Dominic Thiem's run at the Winston-Salem Open came to a halt as Jack Draper claimed a comfortable straight sets victory on Wednesday.
In the first meeting between Draper and Thiem, it was the 20-year-old Brit who sealed his place in the last eight with a routine 6-1 6-4 victory.
Draper charged ahead in the first set, creating five chances to break and taking two of them, while his sole successfully converted break point in the second set paved the way for the Winston-Salem debutant to serve out the match.
World number 55 Draper has now reached three Tour-level quarter-finals this season, while 2020 US Open champion Thiem had been on a run of making it to the last eight in his last three tournaments, in Bastad, Gstaad (where he made the semis) and Kitzbuhel.
Draper did not offer up a single break opportunity, and said: "I was really good behind serve, really solid. In the second set it was tough because he was coming up with some amazing shots. It was a real honour to be on court with Dominic. He's an amazing player.
"I started confidently, I started well. I was hitting through the ball, felt good in the conditions. It was a difficult start because I felt like everyone was supporting Dominic and I knew that I needed to come out confidently and sharp, and that's what I did."
Draper will meet Marc-Andrea Huesler in the quarter-finals, after the world number 102 overcame Ilya Ivashka.
Botic van de Zandschulp is the favourite after Grigor Dimitrov's retirement due to illness with the Dutchman progressing to the last eight by defeating Spain's Jaume Munar in straight sets. He will face Benjamin Bonzi after the Frenchman's 7-5 6-2 defeat of Thiago Monteiro.
Maxime Cressy will face Adrian Mannarino after coming from a set down to beat Lorenzo Sonego 6-7 (4-7) 6-2 7-6 (7-3), while Richard Gasquet and Laslo Djere make up the other quarter-final tie after respective victories over Steve Johnson and Jason Kubler.
Swiatek seals Italian Open hat-trick after soaring past Sabalenka
Iga Swiatek stormed to her third Italian Open title following a dominant 6-2 6-3 victory over Aryna Sabalenka.
The world number one took just under an hour-and-a-half to deny the world number two, and complete a hat-trick of triumphs in Rome.
The pair were contesting a second final in as many events, with Swiatek saving three championship points before eventually prevailing in the Madrid Open showpiece a fortnight ago.
However, it was one-way traffic this time around. The Pole converted two out of three break points as she controlled the opening set.
Sabalenka was the last player to deny Swiatek in a WTA final, that coming at last year's Madrid Open.
Although, the second seed was helpless as her opponent broke again in game seven of the second set, before wrapping up a fourth title of the season ahead of the French Open later this month.
Data debrief
Landing her third Italian Open title before turning 23, Swiatek is only the second player to achieve that feat after Gabriela Sabatini.
In fact, at 22 years and 352 days old, she is the youngest player to win 10 WTA 1000 titles since the introduction of the format in 2009.
The Pole also became the third player to triumph in Madrid and Rome during the same season, after Dinara Safina (2009) and Serena Williams (2013).
Jarry defeats Paul to set up Zverev showdown in Italian Open final
Nicolas Jarry defeated Tommy Paul in three sets on Friday to set up a showdown with Alexander Zverev in the Italian Open final.
The men's world number 24 prevailed 6-3 6-7 (3-7) 6-3 in a little under three hours in Rome to reach his first ATP Masters 1000 final.
Jarry earned the only break of serve in the eighth game of the opening set, but Paul - who dropped just one set in four matches en route to this stage - hit back in the second.
Birthday boy Paul lost serve to trail 4-2 at one stage, but he produced one of the shots of the tournament at the ideal moment and soon dragged it back to 4-4.
A gruelling set concluded with Paul taking the tie-break 7-3, but Jarry was unperturbed and won the deciding set with his fifth match point to see off Paul in a gruelling contest.
Data Debrief:
Jarry is the third male Chilean in the Open Era to reach the singles final of the Italian Open after Marcelo Rios (1997-98) and Fernando Gonzalez (2007).
The 28-year-old registered 13 aces against Paul to his opponent's seven and hit 35 winners to 19 in a deserved victory.
Zverev ends Tabilo's dream run to reach Italian Open final
Alexander Zverev fought back from the brink to reach the Italian Open final on Friday, overcoming Alejandro Tabilo by a 1-6 7-6 (7-4) 6-2 scoreline in the last four.
Zverev was punished for a slow start as Tabilo took the opener within 32 minutes, but the German fought back in a one-hour, 15-minute slog of a second set.
The 2017 Italian Open champion put his foot down from 3-3 in the second-set tie-break, with Tabilo potentially feeling the effects of a fine run that included a last-32 upset of Novak Djokovic.
Zverev upped the intensity in the final set and won a huge 94 per cent of points behind his first serve as his opponent wilted, the third seed reaching the Rome final for a third time.
Data Debrief: Zverev draws level with Becker
Zverev will now face either Nicolas Jarry or Tommy Paul in Sunday's final, which will be his 11th at ATP 1000 Masters level.
That tally pulls him level with Boris Becker for most such finals by a German player since the format's 1990 introduction.
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