Milan withstood Rafael Leao's red card early in the second half to beat Sampdoria 2-1 and maintain their unbeaten start to the Serie A season.
Stefano Pioli's champions were dominant in the first half at Stadio Luigi Ferraris and went in at the break a goal up thanks to Junior Messias' early strike – his first of the season.
However, Leao received a second yellow card two minutes after half-time for a high foot, giving Samp the impetus to level through Filip Djuricic shortly before the hour mark.
Rather than concede again, though, Milan snatched all three points in the 67th minute when Olivier Giroud slammed in from the penalty spot after Gonzalo Villar had handled in the area.
The Rossoneri went ahead in the sixth minute when Messias finished from 12 yards following a flowing move involving Giroud and Leao, although goalkeeper Emil Audero will feel he should have done more.
Djuricic whipped against the crossbar from 20 yards soon after, before Charles de Ketelaere was denied a first Milan goal when his bundled effort was ruled out for offside after a lengthy VAR review.
Milan were dealt a blow immediately after the break when Leao received a second booking after he struck Alex Ferrari in the face when attempting an overhead kick.
And Samp took advantage of their numerical advantage in the 57th minute when Djuricic headed home Tommaso Augello's cross inside the six-yard box.
But Milan had the final word as Giroud hit the roof of the net from 12 yards after the VAR had spotted a handball by Villar, prompting a pitchside review from referee Michael Fabbri.
Samp still came agonisingly close to rescuing a point in a late scramble as Mike Maignan twice denied Manolo Gabbiadini either side of a Fabio Quagliarella effort that struck the post.
Instead, a frustrating defeat ended with coach Marco Giampaolo sent off for remonstrating with Fabbri.
Giroud leaving Milan at end of season to join MLS
Olivier Giroud announced he will be leaving Milan to join the MLS at the end of the season when his contract expires.
The Frenchman joined the club in July 2021 from Chelsea, winning the Serie A title in his first season.
Giroud has scored 48 goals in 130 games in all competitions for Milan, netting 16 of those this season to help them to a second-place finish.
In an emotional interview with the club’s media channels, Giroud said: "I'm here to tell you that the next two games will be my last for Milan. My career will continue in MLS.
"I'm very proud of everything I've done here at Milan across three seasons. It's the right time to announce it. I'm a bit emotional. My story with Milan ends this season, but Milan will forever remain in my heart."
Though Giroud did not confirm which team he would be joining in the MLS, previous reports suggested he could be moving to LAFC to link up with his France international team-mate, Hugo Lloris.
Beckham: Man Utd's problems have lasted 'too long'
David Beckham believes Manchester United’s issues have lasted "too long" since Alex Ferguson’s retirement in 2013.
The Red Devils have won just four major trophies since Ferguson’s departure, with their most recent – an EFL Cup win last season – ending a six-year wait for silverware.
United have not won a Premier League title since the Scot’s final season in charge, with six managers failing to reclaim the top-flight crown since then.
This season, Erik ten Hag’s side are at risk of recording their lowest league finish and points tally, as they sit eighth on 54 points with two games remaining.
Beckham, who won 13 trophies, including six Premier League titles and the Champions League, told The Athletic: "I think it has been a difficult time over the last five or ten years, but it was always going to be when the boss left the club.
"It wasn’t just that, we lost players like Ryan Giggs, Roy Keane and Gary Neville, all of these players that had been at United for so long; you lose part of that, and you lose part of the club.
"So it was always going to be a difficult time. But we’d like it to change pretty quickly because I think it’s gone on for too long now."
United have lost 19 games in all competitions this season, their most since 1977-78 (also 19), with nine of those coming at Old Trafford – their joint-most at home in a season and the first time it has happened in the Premier League.
Their 1-0 defeat to Arsenal on Sunday marked the first time they had conceded in 10 successive games in all competitions since October 2021, while the 82 goals they have let in this season is their most since 1970-71 (also 82).
Beckham was speaking at the premiere of 99, the Amazon Prime documentary covering United’s iconic treble-winning season 25 years ago.
Madrid will use LaLiga run-in to prepare for Champions League final - Ancelotti
Real Madrid have already secured their 36th LaLiga title but head coach Carlo Ancelotti is keen to make the most of the remaining games in the build-up to next month's Champions League final against Borussia Dortmund.
Madrid are attempting to win a third trophy this season, having also lifted the Supercopa de Espana in January, and Ancelotti says Tuesday's home match against mid-table Alaves will be a big part of their preparations.
"We have to take advantage of these games in order to build some momentum," Ancelotti told reporters on Monday following Madrid's 4-0 victory at Granada on Saturday.
"Those who were rested against Granada will play tomorrow. We'll use it to get into a rhythm and good motivation ... the aim is for the whole squad to be at full strength."
Ancelotti said the matches will give players like goalkeeper Thibaut Courtois and defender Eder Militao, who have recently returned from long-term injuries, game time before the June 1 final.
"[Militao] needs to play more minutes. He's progressing very well, he's getting better every game. Hopefully, he can be at his best for the final," added the Italian. "We'll make the necessary decisions the week before the final."
Madrid are unbeaten in all competitions since January and have 90 points from 35 LaLiga games, 15 more than second-placed Girona with three league matches left.
"After the game against Alaves I'm going to give them three days' rest," Ancelotti added. "We'll then have two weeks to prepare well for the final, but the team needs to rest after such a demanding season."
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