Senegal's forwards need to step up in Sadio Mane's absence if the Lions of Teranga are going to progress in the World Cup, says Aliou Cisse.

Bayern Munich forward Mane was ruled out of the tournament after suffering a fibula injury.

The former Liverpool star is Senegal's talisman, and was crucial to their Africa Cup of Nations success earlier in 2022.

In his absence, Senegal turned in a spirited display against the Netherlands in their opening Group A game on Monday, yet fell to a 2-0 defeat.

This was despite mustering a higher expected goals (xG) total than their opponents (0.9 to 0.7) and having more shots (15 to 10).

With hosts Qatar next up at Al Thumama Stadium, head coach Cisse has demanded more from his forwards, particularly Ismaila Sarr and Diatta.

Cisse said: "We are disappointed, we had two or three very good chances [against the Netherlands]. 

"We needed to be more effective. Ismaila and Krepin are responsible there, but of course, the absence of Mane is a problem for us. Our attackers are good and we know what they are capable of.

"We need to work on it, with Ismaila and the others. We expect a lot from him and Krepin."

Qatar also suffered a 2-0 defeat in their opening match, going down to Ecuador. 

They did not register a shot on target in that match. Since 1966, the only side to fail to land a single shot on target in consecutive World Cup games is the United States, doing so against the Czech Republic and Italy in the 2006 edition.

"There's no excuse, we want to congratulate our opponents, they deserved to win," said coach Felix Sanchez.

"There is a lot of room for improvement. Maybe the responsibility and nerves got the best of us. We didn't start well. It was a terrible start."

PLAYERS TO WATCH

Qatar – Akram Afif

Qatar failed to deliver in the tournament opener, but in Akram Afif they have a quality forward who could turn the game in their favour.

Afif created only one chance against Ecuador, and Qatar need to find a way to get him into the game more this time out.

Senegal – Ismaila Sarr

Sarr had more shots (three) and created more chances (four) than any other Senegal player against the Netherlands, with the Watford attacker involved in 47 per cent of their total attempts in the match (7/15).

With his coach's words no doubt ringing in his ears, Sarr will be determined to prove he can cut it in Mane's absence.

PREDICTION

Senegal are the favourites for this one, according to Opta, who give the Africa Cup of Nations champions a 59.1 per cent chance of victory.

The draw is given a 24 per cent chance, with the likelihood of a Qatar win only 16.9 per cent.

Sadio Mane remains a key influence on Senegal's World Cup campaign despite his absence, with Kalidou Koulibaly revealing the forward is in constant contact with the national team.

The Bayern Munich attacker was ruled out of Qatar 2022 after undergoing surgery for a leg injury sustained on November 8 in a Bundesliga game with Werder Bremen.

It has been a cruel blow for player and country, with Mane's penalty having been the victorious touch to take Senegal to Qatar 2022 in their qualifying play-off earlier this year against Egypt.

But despite his absence, Koulibaly says the forward is still a regular, virtual presence around the squad, helping to raise their game and keep them focused.

"He's always texting with us, always calling," he stated. "[He is] keeping the mentality high for the team. He's an important player for us.

"We know the importance that he has for the team and we hope he will continue [to stay in touch]. When he speaks, all of Senegal listens."

Senegal came up short in their first match of the World Cup on Monday against the Netherlands, conceding a pair of late goals to suffer a 2-0 defeat

Ahead of Friday's encounter with hosts Qatar in Group A, the Lions of Teranga are looking to get their campaign back on track, with Koulibaly stating they are stung by loss.

"It is very difficult after a defeat to get your head around things," he added. "It is a difficult pill to swallow. We've started off with a loss."

Both concessions marked a tough game for goalkeeper Edouard Mendy, with Senegal's first-choice goalkeeper having endured a hit-and-miss campaign with Chelsea.

Blues team-mate Koulibaly remains unconcerned over any fears of a dip in form however, adding: "We're brothers in arms. He's an important player for us.

"It's normal to go through difficult periods, but I think we're making a mountain out of a molehill. Edouard knows what he needs to do tomorrow, as do we. I don't think we should be making a big deal about this.

"Everyone needs to be confident in our role; everyone needs to get stuck in. It is together that we are going to be able to overcome this hurdle. I am not worried."

Cameroon forward Eric Maxim Choupo-Moting is sad for Senegal, Africa and Sadio Mane after his Bayern Munich team-mate was ruled out of the World Cup.

