Manchester City put pressure on Premier League leaders Arsenal ahead of their trip to Liverpool on Sunday with an emphatic 4-1 victory at Southampton.
Erling Haaland's double took him to 30 Premier League goals in 27 games, just 70 shy of Son Heung-min's career total in his eighth season in England after the South Korea international made history on Saturday.
The race for the other top-four places behind Arsenal and City saw Manchester United and Newcastle United both win, while Tottenham remain three points back after riding their luck against Brighton and Hove Albion.
Stats Perform looks at some of the more notable Opta numbers to come out of the pick of Saturday's Premier League action.
Manchester United 2-0 Everton: Wasteful Red Devils still win comfortably
After goals from Scott McTominay and Anthony Martial either side of half-time, United have won 39 Premier League games against Everton, the joint-most one side have against another in the competition's history (also 39 wins for United against Spurs).
Erik ten Hag's men have won 23 of their 28 home games in all competitions this season (D3 L2), their highest total of wins in a single campaign at Old Trafford since 2010-11 (26).
As they continue to fight relegation, Everton have won just one of their last 17 away Premier League games (D7 L9) and remain winless on the road since a 2-1 victory at Southampton in October (11 games since).
McTominay's strike was his fifth in five games for club and country, as many as in his previous 106 appearances for United and Scotland combined.
Ten Hag bemoaned his side's wastefulness as United failed to convert seven big chances – six of which came in the first half – their joint-highest total on record (since 2010-11) in a league match (also seven vs Sunderland in December 2012).
Brentford 1-2 Newcastle United: Bees stung by Magpies
Brentford started well in this one but ultimately failed to win a Premier League game in which they had opened the scoring for the first time (P26 W19 D6 L1), while Newcastle have lost just one of their last five away league games in which they have conceded first (W2 D2), winning the last two.
Eddie Howe has won exactly 100 Premier League points as Newcastle boss (P56 W28 D16 L12), with only fan favourite Kevin Keegan needing fewer games (51) to reach that milestone.
Ivan Toney became just the fourth player to score home and away against Newcastle in a Premier League campaign having previously played for them in the competition, following Louis Saha (2001-02), Craig Bellamy (2008-09) and Abdoulaye Faye (2008-09).
Before netting from the spot, though, Toney failed to score a penalty for the first time since October 2018 for Peterborough United against Barnsley when he saw his first effort saved by Nick Pope, having scored 24 successive penalties before Saturday (excluding shoot-outs).
A David Raya own goal drew Newcastle level, then Alexander Isak scored his eighth Premier League goal to take the points. Seven of those have either drawn Newcastle level (two) or given them the lead (five).
Tottenham 2-1 Brighton and Hove Albion: Son reaches landmark while Seagulls are left to fume
Brighton suffered their first defeat in eight Premier League games on the road (W4 D3) since a 3-1 defeat to Manchester City in October, although they will be tempted to lay a lot of the blame at the door of the officials.
Seagulls boss Roberto Di Zerbi was furious with two goals being ruled out for alleged handballs, while Kaoru Mitoma was also denied what looked like a very good shout for a penalty. The Italian then became the first manager to be sent off twice in the Premier League this season. Cristian Stellini was also dismissed.
For Son, though, it was a landmark day as his terrific opener made him the first Asian player to score 100 Premier League goals, while he is just the 10th player in the league's history to score 100 goals and register 50 assists for one team – and the first to do so for Spurs.
Lewis Dunk equalised in his 200th Premier League appearance, with each of the last four players to mark that milestone in such a way now having been centre-backs (also Kurt Zouma, Virgil van Dijk and Ben Mee).
But after the controversy at the other end, Harry Kane won it for Tottenham with his 10th goal in 12 appearances for the club against Brighton in all competitions. The Seagulls are the ninth team he has reached double-figures against in his career, along with Leicester City, Everton, Arsenal, Southampton, West Ham, Burnley, Crystal Palace and Stoke City.
Southampton 1-4 Manchester City
Kevin De Bruyne was back to his sensational best at St Mary's, registering his 100th Premier League assist, making him the fifth player to reach that mark and doing so in fewer appearances (237) than any of the previous four.
Haaland's brace, including an outrageous bicycle kick, meant he has scored 44 goals in all competitions for City this season – the joint-most ever by a Premier League player in a single campaign, level with Ruud van Nistelrooy (2002-03) and Mohamed Salah (2017-18).
De Bruyne laid on the opener and has assisted seven Premier League goals for Haaland this season, the most one City player has ever assisted for another in a single campaign.
Jack Grealish teed up the other Haaland goal and also got on the scoresheet. He has now been involved in 10 goals in 15 league games since the World Cup (four goals, six assists). Only Haaland (14) has been involved in more for Pep Guardiola's team in that time, while it is three more than Grealish managed in his first 34 appearances for City (four goals, three assists).
