Veteran striker Zlatan Ibrahimovic will miss Milan's Serie A game with Empoli on Wednesday due to a knee injury.
Milan head coach Stefano Pioli confirmed the 40-year-old Swedish forward's absence along with Rafael Leao leaving him short of attacking options.
Ibrahimovic has netted seven league goals this term for Milan, who have only managed one point from their past two games, slipping four points behind leaders Inter in the league
"[Leao] won’t be there tomorrow, he’ll be back against Roma. Ibrahimovic won’t be there tomorrow because of an overload on his knee," Pioli told reporters.
Pioli was more positive about captain Alessio Romagnoli's prospects of playing, along with Theo Hernandez after illness amid an injury crisis at the club, without Simon Kjaer, Davide Calabria, Ante Rebic and Pietro Pellegri also out.
"Theo has become more complete, now he does the defensive phase better too," Pioli said.
"He gives us a lot on the attacking side. He’s better, I hope he’ll be in top condition tomorrow."
Pioli added that he paid little attention to the criticism levelled at his side lately, following Sunday's 1-0 home loss to Napoli who leapfrogged them into second spot.
"I read little, but some things are useful to improve," he said. "Against Napoli, Milan played a good match.
"We make mistakes that are not allowing us to get results, clearly we need to do something more. We need more quality."
Pioli added: "When results don’t come it’s right to be less calm, but also more determined.
"We have to think about tomorrow’s game, we want to get back on track after a home defeat. We wanted to score more points in the first half of the season than we did last year. It won’t be possible, but we want the three points tomorrow."
Milan have 39 points after 18 games, but have only collected eight points from their past seven league games.
Nashville SC v San Jose Earthquakes: ‘A win would change everything’ - Godoy
Anibal Godoy insists that Nashville are already looking at their game against San Jose Earthquakes on Saturday as a must-win.
Nashville have won just once in the MLS this season and sit in 14th place in the Eastern Conference after a run of four without a win.
The Earthquakes, meanwhile, are bottom of the Western Conference having lost eight of their matches and recording just one win.
Godoy is aware of how their poor start to the season could affect their playoff hopes later down the line but is confident that Nashville can turn things around.
He said: “For us, it's an important week. It's a day we have to win, or we'll start to feel the pressure from other teams as they start to separate in the table.
“This league is long but if we want to get to the playoff you have to win games early on, especially at home.”
Liverpool agree compensation deal for Slot
Liverpool and Feyenoord have reached an agreement in principle over a compensation deal for Arne Slot to become the Reds’ manager next season, according to widespread Dutch media reports.
The Dutchman is reportedly poised to take over from Jurgen Klopp, who announced in January that he would be leaving the club at the end of the campaign.
Slot led Feyenoord to their second Eredivisie title last season after taking over the club in 2021.
It is believed that he topped the list of Liverpool’s favoured candidates due to his attacking playing style and ability to develop players.
Former Liverpool midfielder, Xabi Alonso, who led Bayer Leverkusen to their first Bundesliga title, and Sporting CP’s Ruben Amorim were also reported contenders to take over from Klopp.
Slot had already confirmed his interest in managing in the Premier League, both earlier this week and previously when he was linked to Tottenham in 2023.
QPR 4-0 Leeds United: Shock loss for Farke's men seals Leicester's promotion
QPR thrashed Leeds United 4-0 in the Championship on Friday, ensuring Leicester City booked their promotion straight back to the Premier League.
Ilias Chair was the star for the Hoops as he scored the opener and assisted two more goals to ensure QPR will stay in the Championship for another season.
Lucas Andersen, Lyndon Dykes and Sam Field also got their names on the scoresheet in an emphatic win for Marti Cifuentes' side.
Leeds' heaviest defeat of the season was a huge blow in the race for an automatic promotion spot, with Ipswich Town just one point behind them in third place with two games in hand going into their away clash against Hull City on Saturday.
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