African player of the year Mane was initially expected to feature in Qatar and was named in Senegal's 26-man squad, despite sustaining a leg injury in Bayern's 6-1 win over Werder Bremen on November 8.

But the former Liverpool forward saw his World Cup dreams shattered last Thursday as Senegal confirmed surgery would be required for the 30-year-old's fibula issue, thus ruling him out of the tournament.

Choupo-Moting and Cameroon face Switzerland in Thursday's Group G opener but much of the striker's focus appeared to be with team-mate Mane.

"I'm very sad for him, and for both Senegal and for Africa. He's a great player and a great person as well," Choupo-Moting said on Tuesday.

"I'm very happy that he joined us at Bayern. I'm very, very upset and sad for him that this injury came just before the World Cup.

"Injuries are always part of the game, unfortunately, I don't know why it came at the wrong moment but we are all with him. 

"He's a positive guy who will keep his positive energy. I hope he will come back stronger."

Cameroon have lost their last seven games at the World Cup (between 2002 and 2014), with only Mexico losing more consecutive outings at FIFA's top tournament, nine from 1930 to 1958.

But Rigobert Song's side impressed with 14 goals at the Africa Cup of Nations, five more than any other team, and the most at the competition since Egypt in 2010 (15).

Choupo-Moting has also managed a talismanic nine goals in 14 games for Bayern and he expects his hard work to pay dividends for Cameroon in Qatar.

"There's no secret, it's work; you have to work and believe in yourself," he added. "I know my qualities. I know I have a lot of qualities and with my team-mates, each one can make a difference. 

"There is always this pressure, every game is important and Cameroon expects us to win every game. We concentrate game after game. First, it's Switzerland and then we'll see."

Argentina's World Cup hopes took a shuddering blow in their Qatar 2022 opener as they were sensationally beaten 2-1 by Saudi Arabia.

Having won the Copa America last year and embarked on a 36-match unbeaten run, La Albiceleste arrived in Qatar as one of the favourites to be crowned world champions.

Lionel Messi's penalty gave them an early lead in their first Group C match at Lusail Stadium, but second-half goals from Saleh Al-Shehri and Salem Al-Dawsari ensured Saudi Arabia pulled off a huge upset.

Here, Stats Perform takes a look at five of the other monumental World Cup shocks over the years.

Senegal 1-0 France (Korea/Japan 2002)

Perhaps the all-time upset in World Cup history, France headed to the 2002 edition four years on from a triumph on home soil with a squad brimming with talent and set on defending their crown.

Yet in the opening match, Les Bleus - without talisman Zinedine Zidane - were stunned by Senegal, the competition's lowest-ranked side, thanks to Papa Bouba Diop's first-half finish in Seoul.

France went on to finish bottom of Group A with just a draw against Uruguay to their name, and failing to score a single goal.

North Korea 1-0 Italy (England 1966)

Arriving in Europe for their first appearance at the World Cup, North Korea were widely expected to make an early exit after a defeat to the Soviet Union and a draw with Chile.

But Pak Doo-ik made history when his lone goal saw them shock two-time winners Italy at Ayresome Park in Middlesbrough.

North Korea have only been back to the World Cup once, at South Africa 2010, where they scored once and conceded a dozen, finishing bottom of Group G.

Cameroon 1-0 Argentina (Italy 1990)

This is not the first time La Albiceleste have been involved in one of the most unexpected results at a World Cup, having been stunned in the first match of their title defence over three decades ago.

Argentina arrived at Italia 90 looking to defend the crown Diego Maradona guided them to four years prior, but Francois Omam-Biyik's 67th-minute goal at San Siro left them shell-shocked.

USA 1-0 England (Brazil 1950)

Heading into their tournament debut in South America, England were fancied to make a big impact, particularly when they came up against a United States team dominated by part-timers.

But a goal for Joe Gaetjens made history for the USA, bringing England back down to earth after they started with a 2-0 win over Chile.

Walter Winterbottom's men were then on their way home after slumping to a 1-0 loss at the hands of Spain.

Northern Ireland 1-0 Spain (Spain 1982)

Fondly remembered four decades down the line, Northern Ireland's win against tournament hosts Spain ranks among the greatest in their history, as they defied the odds in Valencia.