Julian Alvarez replaced Haaland and dispatched a second-half penalty, becoming the fifth different City player to score as a substitute in the Premier League this season, with only United and Wolves (six) having more.
Sessegnon rejoins boyhood club Fulham after Tottenham departure
Ryan Sessegnon has resigned for Fulham on a free transfer, five years after leaving the club.
The 24-year-old signed a two-year contract with the Cottagers with the option to extend for a further year following his departure from Tottenham last month.
In his first spell at the club, Sessegnon worked his way through the academy over 11 years, scoring 25 goals in 120 first-team appearances.
He then moved to Spurs in a £25million deal in 2019, though struggled to nail down a place in North London, making just 57 appearances in all competitions, and scoring three goals.
"It's amazing to be back. Emotional, as well," he told FFCtv. "It's where it started for me, where everything began, and it's amazing to be back.
"It will always be home for me. I think it had the feeling that it was meant to be, coming back here, so I'm delighted to get it done."
Sessegnon is Fulham's first signing of the transfer window, though they have seen plenty of first-team departures already, with Joao Palhinha, Tosin Adarabioyo and Bobby De Cordova-Reid all leaving the club.
Dewsbury-Hall: Maresca will surprise people at Chelsea
Kiernan Dewsbury-Hall believes new Chelsea manager Enzo Maresca will "surprise a lot of people" when they watch the Blues this season.
The Italian led Leicester City straight back to the Premier League as Championship winners in his only season in charge and succeeds Mauricio Pochettino at Stamford Bridge.
The Foxes topped the second division table with 98 points, with Dewsbury-Hall a key figure in his squad as he netted 12 goals and provided 14 assists last season – his best tally in a single campaign.
Dewsbury-Hall was also named Leicester's Player and Players' Player of the Year.
The midfielder made the switch to West London earlier this month for £30million and is confident that Maresca will have Chelsea challenging for trophies in no time.
"The manager was a big catalyst in wanting me to come," Dewsbury-Hall told BBC Sport.
"I knew from Leicester, a club that went down and had a lot of problems, how he managed to galvanise that if everyone manages to buy into the system.
"I genuinely think in a short space of time we can be pushing for minimum top four - but more than that.
"He may be unknown for a lot of people, but he is top, top level. He will surprise a lot of people."
Chelsea's pre-season got off to a frustrating start as they were held to a 2-2 draw by League One side Wrexham in Maresca's first game in charge on Wednesday.
Dewsbury-Hall did not play in that match but is training with the squad in the United States and could feature in their next outing against Celtic on Saturday.
The 25-year-old is confident the manager's tactics will come across soon, with the players buying into his style.
"We've only been doing it for two or three weeks, but the combination plays are really quick and tidy," he added.
"That's after two weeks. I remember he said to us at Leicester after six months or a year, there might be teething problems at the start, but it will improve.
"Within the first week at Leicester, I was convinced this was top, top level. I felt a bit stupid; I thought I knew a lot about football, but he was teaching me things on a daily basis that I didn't really know before. He has an aura, he can be strict, or gentle and soft - he has both sides.
"I am getting the same feedback here with the lads. They've bought into it here from minute one which is exciting. With a system and philosophy, you need everyone to buy in because, if they do, you can really achieve something."
Ederson slams reports of rift with Man City backup Ortega
Ederson has hit out at reports of a rift between himself and fellow Manchester City goalkeeper Stefan Ortega.
The Brazilian was substituted after suffering a fractured eye socket in City's penultimate game of the Premier League season, a vital 1-0 win over Tottenham.
Ortega replaced him and made a brilliant save to deny Son Heung-min as City maintained their slender lead over Arsenal at the top of the table, sealing an unprecedented fourth straight title by beating West Ham five days later.
Ortega was widely lauded for his role in that triumph, and an article published by The Athletic this week suggested Ederson took issue with that praise.
However, the goalkeeper – who missed the Copa America as a result of his injury – has now moved to shut down those suggestions with a post to his Instagram story.
"I would like to clarify that the note published by The Athletic yesterday, referring to my alleged dissatisfaction with a co-worker, is completely false," he wrote.
"The alleged day reported was, without a doubt, one of the most difficult days of my career, when I suffered a fracture that prevented me from playing in the final stretch of the season and, consequently, from representing my country in the Copa America.
"At the time of the injury, my only thought was to continue in the match, defending City in the fight for the title.
"But the emotion of the match would be greater than the reality and, inevitably, I would not be able to continue as I would have liked due to the damage it caused, completely blocking my field of vision. I remain focused on preparing for the season."
Ederson has been linked with a transfer in recent days, reportedly attracting interest from Saudi Pro League clubs.
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