Joel Embiid's injury last week appeared to clear a path for LeBron James to collect his fifth NBA MVP award.
Philadelphia 76ers big man Embiid - averaging 29.9 points and 11.5 rebounds, as well as 1.4 blocks and 1.2 steals - had already missed seven games this season before he went down with a knee injury against the Washington Wizards.
But Los Angeles Lakers superstar James did not see his clear run at the league's top individual honour last long.
James, who has 25.9 points, 7.9 assists and 7.9 rebounds per game, has carried the Lakers in Anthony Davis' absence but faces his own spell on the sidelines after an ankle sprain on Saturday.
That setback, in a defeat to the Atlanta Hawks, means this year's two leading MVP contenders face an uphill task to remain in contention as they sit out a key stretch of the regular season.
Nikola Jokic, the Denver Nuggets center, appears the man most likely to profit and has quickly been installed as the bookmakers' favourite.
But with several twists already in the race to succeed back-to-back winner Giannis Antetokounmpo, Jokic's standing is not yet safe.
With the help of Stats Perform data, we run through four potential winners ahead of Sunday's action - including Denver's 'Joker'.
NIKOLA JOKIC
The case against Jokic earlier in the season was his displays had not been able to lift the Nuggets into serious contention in the West. With 13 wins in their past 18 games to improve to 25-16, that is no longer the case.
While team-mate Jamal Murray has not been able to consistently perform at the standard he set in the 2019-20 playoffs - averaging 26.5 points in the 'bubble' but 21.1 this season - Jokic has taken his game to another level.
The Serbian's stat line for the year - 27.0 points, 8.6 assists, 11.2 rebounds and 1.6 steals - has never previously been achieved in league history, nor has any player in the past attempted at least 30 field goals across a season while shooting 56.6 per cent from the field, 41.6 per cent from three and 86.6 per cent of free throws.
This is an unprecedented campaign.
DAMIAN LILLARD
Tied with Denver at 25-16 in the West are the Portland Trail Blazers. Considering CJ McCollum has only played 16 games and Jusuf Nurkic 12, that is a quite remarkable achievement, led, of course, by Lillard.
Understandably, Lillard's usage rate is at a career-high 33 per cent, but he is making the most of those extra touches. Only Bradley Beal (32.5) has outperformed his 30.6 points per game - another career benchmark - and the Blazers star leads the league with 1,225 total points. Of those, 136 have come in 'clutch' situations, again putting Lillard at the top of the standings.
Taking a break from Portland's playoff push, Lillard even preserved enough energy to score 32 points in the All-Star Game, just ahead of Team LeBron team-mate and rival Stephen Curry (28). An MVP triumph would certainly see Portland's finest emerge from the shadow of the Golden State Warriors great.
GIANNIS ANTETOKOUNMPO
Antetokounmpo beat James Harden to this award in 2018-19 and then LA's James last season, so a case of voter fatigue was always set to make him an unlikely winner for a third straight year, regardless of performances.
But with Embiid and James both hit by injuries, the 'Greek Freak' surely has to come into consideration. Once again, his numbers are seriously impressive.
The only man to outscore Lillard at the All-Star Game, putting up 35, Antetokounmpo is slightly down on last year's points (29.0 versus 29.5) and rebounds per game (11.7 versus 13.6) but has improved in all of the other key metrics with 6.4 assists, 1.2 steals and 1.3 blocks.
The Milwaukee Bucks forward should be in the picture to retain both his MVP and Defensive Player of the Year titles.
JAMES HARDEN
Surely voters will not reward Harden in the year he forced his way out of the Houston Rockets? On performances alone, though, he deserves to be in the conversation.
The 2017-18 winner is not contributing the same number of points for the Brooklyn Nets as he was in Houston, but then his usage is down to 28.7 per cent for the year (28.1 in Brooklyn), by far the lowest it has been since the statistic was first tracked in 2014-15.
And Harden, still scoring an impressive 25.4 points since joining the Nets, is more than making up for this slight decline elsewhere.
So far the most prominent member of the team's 'big three', with Kevin Durant too often injured and Kyrie Irving absent for a spell, Harden leads the league in 2020-21 for assists (11.2) and is second for triple-doubles (11), making him an unpopular but worthy candidate.
Foden: De Bruyne the best in the Premier League
Phil Foden hailed Manchester City team-mate Kevin De Bruyne as the Premier League's best player after the pair both netted in the 4-0 win over Brighton and Hove Albion.
De Bruyne opened the scoring in Thursday's contest at Amex Stadium before Foden took over with a couple of goals of his own before half-time.
Julian Alvarez rounded off the scoring just after the hour in a one-sided contest as an Erling Haaland-less City moved to within a point of leaders Arsenal with a game in hand.
Belgium international De Bruyne now has four goals and six assists in just 13 league appearances for City this season.
Speaking to Sky Sports News after the win over Brighton, Foden said: "I think when he is at it, he is the best player in the Premier League."
Foden's first goal came via a deflected free-kick that he himself won, although replays showed he slipped rather than being fouled.
The England international doubled his personal tally with a composed finish after Brighton were caught in possession at the back.
Asked about playing more centrally, Foden said: "I have always said that I see myself there. This year I have moved inside and it has helped me massively.