Gerry Armstrong's goal early in the second half put then in front and although Mal Donaghy was shown a red card, Billy Bingham's team hung on to deliver an almighty upset.

Louis van Gaal says the Netherlands will assess Memphis Depay's fitness following his cameo in their victory over Senegal.

The Oranje marked their return to the World Cup finals with a 2-0 win over the Africa Cup of Nations champions, with late goals from Cody Gakpo and Davy Klaassen sealing the points in Group A.

Depay began the game on the bench due to an ongoing hamstring issue, but was introduced for the final 28 minutes at the Al Thumama Stadium and the Barcelona forward will hope to feature against Ecuador on Friday.

"We had agreed before the game that he would play about half an hour," Van Gaal said of Depay, who has been limited to just two LaLiga appearances this season. 

"With Ecuador, he will want to play, but I have to assess his form after this game. I never thought we would lose and, with the entry of Depay, I wanted to have more chances to score. He is a player who can make the difference."

Van Gaal oversaw his 38th victory in charge of the Netherlands, the most by any manager in history, and praised the displays of Gakpo and goalkeeper Andries Noppert, who registered a clean sheet on his senior international debut.

But the head coach is seeking an improvement from his players as the tournament progresses.

"Gakpo was decisive, I left him inside because he knows how to score goals and is very agile," he added. "Senegal had three chances, but we have a goalkeeper who knows his stuff between the posts.

"We didn't play very well, too many times we gave them the ball and the chance to score. We had to be more compact. We can only improve, there was probably some tension between the players."

Memphis Depay was frustrated to be restricted to the role of a substitute in the Netherlands' World Cup opener, but he is confident of having a greater impact in coming matches.

Depay had been ruled out of Monday's match against Senegal in Louis van Gaal's pre-match news conference.

But the Barcelona forward appeared on the bench and was introduced in the final half an hour with the game still goalless.

Although Depay did not get on the scoresheet, he was involved in the build-up to both Oranje goals in a 2-0 win, with Cody Gakpo scoring the first before Davy Klaassen tucked away the rebound from the Netherlands number 10's shot.

Speaking afterwards, Depay said: "I feel good, I feel good, I feel fit. Obviously a player like me always wants to start from the kick-off, but this was the plan and now we focus on the next game.

"I'm sure that I'll feel better, and I'll work hard to find more rhythm. I'm happy that I could do a little bit of a part in 30 minutes today."

On Gakpo, who benefited from Depay's absence and was preferred to Klaassen, he said: "I'm very happy for him. He's a hard worker, he's very dedicated in his career. He's a young baller.

"I'm very happy. He's a great guy, a young guy, lots to learn, so I'm sure you'll see more moments like this."

Despite missing out on the XI, the stoppage-time clincher was also a big moment for Klaassen.

"It's a dream, of course," he said. "It's my first World Cup game, so to score your first World Cup goal and to win... you can't ask much more."

Klaassen was also asked about the OneLove captain's armband, which Virgil van Dijk had been due to wear until FIFA threatened sanctions.

The campaign promotes "inclusion and sends a message against discrimination of any kind", but those planning to wear the armband feared they would immediately be shown a yellow card.

"We're still behind the statement," Klaassen added. "FIFA forced us to not wear it, but the statement is still there."

Van Dijk himself did not appear impressed by discussion of the topic, saying: "You know exactly what the outcome was.

"Two hours before the England game, the news came out, and I was sleeping at the time. I had no influence on anything.

"I'm not dealing with the armband because I don't want to get a yellow card."

Cody Gakpo says the Netherlands "can do much better" after his late goal helped them to a 2-0 win against Senegal in their World Cup opener.

The Oranje needed a late intervention from the PSV man to get them over the line against the Lions of Teranga, before Davy Klaassen added a second in injury time.

It marks a winning return to the World Cup for Louis van Gaal's side, who missed out on the last tournament in Russia.

But despite a victorious start in Group A, Gakpo feels there is room for improvement after an otherwise scrappy performance.

"We weren't careful enough with the ball," he told broadcaster NOS. "I think we can do much better. We were good in our possession. We have to analyse this properly and take the good points to the next game.

On his goal though – a rare headed finish – Gakpo was more effusive, adding: "This gives you a good feeling. We were really looking for it as a team, so it's great that it still works!"

