Frank Lampard urged Chelsea's players to show "personal pride" and finish the season strongly as the club target Mauricio Pochettino to become their new head coach.
Injuries are set to keep Reece James and Mason Mount out of action for the rest of the season, Lampard revealed on Tuesday.
The loss of the England internationals comes as the latest blow in a wretched season for the club that has seen two head coaches, Thomas Tuchel and Graham Potter, lose their jobs.
Interim boss Lampard could also be replaced before the campaign ends, having overseen four defeats in four games since the club legend was asked to lead the team.
With Pochettino a firm contender to take charge, there may be a new man at the helm in the coming days or weeks.
What seems nigh-on certain is that Lampard will lead Chelsea in Wednesday's home game against fellow west London outfit Brentford.
The Bees are remarkably five points ahead of the wealthy Blues ahead of that fixture, and Lampard wants to see battling spirit from his 11th-placed side.
He broke the dismal news of the fresh injury setbacks at the beginning of Tuesday's pre-match press conference, saying: "Reece James is unavailable probably for the season, Mason Mount the same – potential for the last game of the season but probably not – so that's obviously disappointing for us.
"They're big players. Reece has a hamstring injury and Mason has been carrying this pelvic injury for quite a while. He's been trying typically, and medical staff have been trying, but we've got to the stage now where he will have minor surgery and then a four-week recovery."
Asked about the potential arrival of former Tottenham and Paris Saint-Germain boss Pochettino, Lampard said: "I'm not going to get involved in any future manager talk, because it's all speculation."
Lampard is unsure whether his short-term position will soon be affected by the club's efforts to appoint a coach, or whether he will continue to lead the team until the end of the season.
"I wouldn't expect anything in football, but I think it's very clear we've come into this club when it's in big difficulties," Lampard said.
He vowed he and his coaching staff would continue to try to draw the best from the expensively assembled Chelsea squad and called on the players to raise their games.
Two Champions League losses to Real Madrid and Premier League defeats to Wolves and Brighton have made it a disappointing start for Lampard.
"I have a big link to this club and pride, and so should the players," Lampard said, when asked whether Chelsea's season was effectively over.
"If you want to take it down your route, it's over, but on my route it's absolutely not over.
"I don't have a mentality that there's nothing to play for. I was fortunate to be a part of teams that were challenging normally for stuff towards the end of the season, but that's not a given. It's important that if you have a long career you won't compete absolutely every season, it's not a given.
"It comes down to your personal pride, responsibility, wearing the shirt. We've got seven games, four against the top four, three away from home.
"The run-in's really tough, there's no doubt about that. There's always something on those games. I understand that and the players have to understand that."
Bristol City Women 0-4 Man City Women: Hosts relegated as Fowler double inspires WSL leaders
Mary Fowler scored twice to set WSL leaders Manchester City on their way to a 4-0 rout of Bristol City, who suffered relegation as a result, on Sunday.
With Arsenal having drawn with Everton earlier in the day, Man City knew a victory would be enough to take the title race down to two teams.
That victory duly arrived in emphatic fashion, with all four of Man City's goals arriving in the second half.
Fowler's fantastic strike opened the scoring in the 62nd minute, with the Australia international doubling her tally soon after, paving the way for an Amy Rodgers own goal and Alex Greenwood's late header to seal a huge victory.
Arsenal are now out of the title race, with Chelsea - who have two games in hand on Gareth Taylor's team - the only side capable of catching Man City.
The Robins, meanwhile, will be playing in the second tier again next term.
Data Debrief: Bristol heading down with a whimper
Bristol City have failed to score in their last five games in the WSL, a run of 544 minutes without a goal.
They mustered just 0.09 expected goals (xG) to Man City's 3.4, with the visitors having now kept a clean sheet in nine of their 20 league games this season.
De Rossi demands more from 'tired' Roma ahead of crunch run
Daniele De Rossi acknowledged his Roma team may be tired, but he insisted they must not allow themselves to be embarrassed.
Roma fought back to draw 2-2 with last season's Serie A champions Napoli in a pulsating fixture on Sunday.
Tammy Abraham's late header secured a point for De Rossi's team, who took the lead through Paulo Dybala's penalty before going behind to goals from Matias Olivera and Victor Osimhen.
With Serie A set to have five teams in the Champions League next season, Roma occupy fifth spot with four matches remaining, but sixth-placed Atalanta are just two points behind with a game in hand.
There is also the small matter of a Europa League semi-final against Bundesliga champions Bayer Leverkusen on the cards over the coming weeks, and De Rossi set the stall out.
"We drew, it is not a result to throw away, but it is not the result or the performance that we wanted," Roma coach Daniele De Rossi told Sky Sports Italia.
"At times you can steal the ball off Napoli, but we then gave it back again too many times. Napoli had a lot of chances in the first half, we did better in the second, but we have to do better.
"Look, we are tired, but we cannot start thinking that we’re tired and that means we can be embarrassed in the final few weeks of the season."
Roma host Leverkusen on Thursday before taking on Juventus on May 5, with a crunch clash against Atalanta – who are also into the Europa League semi-finals – set to follow after the away leg against Xabi Alonso's team.
Key to a successful end to the campaign for Roma will be keeping Dybala fit. The Argentine has been involved in the joint-most goals (12) in Serie A since the turn of the year, scoring nine and setting up three, level with Juve's Dusan Vlahovic.
PSG's latest Ligue 1 title arrives as Monaco lose to Lyon
Paris Saint-Germain have been crowned as Ligue 1 champions after Lyon overcame Monaco 3-2 on Sunday.
A 4-1 midweek win over Lorient ensured that one more victory would be enough for Luis Enrique's team to get over the line, but PSG failed to get the job done themselves when they faced relegation-threatened Le Havre on Saturday.
That game was the 700th match of the QSI era at PSG, and the club's 1,900th in France's top flight.
However, PSG's wait to win their third straight title did not last long, as less than 24 hours later, Lyon – who will face the Parisians in the final of the Coupe de France at the end of May – came out on top in a topsy turvy encounter with second-placed Monaco.
Substitute Malick Fofana was the matchwinner for Lyon, and ultimately the player who handed the title to PSG.
Wissam Ben Yedder had put Monaco ahead in the opening minute, but quickfire goals from Alexandre Lacazette and Said Benrahma turned the match on its head before half-time.
Ben Yedder netted his second to restore parity on the hour mark, and thought he had sealed his hat-trick when he volleyed in from a free-kick, only to have strayed offside.
With only a win good enough for Monaco to stay in the fight, the visitors were then caught out in the 84th minute, with Fofana racing onto Lacazette's throughball and finishing calmly.
After a dismal start to the season, relegation looked a real possibility for Lyon, but they are now, with three games remaining, still in with a shout of qualifying for Europe.
PSG on the other hand now have 12 Ligue 1 titles to their name, with 10 of those coming under QSI's ownership. Aside from the COVID-impacted 2019-20 season, five of their last six league titles have been secured before the start of May.
It also means Luis Enrique remains in the running for a treble in his first season at the club, with PSG taking on Borussia Dortmund in the Champions League semi-finals next week.
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