Though neither has hope of winning the Scudetto this season, history will be made at San Siro when Inter and Juventus meet in one of the Italian football's most famous fixtures.
Eighteen points behind Napoli, second-placed Inter are looking over their shoulders at those behind them in a tight fight for the Champions League places.
Had they not been deducted 15 points, Juve would be above Inter and firmly in that battle.
As it is, victory here is critical for Juve's slim chances of climbing into the top four — they are 10 points adrift of fourth-placed Milan — with both sides hoping the Rossoneri slip up at Udinese and Lazio and Roma play out a draw.
And, as Stats Perform explains in a look at the standout Opta numbers ahead of the Derby d'Italia, history is on the side of Juve keeping themselves in the hunt.
Juve dominance
Inter and Juve are set to face off for the 180th time in the top flight, making it the fixture with the most matches in Serie A history.
Juve have dominated this great rivalry, winning 86 matches compared to 48 for Inter, with 45 games finishing as a draw.
The hosts have long since struggled in this fixture when it has been played in the second half of the season. They are winless against Juve at home in Serie A in such games since April 2010.
On top of that, since winning the treble 13 years ago, Inter have prevailed in just two their 12 total home league games against the Bianconeri (D5 L5).
Key to improving that record may be Lautaro Martinez, who has scored four home goals in Serie A in 2023, a tally only Adrien Rabiot and Victor Osimhen can match.
However, the World Cup winner has only scored one goal in nine top-flight games against Juventus and has a goal average of one every 586 minutes against the Bianconeri: his worst in Serie A against any opponent versus whom he has found the net.
Bianconeri back at their best
From an Inter perspective, Juve head into this game in worryingly good form.
Indeed, the Bianconeri are playing at a level not far away from that of runaway leaders Napoli.
Only Napoli (23) have scored more goals than Juventus (20) in Serie A in 2023, while Partenopei are the sole team to have claimed more wins (9) than Massimiliano Allegri's side in this calendar year.
Perhaps of even more concern for Inter is the contrast in form between the two sides in the match immediately after a European contest.
Another Champions League hangover?
Inter got the job done in Porto in midweek and, through to a quarter-final with another Portuguese opponent in Benfica, can have hope of a first Champions League final appearance since their triumph in 2010.
But the Nerazzurri have struggled of late in games following Champions League tussles. Inter have lost three of their last six Serie A matches after their Champions League games, including their last two (against Bologna and Juventus in the reverse match).
Juve are competing in the Europa League after failing to make it out of the Champions League group stage, but they have won each of their last such six league games after Continental encounters.
If Juve repeat the feat from the reverse fixture and defeat Inter without conceding, it will mark the first time they have won both games in this fixture to nil since the 1976-77 season.
Bristol City Women 0-4 Man City Women: Hosts relegated as Fowler double inspires WSL leaders
Mary Fowler scored twice to set WSL leaders Manchester City on their way to a 4-0 rout of Bristol City, who suffered relegation as a result, on Sunday.
With Arsenal having drawn with Everton earlier in the day, Man City knew a victory would be enough to take the title race down to two teams.
That victory duly arrived in emphatic fashion, with all four of Man City's goals arriving in the second half.
Fowler's fantastic strike opened the scoring in the 62nd minute, with the Australia international doubling her tally soon after, paving the way for an Amy Rodgers own goal and Alex Greenwood's late header to seal a huge victory.
Arsenal are now out of the title race, with Chelsea - who have two games in hand on Gareth Taylor's team - the only side capable of catching Man City.
The Robins, meanwhile, will be playing in the second tier again next term.
Data Debrief: Bristol heading down with a whimper
Bristol City have failed to score in their last five games in the WSL, a run of 544 minutes without a goal.
They mustered just 0.09 expected goals (xG) to Man City's 3.4, with the visitors having now kept a clean sheet in nine of their 20 league games this season.
De Rossi demands more from 'tired' Roma ahead of crunch run
Daniele De Rossi acknowledged his Roma team may be tired, but he insisted they must not allow themselves to be embarrassed.
Roma fought back to draw 2-2 with last season's Serie A champions Napoli in a pulsating fixture on Sunday.
Tammy Abraham's late header secured a point for De Rossi's team, who took the lead through Paulo Dybala's penalty before going behind to goals from Matias Olivera and Victor Osimhen.
With Serie A set to have five teams in the Champions League next season, Roma occupy fifth spot with four matches remaining, but sixth-placed Atalanta are just two points behind with a game in hand.
There is also the small matter of a Europa League semi-final against Bundesliga champions Bayer Leverkusen on the cards over the coming weeks, and De Rossi set the stall out.
"We drew, it is not a result to throw away, but it is not the result or the performance that we wanted," Roma coach Daniele De Rossi told Sky Sports Italia.
"At times you can steal the ball off Napoli, but we then gave it back again too many times. Napoli had a lot of chances in the first half, we did better in the second, but we have to do better.
"Look, we are tired, but we cannot start thinking that we’re tired and that means we can be embarrassed in the final few weeks of the season."
Roma host Leverkusen on Thursday before taking on Juventus on May 5, with a crunch clash against Atalanta – who are also into the Europa League semi-finals – set to follow after the away leg against Xabi Alonso's team.
Key to a successful end to the campaign for Roma will be keeping Dybala fit. The Argentine has been involved in the joint-most goals (12) in Serie A since the turn of the year, scoring nine and setting up three, level with Juve's Dusan Vlahovic.
PSG's latest Ligue 1 title arrives as Monaco lose to Lyon
Paris Saint-Germain have been crowned as Ligue 1 champions after Lyon overcame Monaco 3-2 on Sunday.
A 4-1 midweek win over Lorient ensured that one more victory would be enough for Luis Enrique's team to get over the line, but PSG failed to get the job done themselves when they faced relegation-threatened Le Havre on Saturday.
That game was the 700th match of the QSI era at PSG, and the club's 1,900th in France's top flight.
However, PSG's wait to win their third straight title did not last long, as less than 24 hours later, Lyon – who will face the Parisians in the final of the Coupe de France at the end of May – came out on top in a topsy turvy encounter with second-placed Monaco.
Substitute Malick Fofana was the matchwinner for Lyon, and ultimately the player who handed the title to PSG.
Wissam Ben Yedder had put Monaco ahead in the opening minute, but quickfire goals from Alexandre Lacazette and Said Benrahma turned the match on its head before half-time.
Ben Yedder netted his second to restore parity on the hour mark, and thought he had sealed his hat-trick when he volleyed in from a free-kick, only to have strayed offside.
With only a win good enough for Monaco to stay in the fight, the visitors were then caught out in the 84th minute, with Fofana racing onto Lacazette's throughball and finishing calmly.
After a dismal start to the season, relegation looked a real possibility for Lyon, but they are now, with three games remaining, still in with a shout of qualifying for Europe.
PSG on the other hand now have 12 Ligue 1 titles to their name, with 10 of those coming under QSI's ownership. Aside from the COVID-impacted 2019-20 season, five of their last six league titles have been secured before the start of May.
It also means Luis Enrique remains in the running for a treble in his first season at the club, with PSG taking on Borussia Dortmund in the Champions League semi-finals next week.
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