With a dearth of clear-cut chances throughout, it was a relatively painless debut performance for Dutch goalkeeper Andries Noppert between the posts.

The shot stopper was happy to get his first game under his belt, and believed the Oranje showed their mettle in taking victory despite a rough all-around game.

"It is special to make my debut," Noppert said. "You dream of this. I never thought it was possible. As a little boy, this is a dream – you don't assume it [will happen].

"Our game as a team was not good, but then it is great if you can still find a way to win. We want to go very far and become world champions. Otherwise, we shouldn't come."

Late goals from Cody Gakpo and Davy Klaassen gave the Netherlands a 2-0 win over Senegal in their World Cup return at the Al Thumama Stadium on Monday.

The Oranje had produced a lacklustre performance in their first World Cup match since the 2014 tournament in Brazil, but secured all three points.

With just six minutes of regulation time left on the clock, Gakpo raced into the box and rose in front of Edouard Mendy to meet Frenkie de Jong's cross with a header to break the deadlock.

Louis van Gaal’s side were not convincing, but they had a second goal deep into stoppage time when Klaassen slotted home right at the end of a disappointing Group A contest.

Sadio Mane is backing Senegal's Lions of Teranga to show they still have sharp claws without him in Monday's World Cup opener against the Netherlands.

Bayern Munich forward Mane was set to spearhead the team's quest in Qatar, but a cruel leg injury has ruled him out of the tournament.

On paper, it seems the team are significantly weakened by his absence, but Mane says the reality could be rather different, backing the group he left to rise to their challenge.

The former Liverpool star wrote on Instagram: "This Monday, our dear country will compete in the World Cup, Qatar 2022. I am sure the Lions will transcend and approach every game as a true final.

"I am also convinced that all Senegalese will be in front of the small screen to support and encourage our valiant national team.

"Like all supporters of the 'Taniere' [lions' den], I am convinced that my team-mates will fight as one man and as they usually do to honour our dear Senegal. Long live Senegal, come on the Lions."

Senegal were surprise quarter-finalists in 2002, and as reigning Africa Cup of Nations champions they were considered by many as the continent's biggest hope for World Cup success this time around.

Losing Mane will change that perception for many observers.

The 30-year-old had a tendon reattached to the head of his right fibula after being ruled out of Senegal's squad, and he could face several months on the sidelines.

Mane thanked well-wishers, writing: "Many of you have sent messages of support following my injury. Thank God, the surgery I had in the middle of the week went well. I want to take this opportunity to thank and show my appreciation to you all."

Virgil van Dijk was saddened to hear his former Liverpool team-mate Sadio Mane would miss the World Cup, but he hopes the Netherlands will profit from the Senegal star's absence on Monday. 

Africa Cup of Nations champions Senegal suffered a huge blow on Thursday, when it was confirmed Mane would not recover from a fibula injury in time to feature at the tournament.

Mane has been directly involved in 12 of the last 25 goals scored by Senegal players at either the Africa Cup of Nations or the World Cup, leading coach Aliou Cisse to concede the Lions of Teranga would have to cope without their best player in Qatar.

Although Van Dijk acknowledges Mane's woes could benefit the Netherlands in Monday's Group A meeting, he has been in touch with the Bayern Munich attacker and pities his misfortune.

"I called him the next day. I wanted to know how he was, first and foremost, because there were so many rumours that he was out for a while," Van Dijk said of his reaction to Mane's injury.

"As a friend, I wanted to know how he was. Unfortunately, at the time, he'd already not had the best of news, but there was a little bit of hope, everyone thought.

"Unfortunately, he won't be able to make this tournament and I feel sad for him. I know how hard he worked for this. He wants to be important for Senegal and he has been important for them, in the last couple of years especially.

"It's tough. Obviously he's going to be a big miss for them, and hopefully we can benefit from that a little bit as well."

Although the Netherlands failed to qualify for the 2018 tournament in Russia, they have won 11 of their last 14 World Cup matches (D2 L1), with their only loss during that run coming in 2010's final against Spain.

Aliou Cisse vowed Senegal "will leave our mark" at the World Cup as they look to extend their perfect opening-game record at the tournament when they face the Netherlands.

The reigning African champions have won their previous two openers – a shock 1-0 win over France in 2002 and a 2-1 victory against Poland in 2018.

Senegal reached the quarter-finals 20 years ago, but they were eliminated in the group stage in the most recent edition and Cisse is hoping for a different outcome this time.

