Borussia Dortmund head coach Marco Rose admits he is "angry" after his side spurned a golden opportunity to win a title after crashing out of the DFB-Pokal 2-1 to St Pauli on Tuesday.

DFB-Pokal holders Dortmund conceded twice in the first half before Erling Haaland pulled back a 58th minute penalty but they could not find an equalizer in the last-16 clash.

The defeat means for the first time since 2006-07, neither Dortmund or Bayern Munich will contend in the DFB-Pokal quarter-finals, with Rose admitting it was a major missed opportunity.

"I'm just angry. The cup is a chance for a title and we're generally in good shape," Rose told Sky. "Then we just give the game away in the first 10 minutes.

"The fact that you then get into problems with the ground and the strong opponent under the conditions is inexplicable and cannot be excused."

Dortmund had come into the DFB-Pokal game fresh from beating SC Freiburg 5-1 in the Bundesliga on Friday, as well as coming from behind to win 3-2 over Eintracht Frankfurt.

"It's a pity and a bit stupid of us that after a top performance against Freiburg and the game we played in Frankfurt, we didn't do it again," Rose said.

"Unfortunately, we are again confirming a few things that have been held up to us in the last few weeks, months and years. It's just our fault.

"The end pisses me off because it was a chance for a title and we're just giving the game away."

Erling Haaland's penalty was not enough to rescue Borussia Dortmund as they crashed out of the DFB-Pokal following a shock 2-1 defeat by St Pauli.

The reigning champions' title defence came to an abrupt end at Millerntor-Stadion, where the 2. Bundesliga leaders claimed a memorable victory.

Dortmund arrived in the tie having netted five goals without reply in their opening two matches of this season's DFB-Pokal, defeating Wehen Wiesbaden 3-0 and Ingolstadt 2-0.

Meanwhile, only Bayern Munich, Werder Bremen and Wolfsburg had beaten them in this competition since 2011.

However, they fell behind to Etienne Amenyido's fourth-minute strike, while an Axel Witsel own goal doubled the hosts' lead before the break.

Haaland halved the deficit from the penalty spot 13 minutes into the second half but ,despite eight shots on goal and 70.4 per cent of the possession, the visitors were unable to avert a shock exit.