Manchester United matched their own record for the biggest home win in Premier League history as Southampton suffered the unprecedented ignominy of 9-0 defeats in consecutive seasons.
Ralph Hasenhuttl's men saw their outing at Old Trafford unravel from the moment Alexandre Jankewitz was shown a second-minute red card for an ugly lunge on Scott McTominay.
Aaron Wan-Bissaka began the rout and efforts from Marcus Rashford and Edinson Cavani either side of a Jan Bednarek own goal made it 4-0 at half-time.
Anthony Martial and McTominay made it 6-0 inside the final 20 minutes before a Bruno Fernandes penalty, Martial's second and a closing goal from Daniel James left Southampton – who also saw Bednarek sent off – in an unsightly heap.
From nine goals to nine men, Arsenal had David Luiz and Bernd Leno dismissed as they lost 2-1 at Wolves.
That scoreline was repeated in victories for Sheffield United and Crystal Palace that could have repercussions at the bottom of the table.
Manchester United 9-0 Southampton: Record-equalling joy and despair at Old Trafford
James' goal deep into stoppage time meant United won 9-0 for the first time since thrashing Ipswich Town in March 1995. It is only the third instance of this scoreline in the Premier League, following Southampton's thrashing on home turf against Leicester City in October 2019.
This fixture is not always anything like as kind to United. In fact, they have won home and away against Saints for the first time since 2012-13 – the last time they lifted the title.
Southampton's fourth consecutive Premier League defeat is also their biggest ever away loss in any competition.
United's efforts to share the goals around, with only Martial hitting a brace, means they are the second side to have seven different scorers in a Premier League match following Chelsea against Aston Villa in December 2012.
Ole Gunnar Solskjaer has seen his side utterly transform their home performances. They won only one of six at Old Trafford at the start of this league season, scoring three times. A run of four wins out of five, with one defeat, has yielded 19 goals.
The late flurry was aided by Bednarek adding a red card to his own goal, while it could have been so different were it not for Jankewitz's rash tackle. The teenager is the first player to be sent off on his first Premier League start since Serge Aurier for Tottenham in September 2017 and the fourth man to be dismissed inside two minutes in a Premier League game.
Wolves 2-1 Arsenal: David Luiz and Leno leave Arteta's men short
Arsenal took a deserved lead at Molineux through Nicolas Pepe, who now has three goals in his past four league starts – as many as he managed on his previous 16 starts.
Mikel Arteta says he will appeal David Luiz's punishment but the Brazilian defender's foul on Willian Jose means he has been sent off three times and conceded six penalties since his Arsenal debut in August 2019, more than any other player in the division during that time.
Ruben Neves converted from the spot before fellow Portugal midfielder Joao Moutinho hammered in a fabulous 30-yard effort. Very much a collectors' item, it was the first home goal of his Wolves career at the 61st attempt.
When Leno charged from his area to handball in a wretched misjudgement, Wolves' first league double over Arsenal since 1978-79 was virtually assured and the Germany international became the second Gunners keeper to be sent off in the Premier League – and the first since David Seaman against West Ham back in 1993.
Whether largely down to indiscipline or misfortune, Arsenal have been shown nine red cards since Arteta took charge on Boxing Day 2019 – six more than any other side.
Sheffield United 2-1 West Brom: Blades sharpen survival chances
Bottom club Sheffield United are now just a point behind West Brom in 19th, even though they fell behind to Matt Phillips' close-range finish before half-time.
Phillips has now found the net in each of the past 13 seasons in English league football, a run that goes back to 2008-09.
Jayden Bogle brought the hosts level before captain Billy Sharp stepped up to net another crucial goal.
Since Chris Wilder's first game in charge of United in August 2016, Sharp has scored 76 goals in all competitions – 44 more than any other Blades player during that period.
Sam Allardyce's much-vaunted reputation for making his teams hard to beat is not doing West Brom much good at the moment. The Baggies have conceded 26 goals in nine Premier League games under the ex-England boss, as many as they let in during 13 matches under Slaven Bilic this term.
Newcastle United 1-2 Crystal Palace: Eagles soar clear of trouble
Newcastle remain eight points above the drop zone but are now seven shy of Palace, despite enjoying a dream start.
Jonjo Shelvey's long-ranger after 71 seconds was the quickest goal the Eagles have conceded in a Premier League match since Ian Taylor scored for Aston Villa inside a minute in March 1998.
Roy Hodgson's side had not won away from home after conceding first since overcoming West Ham in October 2019, drawing two and losing 12 of such games since.
But Jairo Riedewald's venomous hit saw them level in style as he ended a run of 13 games without a goal in the Premier League.
Gary Cahill then became Crystal Palace's oldest ever goalscorer in the Premier League at 35 years and 45 days. He is also the oldest Englishman to score in the Premier League at St James' Park since Alan Shearer last did so.
Dewsbury-Hall: Maresca will surprise people at Chelsea
Kiernan Dewsbury-Hall believes new Chelsea manager Enzo Maresca will "surprise a lot of people" when they watch the Blues this season.
The Italian led Leicester City straight back to the Premier League as Championship winners in his only season in charge and succeeds Mauricio Pochettino at Stamford Bridge.
The Foxes topped the second division table with 98 points, with Dewsbury-Hall a key figure in his squad as he netted 12 goals and provided 14 assists last season – his best tally in a single campaign.
Dewsbury-Hall was also named Leicester's Player and Players' Player of the Year.
The midfielder made the switch to West London earlier this month for £30million and is confident that Maresca will have Chelsea challenging for trophies in no time.
"The manager was a big catalyst in wanting me to come," Dewsbury-Hall told BBC Sport.