"The aim is to get out of this group. Once we get out of this group, we know that it will be a knockout tournament," he told reporters. 

"We will leave our mark. People are already looking ahead to the last 16, the quarter-finals, but we will be taking it a game at a time.

"We're not getting carried away. It's up to us to fully prepare ourselves and to do so wisely. We were knocked out of the last World Cup after just three games."

Senegal defeated Egypt in February to win their first Africa Cup of Nations title, before beating the same side the following month in a World Cup qualifying play-off.

Cisse's side are ranked 18th in the world – 10 places behind the Netherlands – and are without star man Sadio Mane in Qatar due to injury.

Senegal may have a perfect opening-game record, but the Netherlands are unbeaten in their past eight curtain-raising matches, winning six of those.

Oranje are back on the world stage after failing to qualify for Russia 2018, with veteran boss Louis van Gaal now in his third spell in charge.

Van Gaal, who will step aside at the end of the tournament, admits his side will need more than just talent to go all the way in Qatar and lift the trophy for the first time.

"I don't believe we have the best players on earth in our team," he said. "But I believe in team building and in tactics. I believe we can go far.

"But we also need luck – that is also important. Because of that and because I believe in imagination, we could be the world champion at the end of the tournament."

Monday's Group A contest at Al Thumama Stadium will mark the first time Senegal and three-time World Cup runners-up Netherlands have met.

Oranje are unbeaten in four matches against African opposition in the finals, while Senegal have won two and drawn one against European sides in the group stage.

PLAYERS TO WATCH

Senegal - Boulaye Dia

Losing Mane to injury just before the tournament was a cruel blow for Senegal, the forward having been directly involved in 12 of their past 25 goals in major tournaments.

It will now be down to others to step up and fill the void, such as Salernitana forward Boulaye Dia, who has been in good form at club level this campaign.

Dia has six goals in 14 Serie A matches – a tally only five others can better – and has been directly involved in eight overall for mid-table Salernitana.

Netherlands - Steven Bergwijn

Memphis Depay was the Netherlands' star man on the road to Qatar with 12 goals and six assists – those 18 direct goal involvements the most of any player in UEFA qualifying – but he has been ruled out of the Senegal match.

Van Gaal has a number of other options in attack, however, with Bergwijn one of them.

The Ajax winger has eight goals and three assists in 14 Eredivisie matches this campaign, and  six goals in his past nine appearances for his country, making him one Van Gaal can rely on.

PREDICTION

The Netherlands have won 11 of their past 14 matches at the World Cup, penalty shoot-outs excluded, with their most recent group-stage loss coming in 1994 against Belgium.

Senegal are tricky first opponents for Oranje, but Stats Perform's AI model has given the Netherlands a 59.2 per cent chance of taking all three points in Al Thumama.

The prediction model gives Senegal a 17 per cent chance of victory, while a draw is rated at 23.8 per cent.

Aliou Cisse concedes Senegal will be without their best player heading into the World Cup but insists his squad are "ready for the challenge".

The African champions suffered the crushing news that star man Sadio Mane would miss the tournament after having to undergo surgery on a fibula injury sustained in Bayern Munich's 6-1 thrashing of Werder Bremen 12 days ago.

Mane's importance to Senegal is highlighted by the fact he has been involved in 12 of the last 25 goals scored by Cisse’s team in the finals of either the World Cup or Africa Cup of Nations.

And his absence has forced a tactical re-think ahead of Monday's opener against the Netherlands at the Al Thumama Stadium in Doha.

Cisse said: "Obviously it's a great shame for Sadio and the team, but we have to think of the player's well-being.

"It's a great challenge as all coaches build their team around the best player and that's the case for us.

B"ut we have a strong team with experienced players and young players who are ready to rise to this challenge. I am sure we have a strong enough team. It's not easy to play without a player like Sadio and we have a strong opponent in the Netherlands, but the players are ready.”

Senegal winger Krepin Diatta was a little less bullish, admitting Mane's absence had had an impact within the squad.

The Monaco man said: "Sadio is an extremely important player for our team and we are determined to do what we can without him.

"But of course it affects you, he is our best player and leader. We'd like him to be here, but God decided otherwise.”

Senegal disappointed in exiting the 2018 World Cup in Russia at the group stage, but Cisse believes that experience – and their AFCON triumph earlier this year – stands them in good stead to go further in Qatar.

