Rotterdam Open top seed Stefanos Tsitsipas and defending champion Felix Auger-Aliassime were joined by Daniil Medvedev in progressing through their first-round ties.
Auger-Aliassime won his first Tour-level title at the event last year and went from strength to strength in 2022, winning another three singles trophies.
The world number eight, seeded third, started his title defence with a convincing 6-2 6-3 defeat of Italy's Lorenzo Sonego on Tuesday.
"Of course, I was hoping to win and get through, but 6-2, 6-3 is a great performance against a player that is tricky like he is... it's a great way to start the week," said Auger-Aliassime, who needed just 82 minutes to clinch victory and set up a last-16 meeting with qualifier Gregoire Barrere.
The Canadian is relishing his title defence, and feels he is a stronger competitor than this time last year in a warning shot to his rivals.
He added: "Last year was an amazing year, but this year is a different one. I think I'm a better player overall.
"Of course, the best thing I can do compared to last year is win again, so hopefully I can do that. The draw is really strong, but I'm confident if I can keep playing the way I did today I'll get my chances and then we'll see."
Auger-Aliassime might be the reigning champion, but world number three Tsitsipas is the favourite.
Emil Ruusuvuori was no match for Australian Open runner-up, who prevailed 7-5 6-1 and has a 13-1 record for the season.
"The process that you get to repeat these things over and over again, it gives you tremendous understanding of how things actually work," Tsitsipas said.
"I think being able to get in these moments more and more often on the Tour helps you understand, makes you wiser when you're trying to deal with all these problems."
Tsitsipas, who could face Open Sud de France champion Jannik Sinner in the next round, ensured there would be no curse of the top seed in Rotterdam, where the favourite had lost their first match in two of the last three editions.
On both occasions (2020 and 2021), that was Medvedev, but the former world number one fought from a set down to beat Alejandro Davidovich Fokina 4-6 6-2 6-2.
World number 10 Hubert Hurkacz also had to battle against a Spaniard in the form of Roberto Bautista Agut. The fifth seed needed three hours to win 7-5 6-7 (7-9) 7-6 (7-4) and tee up an encounter with Grigor Dimitrov.
Alexander Zverev defeated Soonwoo Kwon in straight sets to book his progress, while Gijs Brouwer got the better of Marc-Andrea Huesler.
Jarry defeats Paul to set up Zverev showdown in Italian Open final
Nicolas Jarry defeated Tommy Paul in three sets on Friday to set up a showdown with Alexander Zverev in the Italian Open final.
The men's world number 24 prevailed 6-3 6-7 (3-7) 6-3 in a little under three hours in Rome to reach his first ATP Masters 1000 final.
Jarry earned the only break of serve in the eighth game of the opening set, but Paul - who dropped just one set in four matches en route to this stage - hit back in the second.
Birthday boy Paul lost serve to trail 4-2 at one stage, but he produced one of the shots of the tournament at the ideal moment and soon dragged it back to 4-4.
A gruelling set concluded with Paul taking the tie-break 7-3, but Jarry was unperturbed and won the deciding set with his fifth match point to see off Paul in a gruelling contest.
Data Debrief:
Jarry is the third male Chilean in the Open Era to reach the singles final of the Italian Open after Marcelo Rios (1997-98) and Fernando Gonzalez (2007).
The 28-year-old registered 13 aces against Paul to his opponent's seven and hit 35 winners to 19 in a deserved victory.
Zverev ends Tabilo's dream run to reach Italian Open final
Alexander Zverev fought back from the brink to reach the Italian Open final on Friday, overcoming Alejandro Tabilo by a 1-6 7-6 (7-4) 6-2 scoreline in the last four.
Zverev was punished for a slow start as Tabilo took the opener within 32 minutes, but the German fought back in a one-hour, 15-minute slog of a second set.
The 2017 Italian Open champion put his foot down from 3-3 in the second-set tie-break, with Tabilo potentially feeling the effects of a fine run that included a last-32 upset of Novak Djokovic.
Zverev upped the intensity in the final set and won a huge 94 per cent of points behind his first serve as his opponent wilted, the third seed reaching the Rome final for a third time.
Data Debrief: Zverev draws level with Becker
Zverev will now face either Nicolas Jarry or Tommy Paul in Sunday's final, which will be his 11th at ATP 1000 Masters level.
That tally pulls him level with Boris Becker for most such finals by a German player since the format's 1990 introduction.
Sabalenka defeats Collins to set up Swiatek rematch
Aryna Sabalenka defeated Danielle Collins 7-5 6-2 to set up yet another meeting with Iga Swiatek at the Italian Open.
Having defeated Collins en route to the final of the Madrid Open, which she lost to Swiatek, Sabalenka repeated the trick with a straight sets win over the American in Thursday's semi-final.
And the Belarusian's reward will be an immediate rematch with Swiatek.
The duo have met 10 times, including in Madrid earlier this month, with Swiatek winning seven times and Sabalenka claiming three victories.
This will be Sabalenka's first appearance in the Italian Open final.
She is the sixth player, along with Simona Halep (2017), Dinara Safina (2009), Serena Williams (2013), Ons Jabeur (2022), and Swiatek (2024) to have reached the final of both Madrid and Rome in the same season.
Data Debrief: Perfect record
Collins is the only player against whom Sabalenka has registered six wins without a loss in WTA events, while only against Maria Sakkari and Elise Mertens does she have more wins in her career in such events (seven each).
The final will mark the fourth meeting on clay between Swiatek and Sabalenka as world number one and two, equalling Chris Evert and Martina Navratilova for the most meetings on the surface as the WTA's top-two ranked players.
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