"I knew from Leicester, a club that went down and had a lot of problems, how he managed to galvanise that if everyone manages to buy into the system.
"I genuinely think in a short space of time we can be pushing for minimum top four - but more than that.
"He may be unknown for a lot of people, but he is top, top level. He will surprise a lot of people."
Chelsea's pre-season got off to a frustrating start as they were held to a 2-2 draw by League One side Wrexham in Maresca's first game in charge on Wednesday.
Dewsbury-Hall did not play in that match but is training with the squad in the United States and could feature in their next outing against Celtic on Saturday.
The 25-year-old is confident the manager's tactics will come across soon, with the players buying into his style.
"We've only been doing it for two or three weeks, but the combination plays are really quick and tidy," he added.
"That's after two weeks. I remember he said to us at Leicester after six months or a year, there might be teething problems at the start, but it will improve.
"Within the first week at Leicester, I was convinced this was top, top level. I felt a bit stupid; I thought I knew a lot about football, but he was teaching me things on a daily basis that I didn't really know before. He has an aura, he can be strict, or gentle and soft - he has both sides.
"I am getting the same feedback here with the lads. They've bought into it here from minute one which is exciting. With a system and philosophy, you need everyone to buy in because, if they do, you can really achieve something."
Ederson slams reports of rift with Man City backup Ortega
Ederson has hit out at reports of a rift between himself and fellow Manchester City goalkeeper Stefan Ortega.
The Brazilian was substituted after suffering a fractured eye socket in City's penultimate game of the Premier League season, a vital 1-0 win over Tottenham.
Ortega replaced him and made a brilliant save to deny Son Heung-min as City maintained their slender lead over Arsenal at the top of the table, sealing an unprecedented fourth straight title by beating West Ham five days later.
Ortega was widely lauded for his role in that triumph, and an article published by The Athletic this week suggested Ederson took issue with that praise.
However, the goalkeeper – who missed the Copa America as a result of his injury – has now moved to shut down those suggestions with a post to his Instagram story.
"I would like to clarify that the note published by The Athletic yesterday, referring to my alleged dissatisfaction with a co-worker, is completely false," he wrote.
"The alleged day reported was, without a doubt, one of the most difficult days of my career, when I suffered a fracture that prevented me from playing in the final stretch of the season and, consequently, from representing my country in the Copa America.
"At the time of the injury, my only thought was to continue in the match, defending City in the fight for the title.
"But the emotion of the match would be greater than the reality and, inevitably, I would not be able to continue as I would have liked due to the damage it caused, completely blocking my field of vision. I remain focused on preparing for the season."
Ederson has been linked with a transfer in recent days, reportedly attracting interest from Saudi Pro League clubs.
Slot's Liverpool success will be measured by trophies, says McAllister
Gary McAllister says Arne Slot must be prepared to aim high by targeting trophies if he is to be successful with Liverpool.
The Dutchman is set to begin his first season in charge of the Reds after being appointed as Jurgen Klopp's successor in May.
Liverpool enjoyed a trophy-laden spell under the German, winning their first-ever Premier League title, as well as a Champions League, a Club World Cup, a Super Cup, an FA Cup and two EFL Cups.
However, Slot was no stranger to success while at Feyenoord, leading the team to the Eredivisie title in 2022-23 before lifting the KNVB Cup in April during his final season with the club.
McAllister, who won five trophies in the two years he spent at Liverpool, says Slot's success will be determined by the silverware he collects.
"Liverpool is a club that's synonymous with winning, and when you don't win you fail," McAllister told Stats Perform.
"When there's a new management team, you're given a little bit more time, but the facts are Liverpool's target, I felt, and as a player that played against them for most of his career, the targets that Liverpool set, you go into every tournament looking to win it.
"You try to win every game and that's the expectation of the club and that's what makes it a very special club."
Klopp spent nine years at Liverpool, breaking club records as his team pushed for trophies on a regular basis.
The Reds enjoyed a club-record 68-match unbeaten run at Anfield over nearly four years in the Premier League between April 2017 and January 2021.
Klopp also oversaw three of the four most prolific seasons in Liverpool's history, including the club-record total of 147 goals scored in 2021-22.
Slot has admitted he has "big shoes to fill", but McAllister believes the 45-year-old will be able to live up to the high expectations left behind by Klopp.
"Arne arriving at the club, following Klopp, realising that it's such a difficult job anyway, but to follow somebody who's done particularly well at the club over an eight, nine-year period is going to be tough, and I don't think the new manager is under any illusions," he added.
"What I would say is he's a man that seems to be a very strong character, good personality, and he's just got to come in and be his own man and trust what he does.
"He's done very well in his previous managerial career and coming to Liverpool I feel is a natural progression in the levels of the game that he's worked at.
"So, everybody at the club will be deeply backing him and be right behind him, he'll have amazing support."
Liverpool's first pre-season game under Slot ended in a 1-0 defeat to Preston North End last week before the players flew out to the United States for a three-game tour.
They are also only one of two Premier League clubs yet to conduct any business in the transfer window so far, but McAllister urged fans to be patient with Slot while he gets settled in his new role.
"Whenever there's a change at a club, I think the fans have got to realise that it does take time for a new manager, a new coaching group to come in and get their ideas over to the players," he said.
"There's got to be a modicum of patience, but at Liverpool, expectation levels are very, very high and sometimes, in professional soccer, in elite soccer, patience is something that most managers don't get.
"As much as the fans have got to be aware that everything is new and there are new ideas, Arne and the players will want to get off to a quick start.
"I feel that this pre-season tour is going to help them start the season against Ipswich Town very strongly. I feel the games that they've got here in the US, here in Pittsburgh against Betis, and then we go to play Arsenal and Manchester United, the build-up is pretty good."
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