"In 2018, it had been such a long time since Senegal had been to a World Cup, and we are now getting another chance," he added.

"We are African champions and we have new, excellent players that have strengthened the squad. Hopefully the mistakes of Russia won't be repeated."

In the opposing dugout on Monday will be Louis van Gaal, a man Cisse described as a "benchmark", and the former Paris Saint-Germain midfielder believes guiding his team to successive World Cups is another shot in the arm for African coaches, five of whom are present in Qatar.

He said: "It's progress that we have been seeing for some years now. We are aware that people are looking at us. If we lose in the first round, people will say we aren't good enough.

"I was born in Senegal – it's important to understand the realities of the country you are managing. We are proud to represent African coaches and it's a message we are sending them that they can also be at the highest level."

Memphis Depay will not feature in the Netherlands' World Cup opener against Senegal, but coach Louis van Gaal remains optimistic for the tournament, believing this squad to be capable of improving on a third-placed finish at Brazil 2014.

Depay had been a doubt for Monday's match in Doha due to a hamstring injury that has limited him to only two LaLiga appearances at Barcelona this season.

Oranje coach Van Gaal, speaking to the media on Sunday, confirmed the forward would miss out against Senegal, suggesting his "idea of the match" centred around how the two teams would fare without their respective stars. Senegal's Sadio Mane is out of the entire tournament.

Depay was involved in more goals in European qualifying for Qatar 2022 than any other player, scoring 12 and assisting a further six in just 10 matches.

Van Gaal said: "Mane can break open a match, and I would say Senegal will really miss him. But the same applies to us. We are really missing our top scorer and the king of the assists."

However, the Netherlands boss had been aware a swift return was unlikely for Depay, adding: "We knew before the World Cup he had a different programme, a different schedule than the schedule of a player who is preparing for a match."

When he recovers, Depay will be tasked with leading the line for a Dutch side Van Gaal considers superior to his class of 2014 – the last team he took to a tournament in the second of three stints in the role.

The Netherlands reached the semi-finals on that occasion, losing to Argentina on penalties before beating Brazil in the third-place play-off.

Given Van Gaal's high opinion of this group of players and his own considerable experience, he expects results to follow – potentially culminating in a first World Cup triumph.

"I believe in this squad, this group of players," he said. "In 2014, we came third with a squad of lesser quality, I would say. With this group, I expect more.

"It all depends not only on technical skills and tactical skills but also a bit of luck that you score at the right time or that the others don't score.

"I think we could become world champion, but there are squads that are in my view of a higher level than my squad. The thing is how the squad deals with that, and there I think I may be able to benefit from a head start.

"I'm saying we can become world champion. Whether we become world champion is a separate issue, but I'm saying we can."

While Van Gaal would not confirm the identity of his starting goalkeeper, he hinted at Cody Gakpo getting the nod ahead of Davy Klaassen in Depay's absence, and there is no doubt who his captain is.

Van Dijk appeared next to Van Gaal, who said: "I have a wonderful captain next to me. I have worked with so many captains, and he is a truly great captain. That makes things easier."

But neither Van Dijk nor Van Gaal would answer political questions after Gianni Infantino's remarkable opening address the previous day.

"I am no longer going to speak about political issues," the previously outspoken Van Gaal said. "I'm focusing on this coming match.

"I put a full stop after all these issues after we invited the migrants to watch our practice session. I requested all my players also stopped doing that and put a full stop and focus on the match against Senegal."

The World Cup in Qatar is finally set to get underway, but there are a number of major players who will be watching along with the fans back home.

An unfortunate reality about the tournament is there will always be significant absences, either through a nation's failure to qualify or due to injury.

It is the latter that has been a major focus in the final week before Sunday's kick-off, with Senegal star Sadio Mane and France striker Karim Benzema both being late withdrawals from their respective squads, the latter suffering a quadriceps injury on Saturday, depriving the tournament of the 2022 Ballon d'Or winner.

Benzema's injury is just one of several significant blows for holders France, and they dominate Stats Perform's injured XI of the players unable to feature in Qatar.

Goalkeeper: Mike Maignan (France)

Maignan had a fine maiden season at Milan after joining from Lille. He kept 17 clean sheets in Serie A last term, the highest tally in the league, and conceded just 21 goals, with his save percentage of 79.4 the best of any Serie A goalkeeper to play more than 10 games in the competition.

