Manchester City came from two goals to draw 2-2 with West Ham but Premier League title rivals Liverpool were handed hope thanks to Riyad Mahrez's late missed penalty.
The Reds celebrated an FA Cup triumph on Saturday and their chances of an unprecedented quadruple looked very much alive after Jarrod Bowen's double put West Ham 2-0 up at the break.
Yet Jack Grealish pulled one back for City who, despite more shaky defending, drew level when Vladimir Coufal headed into his own goal.
The stage looked set for Mahrez to seal a brilliant comeback win when Craig Dawson's foul on Gabriel Jesus was spotted by VAR, but Lukasz Fabianski made a strong save to keep Liverpool, who are four points back with a game in hand, in the title hunt.
City had control of possession early on but West Ham were dangerous on the counter and that tactic paid dividends in the 24th minute when Bowen beat the offside trap, rounded Ederson and coolly squeezed home.
A shocked City initially struggled to respond, though Jesus' dipping shot almost found the bottom-left corner in the 36th minute.
Yet West Ham struck again before the interval – Bowen engineering space on the edge of the box and drilling a crisp finish beyond Ederson.
City's response came inside four minutes of the restart, Grealish's volley deflecting in off Dawson.
Grealish brilliantly teed up a chance for Bernardo Silva that drew a superb stop from Fabianski, though shambolic defending might have cost City had Bowen or Michail Antonio being more clinical.
West Ham were made to pay with 21 minutes left – Coufal heading Mahrez's free-kick beyond Fabianski.
Aymeric Laporte diverted a goal-bound Bowen shot wide before City were awarded a golden opportunity to win it when Dawson brought down Jesus.
Mahrez stepped up but Fabianski guessed the right way, much to Pep Guardiola's frustration.
What does it mean? Going down to the wire
City would have moved six points clear with a win, and though Liverpool have two games remaining, they would have required a significant swing in goal difference.
As it is, Liverpool – who face Southampton on Tuesday – might well be relying on an old Anfield hero, as Steven Gerrard takes his Aston Villa side to the Etihad Stadium on the final day of the season.
West Ham, who said goodbye to Mark Noble as he came on for his final home appearance in the second half, are now sure of seventh place and European football next season and could still pip Manchester United to sixth.
Brilliant Bowen forever blowing bubbles
Bowen is the fourth West Ham player to score 10+ home goals in a single Premier League campaign after Tony Cottee in 1994-95, John Hartson in 1997-98, and Paolo Di Canio in 1999-00, while only Harry Kane (26) has scored more goals in all competitions amongst Englishmen in the Premier League this season than the Hammers' winger (18).
Mahrez fluffs his lines
Mahrez has been reliable from the penalty spot this season and is enjoying a fine campaign, but in a clutch moment the Algeria winger failed to deliver. His penalty was struck hard, but too close to Fabianski, who did react well to make the save to his left.
What's next?
City round off their season against Villa, while West Ham visit Brighton and Hove Albion in their final game.
FC Cincinnati v Colorado Rapids: Armas wants players to enjoy rise
Chris Armas says his Colorado Rapids players deserve to enjoy their meteoric rise up the MLS standings, and he is confident they will not get carried away ahead of their trip to FC Cincinnati.
Colorado sit fourth in the Western Conference with 15 points from nine games, winning three of their last four after an inconsistent start to the year.
They benefitted from two own goals as they beat FC Dallas 2-1 last time out, and Armas has no issue with his players enjoying their place in the standings, particularly given they finished rock bottom of the West in 2023.
"I see the boys looking at the TV where we have the standings posted, and they see that we're climbing, so it's all good stuff," Armas said.
"From day one the message that I preached is that everything we do will be based on hard work and that we will never get too low on ourselves.
"We don't get too high, the boys are realistic. That part's not that hard and our group is hungry and looking to improve every day."
Supporters' Shield holders Cincinnati have had an up-and-down start, going unbeaten through their first five games of the year before suffering back-to-back defeats against the New York Red Bulls and CF Montreal (both 1-2).
However, Pat Noonan's men bounced back with a statement 2-1 victory over Atlanta United last week, and defender Matt Miazga hopes that result will be a turning point.
"I look at everybody and I'm like, 'Alright, I see in his face, I see in his face. We want it,'" Miazga said.
"We all realised we are a top team, with big personalities, big characters, and it's time to show up in big moments."
PLAYERS TO WATCH
FC Cincinnati – Luciano Acosta
Acosta assisted Cincinnati's equaliser against Atlanta last Saturday before scoring the winner two minutes later.
That was Acosta's 13th regular-season match with a goal and an assist since the start of the 2022 season, three more than any other player in MLS has managed during that time.
Colorado Rapids – Djordje Mihailovic
Mihailovic has created at least twice as many chances as any other Colorado player in MLS this term (16), with Keegan Rosenberry and Sam Vines creating eight apiece.
He also has two goals and one assist to his name, while only Rafael Navarro (16) has bettered his 10 successful dribbles among his team-mates.
MATCH PREDICTION – FC CINCINNATI WIN
Cincinnati earned their first win over the Rapids last May, triumphing 1-0 on the road. The Rapids had won the first two meetings between the sides, including a 2-0 victory on their only previous trip to Cincinnati.
