Mikel Arteta questioned the decision to send off David Luiz after the defender was one of two Arsenal players to be dismissed in a 2-1 defeat at Wolves.
Arsenal appeared set to go in at half-time deservedly ahead following Nicolas Pepe's opener, only for David Luiz to concede a penalty following a challenge on Willian Jose.
The Brazilian centre-back was shown a red card by referee Craig Pawson following a VAR check, though Arteta insisted he could not see any contact after studying replays of the incident.
Ruben Neves converted from the spot before Joao Moutinho's long-range strike put the hosts ahead shortly after the break, with any hopes of a fightback disappearing for Arsenal when goalkeeper Bernd Leno was given his marching orders for handling the ball outside the area.
For Arteta, though, it was the David Luiz call that left him frustrated, particularly after his side had played so well up until that crucial moment in the contest.
"First of all, I have to say that I'm proud of my team, the way we played and the way we dominated the first half," Arteta told the media.
"We should have been 3-0 or 4-0 up. We didn't do that, though, and we put ourselves in a really difficult position by conceding the goal and going a man down.
"I have seen the replay 10 times from five different angles and I cannot see any contact. I would like to see if VAR has a different angle. I'm expecting to see something and I'm not seeing anything.
"We were really animated at half-time because we really wanted to win the game. The boys were so convinced to go out there and have a real go.
"We didn't concede any chances but Moutinho scores a worldie and it's 2-1. Then, when Bernd comes out and hits the ball with his hand, we're down to nine men and almost impossible to win the game."
Since making his league debut for Arsenal in August 2019, David Luiz has picked up three red cards and conceded six penalties, more than any other player in the competition in both categories.
Arteta - who has seen his team shown nine Premier League red cards since taking charge, six more than any other top-flight team - admitted the result was tough to take.
"The way we lost the game really hurts. It's painful," he said.
"I have to take the positives as well, which is the way we played against this team that is very difficult to attack, the amount of chances we created. But we leave the ground and have zero points and have lost two important players.
"It's hard enough to win football games in this league. There's nothing we can change. It was a big decision, if they got it right and can justify they got it right, I'll put my hand up and apologise.
"The only thing I'm saying is that I’m sitting here and I cannot see any contact. That's really, really frustrating, because it's a big, big moment in the game."
Asked if Arsenal may issue an appeal against the red card for David Luiz, Arteta replied: "Where I’m standing now, I'd say yes – let's go straight away. But I don't know, we will have to speak to the legal team at the club and decide if it is the best thing."
Runar Alex Runarsson came on to take over from Leno in goal, with recent recruit Mat Ryan ruled out with a muscle issue. Arteta revealed he is hopeful the Australia international can be fit in time for Saturday's trip to Aston Villa.
'Now we think about what's next' – Messi switches focus to MLS Cup
Lionel Messi set his sights on MLS Cup success after leading Inter Miami to the Supporters' Shield.
Messi scored twice as Miami beat the Columbus Crew 3-2 on Wednesday and secured the Supporters' Shield for the first time in their history.
The regular-season points record in MLS is also on the cards for Miami, though they must win their remaining two games before the playoffs in order to surpass the tally of 73 set by the New England Revolution in 2021.
And Messi is now focused on the next task at hand.
"We suffered until the end," Messi told MLS Season Pass. "It shows what this team is about."
In quotes reported by BBC Sport, Messi said: "The first objective has been achieved and now we have to think about what's next.
"The first round is three games but then it's one game and anything can happen. But we have the great advantage of playing all the games at home, which is what we were looking for. We are very strong at home."
Messi's sentiment was echoed by Miami coach Gerardo Martino.
He said: "We reached the objective.
"We have good moments in the game, suffering moments in the game, and it happens to everybody to be able to achieve something.
“Now we can say, with our results and our game, we’re able to think that we've gotten to a higher level. I am not one of these people that strictly goes by results, that chases results. We are in a construction period and a building period, something similar.
"We are in the process of creating that thing, a franchise that thinks of more and that gets to win more than lose. And this is very essential, this is very important, that we've changed, and done so in a very short time. With today, we've got 20 wins in the league, and at other times we couldn't have thought of that. To change that dynamic for us is very important."
Simeone takes positives but Oblak slams 'pitiful' Atletico performance
Jan Oblak hit out at a "pitiful" performance from Atletico Madrid after their 4-0 loss to Benfica in the Champions League.
Benfica recorded their joint-biggest victory in a Champions League home match (alongside 5-1 vs Club Brugge in March 2023), as Atletico suffered their heaviest ever defeat to Portuguese opposition in the competition.
Atletico had only four shots, failing to get any of them on target, and mustered just 0.24 expected goals (xG).
Benfica, on the other hand, had 19 shots and accumulated 4.46 xG.
While Diego Simeone believed there were positives to take, Oblak, who made six saves to keep the scoreline from getting even more humiliating, was far more scathing of Atletico's display in Lisbon.
"It's pitiful to lose like this, it's not a good image to give and there's not much more to say. We weren't good today, to say the least," Oblak told Movistar Plus.
"Sometimes games like this happen, but we can't afford it because we gave a woeful impression today. I don't have a single positive thing I can say today.
"We didn't show up and there's not much more to say. Nobody is saved from what happened today, we have to accept it and move forward."
Simone accepted Atletico "played badly", but did feel it was not all doom and gloom.
"I always like to think positively and I think it's a good opportunity to keep improving," Simeone told Movistar Plus.
"We had been doing a very good job, today we didn't play the game we expected, but we have to keep going.
"We played badly. We have to accept that. We didn't play well, the substitutions didn't give us the spark that they gave us at other times. We played badly, they were better and we have to accept that.
"There was no lack of tension, attitude or desire to run, we just played badly and when you play badly you are exposed to losses like this.
"We had been doing a very good job and today the game that you don't want to see appeared.
"Some nights are not good and we have to accept them and try to learn from what we had to go through today and recover energy for Sunday's LaLiga game [at Real Sociedad]."
Columbus Crew 2-3 Inter Miami: Messi, Suarez seal Supporters' Shield success
Lionel Messi scored twice and Luis Suarez got the winner as Inter Miami beat 10-man Columbus Crew 3-2 to claim the Supporters' Shield in MLS.
After three straight draws, Miami needed a victory to guarantee they got their hands on the shield, which is awarded to MLS' best team in the regular season, and they got over the line in frantic fashion on Wednesday.
Miami's goals came between the 45th and 48th minute, with Messi, who had not recorded a direct goal contribution in any of his last three away appearances, netting the opening two.
Having already teed up a Diego Gomez goal that was disallowed, Messi engineered space in the box to drill home and break the deadlock, before doubling his tally five minutes later with a sensational free-kick.
Diego Rossi dragged the Crew back into it straight after the restart, but parity lasted just two minutes as Suarez capitalised on an error from Columbus goalkeeper Patrick Schulte.
Cucho Hernandez, who had a goal ruled out for offside in the first half, converted a penalty to reduce the arrears yet again, only for the Crew to go down to 10 when Rudy Camacho picked up two bookings in the space of four minutes.
There was to be more drama, though, as Miami defender Ian Fray was judged to have handled in the area, yet this time, Drake Callender guessed correctly to deny Hernandez and ensure victory for Miami.
Data Debrief: Record points total within reach
That is Miami's second piece of silverware in the bag, after their Leagues Cup triumph last year, and the Herons' focus will now switch to an MLS record.
If they win their remaining two games before the postseason, against Toronto FC and New England Revolution, Miami will set the MLS regular-season points record, overtaking the tally of 73 set by the Revolution in 2021.
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