"I enjoy it in the middle. It's where I want to be. At the moment, I am just enjoying my football and playing with freedom."
De Bruyne had earlier opened the scoring with a brilliant opener - his first headed goal for City in the Premier League - as City made it 30 games unbeaten in normal time across all competitions.
Alvarez then went on to round off the scoring in a game that not only saw the reigning champions close the gap on Arsenal, but also narrow the goal difference margin to eight.
"It was a good game," De Bruyne said. "I think we played really good in the first half and every game is a lot of pressure. All we can do is prepare as we did today and win the game that is in front of us.
"We just want to win game-by-game and push for the title. We don't get ahead of ourselves. Now the next game is coming quickly. Try to recover and we go again."
Kyle Walker assisted the De Bruyne and Alvarez goals - the first time the defender has set up two goals in a single Premier League game in what was his 390th appearance in the competition.
Reflecting on his rare headed goal, De Bruyne said: "It doesn't happen too much. Kyle gave a good cross and I think the only way I could reach it is by jumping to it. I will take it but it's not something I am good at."
City have rather ominously won four Premier League games in a row and travel to strugglers Nottingham Forest next up at the weekend, knowing victory in their remaining five games will secure an unprecedented fourth straight title.
"I trust my team. All respect to Liverpool and Arsenal, they are amazing," De Bruyne added. "Arsenal are doing what they need to do and we are also needing to do it. Work hard and be humble enough to keep pushing."
'Let's make it mano a mano' – Adebayo using criticism as fuel as Heat level Celtics series
The Miami Heat are desperate to silence their doubters and are using outside criticism as fuel in their first-round playoff series against the Boston Heat, having levelled it up at 1-1.
That is according to forward Bam Adebayo, who had 21 points and was nine of 13 shooting in the Heat's 111-101 win at TD Garden on Wednesday.
Miami buried their hosts under a mountain of 3-pointers in Game 2, setting a franchise record for a postseason game by shooting 23 of 43 (53.5 per cent) from the field.
Speaking after the game, Adebayo said the way in which the Eastern Conference's eighth seeds have been written off by neutrals was spurring them on.
"We've been doubted a lot through our playoff runs, people saying we couldn't do a lot of stuff that we eventually did," Adebayo said.
"So for me and my team, why lose belief now? Our backs are against the wall. Everybody's against us. So just use that as fuel.
"Our guys believe we can win. So, let's make it mano a mano… a cage fight. Let's hoop!"
Caleb Martin joined Adebayo on 21 points with five 3s, being booed by the Boston crowd every time he touched the ball following his heavy collision with Jayson Tatum in Game 1.
Jaime Jaquez Jr. contributed 14 points with three 3s, Nikola Jovic added a trio of 3s and Haywood Highsmith came off the bench to sink three 3s.
Martin said Miami's new shoot-on-sight mentality was part of a plan drawn up by Erik Spoelstra, saying: "I think it was about realising that being passive hurts us.
"We'd just be playing into their gameplan. We're too good of a shooting team to hesitate from 3."
Spoelstra himself said the Heat had taken the decision to be more proactive after being sunk by Boston's 3-point shooting in Game 1.
"I understand the math of it," the Miami coach said. "We're not going to shoot 50 of them. That's not realistic."
NBA: Heat get even with Celtics; Thunder roll Pelicans for 2-0 lead
Tyler Herro had 24 points and 14 assists and hit six of Miami’s franchise playoff-record 23 3-pointers as the Heat defeated the Boston Celtics, 111-101, to even their first-round series at a game apiece on Wednesday.
Bam Adebayo had 21 points and 10 rebounds and Caleb Martin added 21 points with five 3s for the Heat, who shot 53.5 percent (23 of 43) from long range to break the franchise playoff record of 20 3s, set against Milwaukee in 2021.
Jaime Jaquez Jr. contributed 14 points with three 3s, Nikola Jovic added a trio of 3s, nine rebounds and six assists and Haywood Highsmith came off the bench to hit three 3s.
The series shifts to Miami for Games 3 and 4 on Saturday and Monday.
Jaylen Brown scored 33 points and Jayson Tatum added 28 for the top-seeded Celtics, who cut Miami’s lead to 102-96 with three minutes left. But Martin hit a 3 and Herro made a driving layup to essentially seal the win.
Tatum scored 14 points in the first quarter and showed no ill effects after he was undercut by Martin while going after a rebound in the final minute in Game 1.
Gilgeous-Alexander, Holmgren power Thunder
Shai Gilgeous-Alexander scored 33 points and Chet Holmgren added 26 to lead the hot-shooting Oklahoma City Thunder to a 124-92 rout of the New Orleans Pelicans and a 2-0 lead in their Western Conference first-round series.
Jalen Williams had 21 points, seven assists and five rebounds for the Thunder, who shot 59 percent (46 for 78) from the floor and made 14 of 29 (48.3 percent) from 3-point range.
Game 3 will be Sunday in New Orleans.
Jonas Valanciunas had 19 points and Herbert Jones and Brandon Ingram each added 18 as the Pelicans continued to struggle offensively without injured star Zion Williamson (strained left hamstring).
New Orleans missed 19 of 26 from beyond the arc and made 33 field goals to 46 for Oklahoma City.
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