The Rapids also enter Saturday's game having won successive regular-season matches for the first time since September 2022, eyeing their first three-game winning streak since August 2021.
However, Cincinnati ended their poor run by beating Atlanta last time out and have, despite some underwhelming performances, only lost two of their nine league games this term (four wins, three draws). On home soil, the Supporters' Shield holders are favourites.
OPTA WIN PROBABILITY
FC Cincinnati – 49.3%
Colorado Rapids – 23.3%
Draw – 27.4%
Guardiola insists three teams still in title hunt despite Liverpool slip-up
Pep Guardiola insists Liverpool remain in the Premier League title race, despite the Reds losing further ground on Arsenal and Manchester City in a dramatic few days at the summit.
Liverpool suffered a surprise 2-0 defeat to Merseyside rivals Everton on Wednesday, a result which meant they failed to close the gap to Arsenal after the Gunners thrashed Chelsea 5-0 on Tuesday.
While Jurgen Klopp's men couldn't respond to the Gunners pulling clear, City did on Thursday, with Phil Foden scoring twice in an emphatic 4-0 win over Brighton at the Amex Stadium.
One point behind Arsenal with a game in hand, City know five wins from their five remaining matches will seal an unprecedented fourth successive English top-flight title.
However, Guardiola expects further twists and turns in the coming weeks.
Asked if Liverpool were still in contention after City's win, Guardiola told Sky Sports: "Yeah. Many things can happen.
"What happened with Liverpool, losing to Crystal Palace and Everton, can happen to us. It can happen to Arsenal. No-one is safe. We have to rest. Now it is just about recovering for the next one.
"We have been here in the past but being here in the past doesn't mean it is going to happen. We have to do the things to make it happen."
City's comprehensive win – in which Kevin De Bruyne scored his first headed goal in the Premier League – saw them cut Arsenal's goal difference advantage to eight goals.
However, Guardiola believes it will be tough for City to close that gap, saying: "It is difficult to cut. The margin is so big. They score a lot of goals and don't concede.
"The main thing is to win the games. We have five games left and they are tough ones – it's a lot of games. We'll take it one game at a time."
Foden's first goal against Brighton – a deflected free-kick – saw him become just the third player to score 50 top-flight goals under Guardiola while aged 23 or younger, after Erling Haaland and Lionel Messi.
Foden is the favourite to be named Premier League Player of the Season, and while Guardiola believes he should be in contention, he says his player is more concerned with team honours.
"For sure, but he wants to win the Premier League," Guardiola said when asked if Foden deserved individual honours. "His influence in the final third was better than in the last two or three games. Today he was more calm, his decision-making was good and to score goals is always good."
Foden: De Bruyne the best in the Premier League
Phil Foden hailed Manchester City team-mate Kevin De Bruyne as the Premier League's best player after the pair both netted in the 4-0 win over Brighton and Hove Albion.
De Bruyne opened the scoring in Thursday's contest at Amex Stadium before Foden took over with a couple of goals of his own before half-time.
Julian Alvarez rounded off the scoring just after the hour in a one-sided contest as an Erling Haaland-less City moved to within a point of leaders Arsenal with a game in hand.
Belgium international De Bruyne now has four goals and six assists in just 13 league appearances for City this season.
Speaking to Sky Sports News after the win over Brighton, Foden said: "I think when he is at it, he is the best player in the Premier League."
Foden's first goal came via a deflected free-kick that he himself won, although replays showed he slipped rather than being fouled.
The England international doubled his personal tally with a composed finish after Brighton were caught in possession at the back.
Asked about playing more centrally, Foden said: "I have always said that I see myself there. This year I have moved inside and it has helped me massively.
"I enjoy it in the middle. It's where I want to be. At the moment, I am just enjoying my football and playing with freedom."
De Bruyne had earlier opened the scoring with a brilliant opener - his first headed goal for City in the Premier League - as City made it 30 games unbeaten in normal time across all competitions.
Alvarez then went on to round off the scoring in a game that not only saw the reigning champions close the gap on Arsenal, but also narrow the goal difference margin to eight.
"It was a good game," De Bruyne said. "I think we played really good in the first half and every game is a lot of pressure. All we can do is prepare as we did today and win the game that is in front of us.
"We just want to win game-by-game and push for the title. We don't get ahead of ourselves. Now the next game is coming quickly. Try to recover and we go again."
Kyle Walker assisted the De Bruyne and Alvarez goals - the first time the defender has set up two goals in a single Premier League game in what was his 390th appearance in the competition.
Reflecting on his rare headed goal, De Bruyne said: "It doesn't happen too much. Kyle gave a good cross and I think the only way I could reach it is by jumping to it. I will take it but it's not something I am good at."
City have rather ominously won four Premier League games in a row and travel to strugglers Nottingham Forest next up at the weekend, knowing victory in their remaining five games will secure an unprecedented fourth straight title.
"I trust my team. All respect to Liverpool and Arsenal, they are amazing," De Bruyne added. "Arsenal are doing what they need to do and we are also needing to do it. Work hard and be humble enough to keep pushing."
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