Argentina can clinch top spot in Group A as they aim to maintain their unbeaten run under Lionel Scaloni against a Bolivia side already certain of an early Copa America exit.
The format of the 2021 tournament means just one team from each section misses out on the last eight, though the final matches are still pivotal as nations jostle for positions in the final standings.
Bolivia's exit was confirmed with a 2-0 reverse against Uruguay last time out, another blank in front of goal meaning Cesar Farias' side have managed to score just once in three outings so far.
Argentina have also found it tough going in attack, despite the presence of the talismanic Lionel Messi. Following a 1-1 draw with Chile in their opener, they have recorded back-to-back 1-0 triumphs over Uruguay and Paraguay.
Those results mean head coach Scaloni has not seen his team lose in his previous 16 games. His last defeat in the job came in the previous edition of the Copa America, as they were knocked out by rivals Brazil in the 2019 semi-finals.
A potential rematch appears unlikely until the final this time around, with Brazil winning Group B. Argentina know a victory in Cuiaba will be enough for them to do the same ahead of the quarter-finals.
Scaloni has a decision to make over whether to rest Messi, who has played every minute in the competition so far.
While the Barcelona superstar just recently turned 34, he may want to be involved from the start as he looks to win his 148th international cap, which would move him out of a tie with Javier Mascherano to sit alone at the top of the list for Argentina appearances.
Those in danger of receiving a suspension with another yellow card on Monday are likely to be left out, among them Lautaro Martinez, Leandro Paredes and Giovanni Lo Celso.
PLAYERS TO WATCH
Argentina - Alejandro Gomez
'Papu' Gomez arrived late to international football but helped make up for lost time in his previous outing with his first goal in a competitive fixture for Argentina. He struck in the 10th minute against Paraguay, while he also completed 88.2 per cent of his attempted passes in the opposition half before being substituted. Did he do enough to keep his place, though?
Bolivia - Carlos Lampe
Goalkeeper Lampe has been a rare positive for his team at the Copa America, making the most saves per game (eight) among those to have played in two or more fixtures. Even with Argentina potentially resting players, Bolivia's last line of defence may well be busy again as they prepare to say farewell to this year's Copa.
KEY OPTA FACTS
- This will be the 10th meeting in the Copa America at a neutral venue, with Argentina never previously losing in such contests (W9 D1). However, Bolivia have won twice when serving as competition hosts, in 1963 and 1979.
- Scaloni is unbeaten in his last 16 managerial games in all competitions, his best run since taking charge of Argentina (W9 D7).
- After five unbeaten games in the Copa America with Venezuela, Cesar Farias has lost the last four; one for Venezuela (semi-final in 2011) and three for Bolivia (all this year).
- Argentina are the team with the most goals scored in the first 15 minutes of their games (two), with all of their goals scored in the first half of games (three, same as Ecuador).
Coventry City 2-3 Hull City: Tigers win five-goal thriller to keep play-off hopes alive
Hull City kept their hopes of gatecrashing the Championship play-offs alive with a thrilling 3-2 win over beaten FA Cup semi-finalists Coventry City on Wednesday.
Noah Ohio scored the winner with his first touch after coming on as a second-half substitute as Hull moved within three points of sixth-placed Norwich City with two games to play.
Coventry, meanwhile, saw their own hopes of returning to Wembley Stadium for a second successive play-off final all but ended, as they sit six points further back with three matches remaining.
Three days on from their remarkable comeback against Manchester United, the Sky Blues twice fought back to level things at Coventry Building Society Arena. Jaden Philogene's shot squirmed under goalkeeper Bradley Collins to put Hull ahead 31 minutes in, but Kasey Palmer levelled within five minutes with a stunning free-kick.
Hull went back ahead in controversial circumstances on the stroke of half-time, Liverpool loanee Fabio Carvalho converting from the penalty spot despite replays showing Joel Latibeaudiere's foul on Liam Delap took place outside the area.
Mark Robins' men again dragged themselves back into the game as Bobby Thomas headed Jay Dasilva's cross in just before the hour mark, but it was Liam Rosenior's visitors who found a winner.
Thomas went from hero to villain as his poor back pass sold Collins short, and Ohio got a toe to the ball to score the winner, keeping Hull's hopes of Premier League football intact.
Van Dijk: Liverpool have 'no chance' in title race after derby defeat
Virgil van Dijk conceded Liverpool might be out of the Premier League title race after they suffered a surprise 2-0 defeat to Everton in Wednesday's Merseyside derby.
Jarrad Branthwaite and Dominic Calvert-Lewin scored in either half to give the Toffees their first win over Liverpool at Goodison Park since 2010.
Liverpool struggled to find a way through the Toffees' defence despite dominating for long periods, and the Reds' captain says they will not outlast Arsenal and Manchester City without major improvements.
Speaking to Sky Sports, Van Dijk said: "If we play like today, then we have no chance to consider ourselves in the title race.
"We have to just focus on the next game and that will be a tough one anyway, so we will see.
"We're very disappointed, in so many ways. I think everyone has to look at their own performances. Did they really give everything, and do they really want to win the league?
"We're still fighting and there are still games after tonight, but if we play like we did overall in the game today – not winning challenges and giving the referee a chance to give free-kicks like he did many times, then you have no chance to win the title."
Howe: Newcastle performance in Palace defeat 'way off' Spurs win
Eddie Howe admitted Newcastle United's performance in the 2-0 loss at Crystal Palace on Wednesday was "way off" the one that saw them thump Tottenham in their previous game.
Howe's men hammered Spurs 4-0 in their last match, but they never got close to matching the attacking verve from that outing and a Jean-Philippe Mateta double condemned the Magpies to defeat at Selhurst Park.
Newcastle didn't even manage a shot on target until the 87th minute, accumulating just 0.42 xG (expected goals) as the likes of Alexander Isak and Anthony Gordon struggled to make an impact.
Only against Manchester City in August (one) have Newcastle recorded fewer shots on target in a Premier League game this season than their two against Palace, and Howe was critical of his team's display in the loss, one that all but ends their hopes of finishing in the top four.
"[It is a] bad day for us," Howe told Newcastle's club media.
"I thought we were disappointing today, especially in the first 60 minutes. We were way off our levels against Tottenham and our best levels.
"I thought technically we didn't deliver a good performance, and out of possession I don't think it was a particularly good performance either."
Newcastle were unlocked twice for Mateta to score by a Palace side who themselves only generated 0.88 xG.
Howe was left frustrated by the manner in which his side conceded, adding: "I think we'll be disappointed with our performance technically today, and that's probably epitomised by the two goals where we're disappointed with how we've given them the ball in those situations and then how we defended.
"I think the goals sum up aspects of our performance where there was some good, lots of moments that could have led to opportunities, but we were slow to shoot around the box," he said.
The defeat, combined with Manchester United's 4-2 win over Sheffield United, means Newcastle drop to seventh, while eighth-placed West Ham are two points behind with a game in hand.
Newcastle have now lost eight of their last 11 Premier League away games, while they have lost on four occasions in London in the league this term, only doing so more times in a Premier League season in 2000-01 and 2005-06 (both five).
It's been a disappointing season for Howe and his side, especially compared to the heroics of last term when Newcastle finished in the top four, and the Magpies boss knows there's work to be done to get back to those levels.
"It's a day that we have to take our punishment, deal with it, and then try and improve," Howe continued. "It's frustrating because we know we're capable of much better."
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