Jose Mourinho fears Harry Kane could be out for "a few weeks" after the Tottenham captain injured both ankles in a 3-1 Premier League defeat to Liverpool on Thursday.
England striker Kane did not return for the second half at Tottenham Hotspur Stadium after requiring treatment twice in the opening 45 minutes.
Kane has been struck with ankle problems in the past and although Mourinho was unsure over the extent of the damage his talisman sustained, the Spurs boss is braced for having to cope without him in the short term at least.
Asked about Kane's injuries, the Portuguese told Match of the Day: "Two ankles, the first was a bad tackle, it was Thiago [Alcantara]. The second one I didn't know well.
"But two injuries in both ankles, the second one worst than the first one – a few weeks [out], I don't know.
"There are some players you can't replace. When it happens it happens but I believe we have to fight against it, we cannot do anything else."
Spurs face Brighton and Hove Albion on Sunday before taking on Chelsea in a London derby, then face clashes with Everton and Manchester City before coming up against Wolfsberger over two legs in the Europa League next month.
Their eight-match unbeaten run in all competitions was brought to a juddering halt by champions Liverpool, who rediscovered their goalscoring touch with strikes from Roberto Firmino, Trent Alexander-Arnold and Sadio Mane.
Pierre-Emile Hojbjerg had made it 2-1 with a stunning first goal for Spurs after Alexander-Arnold capitalised on a mistake from Hugo Lloris early in the second half.
Son Heung-min had an early goal disallowed for offside after Mane missed a glorious early chance to open the scoring and Mourinho felt Tottenham only had themselves to blame for a defeat that leaves them eight points behind leaders City in sixth place.
"My analysis is that we started very well, but before we scored the offside goal we showed immediately what the game was going to be for us – a big occasion for Mane, a big defensive mistake," he said.
"That was the game for us, the team in the first half was very well organised, the goal is another mistake in the same position.
"The second half we had to make changes, we lose Harry, had to change the structure of the team. First minute, same mistake, second goal. Good reaction, another mistake and goal.
"It was a team fighting against its own mistakes. Some individual mistakes that you saw, you can replay and I cannot say much more than that."
Nashville SC v San Jose Earthquakes: ‘A win would change everything’ - Godoy
Anibal Godoy insists that Nashville are already looking at their game against San Jose Earthquakes on Saturday as a must-win.
Nashville have won just once in the MLS this season and sit in 14th place in the Eastern Conference after a run of four without a win.
The Earthquakes, meanwhile, are bottom of the Western Conference having lost eight of their matches and recording just one win.
Godoy is aware of how their poor start to the season could affect their playoff hopes later down the line but is confident that Nashville can turn things around.
He said: “For us, it's an important week. It's a day we have to win, or we'll start to feel the pressure from other teams as they start to separate in the table.
“This league is long but if we want to get to the playoff you have to win games early on, especially at home.”
Liverpool agree compensation deal for Slot
Liverpool and Feyenoord have reached an agreement in principle over a compensation deal for Arne Slot to become the Reds’ manager next season, according to widespread Dutch media reports.
The Dutchman is reportedly poised to take over from Jurgen Klopp, who announced in January that he would be leaving the club at the end of the campaign.
Slot led Feyenoord to their second Eredivisie title last season after taking over the club in 2021.
It is believed that he topped the list of Liverpool’s favoured candidates due to his attacking playing style and ability to develop players.
Former Liverpool midfielder, Xabi Alonso, who led Bayer Leverkusen to their first Bundesliga title, and Sporting CP’s Ruben Amorim were also reported contenders to take over from Klopp.
Slot had already confirmed his interest in managing in the Premier League, both earlier this week and previously when he was linked to Tottenham in 2023.
QPR 4-0 Leeds United: Shock loss for Farke's men seals Leicester's promotion
QPR thrashed Leeds United 4-0 in the Championship on Friday, ensuring Leicester City booked their promotion straight back to the Premier League.
Ilias Chair was the star for the Hoops as he scored the opener and assisted two more goals to ensure QPR will stay in the Championship for another season.
Lucas Andersen, Lyndon Dykes and Sam Field also got their names on the scoresheet in an emphatic win for Marti Cifuentes' side.
Leeds' heaviest defeat of the season was a huge blow in the race for an automatic promotion spot, with Ipswich Town just one point behind them in third place with two games in hand going into their away clash against Hull City on Saturday.
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