UEFA has launched an investigation after Sevilla goalkeeper Marko Dmitrovic was punched by a PSV fan during Thursday's Europa League match.
The on-field skirmish came near the end of the game, which saw PSV win 2-0 but suffer a 3-2 aggregate elimination against their LaLiga opponents.
Dmitrovic pinned down the pitch invader and held him to the ground before security arrived to escort him away.
UEFA is understood to have opened a case following the incident, which has been condemned by PSV, who said the fan should not have been in the stadium in the first place.
The Dutch club said in a statement: "PSV strongly condemn the incident on Thursday evening when a man invaded the pitch and confronted the goalkeeper. The person involved had already been handed a stadium ban."
PSV general manager Marcel Brands said: "This is not what we stand for at PSV. We feel ashamed and there is no place for that type of behaviour.
"We will consult the organisations involved to discuss how we can enforce stadium bans better, hopefully through reporting obligations. All PSV supporter organisations, who cheered on their team last night, unanimously and explicitly distance themselves from this disgraceful pitch invasion."
PSV said they would "await the investigations into the pitch invader made by the police and look to recover any financial damages".
Sevilla have been drawn to face Turkish Super Lig outfit Fenerbahce in the last-16 stage.
Six-time champions Sevilla are looking to extend their record haul in the competition, which began in its previous guise as the UEFA Cup, having last lifted the trophy in 2020 against Inter.
Al-Nassr 1-1 Al-Hilal: Mitrovic scores last-gasp penalty
Aleksandar Mitrovic scored a penalty in the 10th minute of second-half stoppage time as Al-Hilal denied Cristiano Ronaldo's Al-Nassr victory in a 1-1 draw.
Mitrovic netted his 27th Saudi Pro League goal of the campaign after Sadio Mane was harshly judged to have fouled Saud Abdulhamid in the area.
Mane stuck out an arm to shield the ball, catching his opponent in the throat, though the contact appeared to have been outside of the box.
Mitrovic made no mistake to keep Al-Hilal's unbeaten campaign going.
The Serbian's spot-kick cancelled out Otavio's first-minute opener, with Ronaldo having set up his compatriot.
Champions Al-Hilal remain 12 points clear of Al-Nassr at the summit of the Pro League standings.
Data Debrief: Ronaldo the provider
Ronaldo leads the scoring charts in Saudi Arabia this season, though he had to settle for an assist on Friday.
That came from the only chance he created, with the 39-year-old limited to 25 touches, though he did have four shots.
Al-Ittihad pegged back as winless run rolls on
Mohamed Sherif scored late on as Al-Ittihad's winless run in the Saudi Pro League stretched to four games after a 1-1 draw with Al-Khaleej.
Al-Ittihad have endured a miserable title defence, and with just two games remaining, the highest the big-spending, PIF-backed club can finish is fourth.
Muhannad Al Shanqiti put them ahead on the stroke of half-time, yet despite having a further eight shots and accumulating 1.07 xG in the second half, Al-Ittihad could not add another.
Their profligacy proved costly in the 81st minute, with Egypt international Sherif snatching an equaliser for 11th-placed Al-Khaleej.
Al-Tai moved out of the relegation zone with a surprise 3-1 win over seventh-placed Al-Fateh, with Bernard Mensah scoring twice.
Al-Raed, meanwhile, claimed a 1-0 win at Al-Wehda.
Data Debrief: Kante the creator?
On the day he received a surprising France recall, N'Golo Kante created three chances for Al-Ittihad, leading the team.
On the flip side, Kante only attempted one tackle, with the midfielder showing a different side to his game, not that it proved fruitful for his team.
Ronaldo motivated to keep playing at top level
Cristiano Ronaldo has no intention of stopping as he says he is still motivated to compete with the "young lions" coming through in the game.
Ronaldo is reportedly considering signing a contract extension to keep him at Al-Nassr until June 2026, taking him past his 41st birthday.
The Portugal international has scored 42 goals in 41 appearances for the Saudi Pro League club this season, and he insists he is still motivated to keep going.
Speaking on the Whoop podcast, he said: "I feel proud to have this age and still compete at the highest level. It's great, and it gives me motivation to carry on.
"If you look at my career for the last 20 years, my level is high. If you are top for 20 years, it's unbelievable.
"I do that, and I continue to do that. For me, it's a big achievement."
Ronaldo has scored an incredible 891 goals in his career and is the all-time leading scorer in men’s international football with 128 goals.
"My biggest motivation is to carry on," he added. "It's not easy to be at this level.
"To still push, to still motivate, to carry on, to score goals, to be in good shape, to compete with the young lions that are coming and that when they play against me, they want to show me that they are stronger and faster than me.
"You have to prepare very well, not just physically but mentally, too. This is the challenge.
"Talent without work is nothing and work without talent is nothing. They have to work together at the same time. I have both. I can't say that I have more of one than the other.
"Small details will make the difference. Consistency is the most difficult thing.
"Are you willing to do that? That's the main point, because everyone wants to be Cristiano, but doing it is difficult. Discipline is the most difficult thing."
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