Leandro Trossard and Casemiro were two of the standout players in Sunday's Premier League action – though for contrasting reasons.
Belgium international Trossard was inspirational as Arsenal's title tilt remained on track, while Casemiro was shown a second red card in three Premier League appearances as Manchester United slipped up again.
Miguel Almiron was Newcastle United's hero, Eddie Howe's men closing on the Champions League places again, and Ollie Watkins continued his fine form for Aston Villa in their draw with West Ham.
After the conclusion of the day's drama, Stats Perform highlights the pick of the Opta numbers.
Manchester United 0-0 Southampton: Another Casemiro red threatens to derail Ten Hag's men
Casemiro has undoubtedly been one of United's best players this season, but if they now miss out on the top four, the Brazil international will have to take part of the blame.
His sending off in the first half on Sunday for a heavy challenge on Carlos Alcaraz proved costly, with United only able to scrape a point thereafter.
That made him the first United player to receive two red cards in one Premier League season since Nemanja Vidic in 2013-14, and just the second to earn a pair of reds in his first campaign for the club after Darren Fletcher (2003-04).
He will now miss their next four matches – at the end of that run, he will have been suspended for eight games this year alone.
While some United fans might have had the perception this was always going to be the risk that came with signing a player like Casemiro, he had never been shown a straight red in his entire senior career before moving to Old Trafford.
Of course, for Southampton, Casemiro's dismissal proved helpful. While they could not get the win they might feel they deserved, Saints managed to keep a third clean sheet in four games under Ruben Selles – that is one more than in their previous 34 league games.
Fulham 0-3 Arsenal: Trossard inspirational as Gunners continue to deal out capital punishment
Arsenal's comprehensive win at Craven Cottage was their fifth successive away London derby win without conceding a goal.
That is a feat no club has managed previously in the Premier League.
Trossard played a vital role with a unique feat of his own, setting up all three of Arsenal's goals, with each one coming in the first half.
Thus, the Belgian became the first player to ever tally a hat-trick of assists in the first half of a Premier League away game.
Trossard's second was a looping cross that found Gabriel Martinelli for a close-range header, the Brazilian nodding in his 23rd top-flight goal for the club.
He is now only one away from surpassing Nicolas Anelka as the foreign player with the most Premier League strikes for the club before turning 22.
That first-half flurry keeps the Gunners on track in the title race, five points clear of Manchester City in second.
West Ham 1-1 Aston Villa: Watkins in a groove
Unai Emery has certainly managed to steady the ship at Aston Villa since replacing Steven Gerrard in the dugout, and the form of Watkins has been among the most notable improvements.
The striker netted again on Sunday, opening the scoring at London Stadium as he headed in from Alex Moreno's cross.
Since the World Cup, only Marcus Rashford (10), Erling Haaland (10) and Harry Kane (eight) have scored more Premier League goals than Watkins (seven).
That includes goals in each of his past four Premier League away games, which is the longest such scoring run by a Villa player since Dwight Yorke between March and May 1998 (also four).
Unfortunately for Villa, West Ham levelled just nine minutes later through Said Benrahma, who was lively throughout.
His penalty continued his 100 per cent record from the spot in English league football, with that his third from three for West Ham having also converted 4/4 at Brentford.
Over the course of the 90 minutes, Benrahma had 10 shots, which is the joint-most on record (since the 2003-04 season) for a West Ham player in a single Premier League game.
He could not single-handedly inspire a turnaround, however.
Newcastle United 2-1 Wolves: Almiron comes up trumps yet again
Almiron has stepped up this season, becoming a key player for Newcastle and a regular source of goals.
A recent dip in form saw him dropped from the starting XI for the visit of Wolves on Sunday, but he responded well.
Eleven minutes after his second-half introduction, he found space in the right side of the box and saw a deflected effort beat Jose Sa following Joe Willock's well-timed pass.
That was his fourth winning goal of the season – the most among Newcastle players – and his 11th goal in total in the Premier League, which is four than his previous four campaigns combined.
