Pakistan are in discussions with England over postponing the opening Test between the pair following illness in the tourists' camp.
The two are set to meet in their first red-ball match in Pakistan since 2005 this week, beginning a three-match series in Rawalpindi on Thursday.
But an infection has swept through England's party, disrupting their preparations, with only a handful of the squad training on Wednesday.
Now, the Pakistan Cricket Board is in dialogue with the England and Wales Cricket Board over delaying the fixture.
"The PCB and ECB are in discussions regarding the commencement of the first Test as some England players are down with [a] viral infection," said the PCB.
"The PCB continues to monitor the situation, is in contact with the ECB and will provide further updates in due course."
England batsman Joe Root, one of a handful of players who trained on Wednesday, suggested a postponement was the right decision to make, stating the tourists did not wish to shortchange the occasion.
"It's such a monumental tour and important series for so many reasons," he told BBC Sport. "We've waited 17 years to come to Pakistan to play a Test match.
"If it means waiting another day, is that the worst thing in the world? We're all desperate to play this game, and we know how important it is to the fans of Pakistan and their team as well."
Root was succeeded by Ben Stokes as captain earlier this year and ruled out leading the side if the latter was indisposed, suggesting Ollie Pope should instead deputise.
"I don't think that's going to be the case," he added when asked if he would skipper England. "Last week Popey did a great job in the warm-up game. I think that might be a better way for the group moving forward."
Dr. Donovan Bennett defeats Billy Heaven in JCA Presidential election
Dr. Donovan Bennett is the new president of the Jamaica Cricket Association after defeating Wilford ‘Billy’ Heaven at Thursday’s elections at the 20th JCA Annual General Meeting held at the Jamaica Conference Centre in Kingston.
Bennett, who served as JCA vice-president for 11 years, is set for his first term at the helm after a 67-30 victory.
Heaven served as JCA president for the last 10 years and was seeking a fifth term.
New Zealand take unassailable series lead after hard-fought victory over Pakistan
Pakistan slumped to a four-run defeat at the hands of New Zealand despite the efforts of Abbas Afridi and Fakhar Zaman.
The Black Caps took an unassailable 2-1 lead in the five-match T20I series, thanks in the main to Tim Robinson (51) and bowling duo William O'Rourke (3-27) and Ben Sears (2-27) on Thursday.
Set a target of 179 to win, Pakistan looked on their way to victory when Fakhar Zaman got going, but he was eventually dismissed on 61 by Sears.
Abbas took three wickets in New Zealand's innings, yet he could only contribute a single run to Pakistan's cause as the hosts fell just short in Lahore.
Data Debrief
Shadab Khan did not bowl a single delivery for Pakistan, which is the first time that has happened in a completed T20I innings.
He did take an exceptional catch to dismiss Mark Chapman, but it was not enough to inspire Pakistan.
IPL: Kohli and Patidar star to snap RCB's losing streak
Royal Challengers Bengaluru ended a six-match losing streak in the Indian Premier League by claiming a convincing 35-run win over Sunrisers Hyderabad.
Bengaluru still sit bottom of the standings, but have reason to cheer after Virat Kohli's 51 and Rajat Patidar's 20-ball 50 got the job done in style on Thursday.
Cameron Green chipped in with a useful 37 as RCB reached 206-7 from their 20 overs, and the Australian then took 2-12 with the ball as the Sunrisers failed to get going.
Shahbaz Ahmed top scored for Sunrisers with 40 not-out, but it was not enough as they only mustered 171-8 in response.
Data Debrief
Thursday's match marked Jaydev Unadkat's 100th in the IPL, and though he finished on the losing side, he did take a memorable three-for to celebrate the occasion.
It was Unadkat who dismissed Kohli, Patidar and Mahipal Lomror, finishing with figures of 3-30.
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