport: "I came here, perhaps I was crazy thinking we could manage the great escape.
"The atmosphere has been unbelievable since I came here. Everybody thought tonight could be a special night to achieve our target.
"Big players deliver big performances and our players all did that tonight."
Defeat ensured only Ipswich Town can now finish above Leicester, meaning the Foxes will be back in the big time.
Ipswich, who have three games left to play, face play-off hopefuls Hull City on Saturday.
Speaking to BBC Sport, Leeds boss Daniel Farke said: "It's not in our hands any more [automatic promotion], we need to be honest.
"The race is not over. If Ipswich win the next two games then I will say congratulations, but if they don’t win them then we will have a lot to play for.
"As long as we have a chance, I’m far away from giving up."
Leicester could be crowned champions if they beat Preston North End on Monday and if Hull beat Ipswich.
The Foxes are looking to break the 100-point barrier, despite a wobble from Enzo Maresca's side in recent months.
After they had been so far ahead and top for all but two of the 176 days between 23 September and 17 March, an untimely dip in form handed Leeds and Ipswich hope.
However, while Leicester celebrate their promotion, they face the daunting prospect of starting next season with a points deduction, after they were charged by the Premier League with alleged breaches of the competition's Profit and Sustainability Rules (PSR).
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