Earlier, Hwang Hee-chan had equalised just 57 seconds after coming off the bench, making it the second-fastest substitute goal of the season.
But the day belonged to Almiron as Newcastle ended a five-match winless streak.
Guardiola insists three teams still in title hunt despite Liverpool slip-up
Pep Guardiola insists Liverpool remain in the Premier League title race, despite the Reds losing further ground on Arsenal and Manchester City in a dramatic few days at the summit.
Liverpool suffered a surprise 2-0 defeat to Merseyside rivals Everton on Wednesday, a result which meant they failed to close the gap to Arsenal after the Gunners thrashed Chelsea 5-0 on Tuesday.
While Jurgen Klopp's men couldn't respond to the Gunners pulling clear, City did on Thursday, with Phil Foden scoring twice in an emphatic 4-0 win over Brighton at the Amex Stadium.
One point behind Arsenal with a game in hand, City know five wins from their five remaining matches will seal an unprecedented fourth successive English top-flight title.
However, Guardiola expects further twists and turns in the coming weeks.
Asked if Liverpool were still in contention after City's win, Guardiola told Sky Sports: "Yeah. Many things can happen.
"What happened with Liverpool, losing to Crystal Palace and Everton, can happen to us. It can happen to Arsenal. No-one is safe. We have to rest. Now it is just about recovering for the next one.
"We have been here in the past but being here in the past doesn't mean it is going to happen. We have to do the things to make it happen."
City's comprehensive win – in which Kevin De Bruyne scored his first headed goal in the Premier League – saw them cut Arsenal's goal difference advantage to eight goals.
However, Guardiola believes it will be tough for City to close that gap, saying: "It is difficult to cut. The margin is so big. They score a lot of goals and don't concede.
"The main thing is to win the games. We have five games left and they are tough ones – it's a lot of games. We'll take it one game at a time."
Foden's first goal against Brighton – a deflected free-kick – saw him become just the third player to score 50 top-flight goals under Guardiola while aged 23 or younger, after Erling Haaland and Lionel Messi.
Foden is the favourite to be named Premier League Player of the Season, and while Guardiola believes he should be in contention, he says his player is more concerned with team honours.
"For sure, but he wants to win the Premier League," Guardiola said when asked if Foden deserved individual honours. "His influence in the final third was better than in the last two or three games. Today he was more calm, his decision-making was good and to score goals is always good."
Foden: De Bruyne the best in the Premier League
Phil Foden hailed Manchester City team-mate Kevin De Bruyne as the Premier League's best player after the pair both netted in the 4-0 win over Brighton and Hove Albion.
De Bruyne opened the scoring in Thursday's contest at Amex Stadium before Foden took over with a couple of goals of his own before half-time.
Julian Alvarez rounded off the scoring just after the hour in a one-sided contest as an Erling Haaland-less City moved to within a point of leaders Arsenal with a game in hand.
Belgium international De Bruyne now has four goals and six assists in just 13 league appearances for City this season.
Speaking to Sky Sports News after the win over Brighton, Foden said: "I think when he is at it, he is the best player in the Premier League."
Foden's first goal came via a deflected free-kick that he himself won, although replays showed he slipped rather than being fouled.
The England international doubled his personal tally with a composed finish after Brighton were caught in possession at the back.
Asked about playing more centrally, Foden said: "I have always said that I see myself there. This year I have moved inside and it has helped me massively.
"I enjoy it in the middle. It's where I want to be. At the moment, I am just enjoying my football and playing with freedom."
De Bruyne had earlier opened the scoring with a brilliant opener - his first headed goal for City in the Premier League - as City made it 30 games unbeaten in normal time across all competitions.
Alvarez then went on to round off the scoring in a game that not only saw the reigning champions close the gap on Arsenal, but also narrow the goal difference margin to eight.
"It was a good game," De Bruyne said. "I think we played really good in the first half and every game is a lot of pressure. All we can do is prepare as we did today and win the game that is in front of us.
"We just want to win game-by-game and push for the title. We don't get ahead of ourselves. Now the next game is coming quickly. Try to recover and we go again."