He has made seven appearances this season, but the 27-year-old suffered a calf injury in October, leaving Didier Deschamps shorn of a quality shot-stopper to challenge Hugo Lloris.

Defence: Ben Chilwell (England), Reece James (England), Presnel Kimpembe (France)

Chelsea duo Reece James and Ben Chilwell were by no means guaranteed to start for England, but it's still a blow to Gareth Southgate not to have the pair available.

James has excelled at wing-back and would have been an ideal fit if England stick with a three-man defence, while he could also have slotted in at centre-back, and Chilwell would likely offer more attacking threat than Luke Shaw on the left should the Three Lions have needed to chase a game.

Paris Saint-Germain defender Presnel Kimpembe helped France win the 2018 World Cup, but he had to withdraw from Deschamps' squad for Qatar due to an Achilles problem.

Midfield: N'Golo Kante (France), Giovani Lo Celso (Argentina), Paul Pogba (France), Georginio Wijnaldum (Netherlands)

Giovani Lo Celso was not always a key player for Tottenham but retained his place as a crucial cog for Argentina. La Albiceleste will be without the midfielder, who sustained a hamstring injury while playing for Villarreal against Athletic Bilbao late in October.

Georginio Wijnaldum scored three goals in four games for the Netherlands at Euro 2020, but shortly after joining Roma on loan from PSG, the former Liverpool midfielder suffered a fractured tibia and had no chance of recovering in time to make Louis van Gaal's squad.

Another two France stars complete the midfield, with Paul Pogba and N'Golo Kante missing for Les Bleus. Both players were exceptional in 2018, but Kante is out with a hamstring problem, while Pogba is yet to make an appearance for Juventus this season after joining from Manchester United.

Attack: Karim Benzema (France), Sadio Mane (Senegal), Christopher Nkunku (France)

It's fair to say France have been hit hardest by injuries to big players, and there could arguably be none bigger than Benzema, the Ballon d'Or holder. Given he is 34, it could well have been the Real Madrid striker's final shot at a World Cup and is a huge blow not only to France but to football fans around the world who were highly anticipating the Benzema-Kylian Mbappe link-up.

A player who might have softened the blow of Benzema's injury was Christopher Nkunku, had he not already been ruled out himself with a knee issue sustained in training last week, just before Les Bleus left for Qatar. Nkunku has been in sensational form for RB Leipzig, with only Mbappe of players from Europe's top five leagues having scored more goals (58) since the start of last season than the RB Leipzig star, who has amassed 52 in 75 games.

Mane, meanwhile, was carrying the hopes of Senegal on his shoulders. The Africa Cup of Nations holders have a talented squad, but Mane was the stardust. He went down with an injury to his fibula while in action for Bayern Munich just before the World Cup break, and though Senegal named the ex-Liverpool attacker in their squad, he underwent surgery earlier this week and was duly ruled out.

Sadio Mane could face several months on the sidelines after undergoing the surgery that ended his slim hopes of playing for Senegal at the World Cup.

The Bayern Munich forward underwent what his club described as a successful operation on Thursday.

Bayern said in a statement: "During the operation, a tendon was reattached to the head of his right fibula.

"The FC Bayern forward will therefore no longer be available to play for Senegal at the World Cup and will begin his rehab in Munich in the next few days."

According to widespread reports in Germany, Mane's recovery is unlikely to be a quick one, with the former Liverpool forward said to be facing possibly three to four months out of action.

African player of the year Mane sustained the leg injury when playing in Bayern's 6-1 win against Werder Bremen last week.

He was initially judged fit enough to be included in Aliou Cisse's 26-man Senegal squad for the World Cup, with hopes he could be available by the knockout stages, but subsequent medical checks confirmed the need for surgery.

A short statement from the Senegalese Football Federation read: "The FSF wishes a speedy recovery to its player Sadio Mane."

Senegal face Netherlands in their Group A opener on Monday before meeting Qatar and Ecuador.

Bayern are due to resume their Bundesliga campaign against RB Leipzig on January 20. They headed into the World Cup break as leaders, chasing an 11th consecutive German league title.

They face a Champions League last-16 tie against Paris Saint-Germain, with games scheduled for February 14 and March 8 in that heavyweight contest.