Kyle Walker assisted the De Bruyne and Alvarez goals - the first time the defender has set up two goals in a single Premier League game in what was his 390th appearance in the competition.
Reflecting on his rare headed goal, De Bruyne said: "It doesn't happen too much. Kyle gave a good cross and I think the only way I could reach it is by jumping to it. I will take it but it's not something I am good at."
City have rather ominously won four Premier League games in a row and travel to strugglers Nottingham Forest next up at the weekend, knowing victory in their remaining five games will secure an unprecedented fourth straight title.
"I trust my team. All respect to Liverpool and Arsenal, they are amazing," De Bruyne added. "Arsenal are doing what they need to do and we are also needing to do it. Work hard and be humble enough to keep pushing."
Brighton 0-4 Manchester City: Foden at the double as champions leapfrog Liverpool
Phil Foden scored twice as Manchester City leapfrogged Liverpool and kept the Premier League title race in their own hands by thrashing Brighton 4-0.
Foden moved onto 16 league goals for the season with a first-half brace at the Amex Stadium, seeing a free-kick deflect past a wrongfooted Jason Steele before stroking home after some reckless play from the Seagulls.
De Bruyne had earlier given City the lead with what was his 68th Premier League goal but the first with his head, as Pep Guardiola's men made light of Erling Haaland's injury-enforced absence.
Julian Alvarez added a fourth as City pulled two points clear of Liverpool and within one of Arsenal with a game in hand, knowing five further wins will guarantee they retain their crown.
Brighton, meanwhile, stay in the bottom half with 44 points, having been surpassed by Bournemouth on Wednesday.
Nathan Ake could not keep his shot down when presented with the first half-chance after a low-key start, but City went ahead with a brilliant goal after 17 minutes.
Foden slipped Kyle Walker in on the right flank, and De Bruyne watched the full-back's cross all the way before sending a wonderful diving header into the top-right corner.
There was more fortune about City's second, which arrived just nine minutes later as Foden's free-kick deflected in off Pascal Gross amid Brighton complaints about how Foden won the set-piece.
Brighton only had themselves to blame when Foden got his second after 34 minutes, though. Valentin Barco conceded possession cheaply on the edge of his area, and Foden swept the loose ball into the bottom-left corner.
Ederson denied Joao Pedro as Brighton improved in the second half, but City had further daylight just after the hour mark, Walker breaking in behind and beating Steele to a loose ball, with Alvarez on hand to turn home.
Brighton were enraged when Josko Gvardiol avoided conceding a penalty for a clumsy challenge on Pedro, who skewed wide late on as City – who went close to a fifth through Jeremy Doku late on and face struggling Nottingham Forest next – claimed a statement win.
Foden's star still rising
Foden has emerged as the favourite to be crowned Premier League Player of the Season, and he has gone up a gear in the run-in, also scoring a hat-trick on his last league appearance when City thrashed Aston Villa 4-1 earlier this month.
He was in imperious form again on Thursday, even if Brighton's fans were not happy with the way he went down for the free-kick that ultimately resulted in his first goal.
That strike was Foden's 50th in the Premier League, making him just the third player to score 50 top-flight goals under Guardiola while aged 23 or younger, after Lionel Messi and Erling Haaland.
It is no wonder Brighton's fans are sick of the sight of the England man; he has eight goals in his last eight Premier League appearances against the Seagulls, more than he has scored against any other club in the competition.
Seagulls' wings clipped
Hampered by injuries to the likes of Pervis Estupinan, Kaoru Mitoma and Evan Ferguson, Brighton have seen their European hopes falter in recent weeks and now appear to be limping to the finishing line.
Roberto De Zerbi's team are winless in their last five Premier League games (two draws, three defeats) and sit six points adrift of the top seven with matches against Bournemouth, Aston Villa, Newcastle United, Chelsea and Manchester United to come.
Brighton have even seen their supply of goals dry up, scoring just four times in eight league matches since thrashing Sheffield United 5-0 in February.
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