Football has been a part of Peyton Manning's life since the day he was born, and his Pro Football Hall of Fame induction speech Sunday amounted to a love letter to the sport. 

The former Indianapolis Colts and Denver Broncos quarterback was the headliner at the ceremony in Canton, Ohio, that honoured the 2020 and 2021 inductees. 

Famously personable, Manning took amiable shots at former rivals like Tom Brady and thanked those who helped him reach the game's pinnacle – starting with his father, Archie – but spent a significant portion of his speech looking ahead. 

"We have inherited the history of this sport, even helped create it, but our responsibility cannot stop there," Manning said. "If we simply relive history and don't ignite the future of the sport, then we're not doing football justice."

Manning acknowledged threats to his sport's hegemony in the United States and its worldwide appeal, from an increasingly fractured entertainment market to concussion concerns and polarising social-justice issues, before vowing to do what he could to maintain the sport's prominence and encouraging others to do the same. 

"I don't know about you but I'm not done with this game. I never will be," he said. "I'm committed to ensuring its future, and I hope you will join me in that commitment.

"As members of this honoured class, we have a responsibility to make our game stronger, from the corner playground to the most-celebrated stadiums. ...

"When we leave this stage tonight, it is no longer about us. It is about cultivating the game that has given so much to us. It's about nurturing football to live and thrive another day, another year, decade and another generation."

Joining Manning in the Class of 2021 were receivers Calvin Johnson and Drew Pearson, defensive back Charles Woodson, safety John Lynch, guard Alan Faneca, pioneering coach Tom Flores and legendary scout Bill Nunn.

The Class of 2020, whose induction was delayed due to the coronavirus pandemic, included receivers Isaac Bruce and Harold Carmichael, safeties Steve Atwater and Troy Polamalu, defensive backs Bobby Dillon and Donnie Shell, tackles Jim Covert and Winston Hill, defensive tackles Alex Karras and Duke Slater, ends Mac Speedie and Ed Sprinkle, running back Edgerrin James, guard Steve Hutchinson, coaches Bill Cowher and Jimmy Johnson, general manager George Young, NFL Films co-founder Steve Sabol, and former commissioner Paul Tagliabue. 

Xavien Howard will be staying with the Miami Dolphins after the two parties agreed to a restructure of his contract.

The All-Pro cornerback last month requested a trade, saying he did not feel "valued or respected" by the team.

The 28-year-old signed a five-year, $76.5million extension in 2019, which at the time made him the highest-paid corner in the NFL.

However, Howard was seemingly irritated by not even being the highest-paid corner on his team, with Byron Jones signed to a five-year $82.5m deal to lure him from the Dallas Cowboys last year.

Jones' contract carries an average annual value of $16.5m compared to $15.05m for Howard.

Howard's 2021 base salary of $12m sees him paid over $2m less than Jones.

But the Dolphins have satiated the 2020 first-team All-Pro, who led the league in interceptions (10) last year, increasing his fully guaranteed money for this year to $12.78m and his maximum with added incentives to $16.28m.

Howard has also seen his 2022 base salary of $12.97m guaranteed against injury. It will become fully guaranteed on the first day of the 2022 league year. Additionally, it has been reported Howard has received assurances the Dolphins will revisit his deal next year should he stay healthy and perform at a productive level again in 2021.

On top of his league-leading interceptions tally, Howard recorded a career-high of 20 passes defended in 2020.

Per Stats Perform advanced data, Howard's adjusted open percentage – which measures how frequently an opponent got open against a defender's coverage, adjusted for position – was 25.19, almost a full percentage point better than that of Jones (26.16) in 2020.

His efforts last season helped the Dolphins lead the NFL in takeaways (29), though that did not translate to a playoff berth as Brian Flores' team finished 10-6.

The Dolphins have not reached the postseason since the 2016 campaign and have not won a playoff game since their Wild Card victory over the Indianapolis Colts in the 2000 season.

They begin their quest to end those droughts at the New England Patriots on September 12.

The Indianapolis Colts have made Darius Leonard the highest-paid inside linebacker in the NFL after signing him to a five-year contract extension worth $99.25million.

Leonard's deal includes $52.5m in guaranteed money, and he will receive an annual salary of $20m over the first three years, according to a report by NFL Media's Ian Rapoport.

It means he overtakes San Francisco 49ers star Fred Warner as the highest-paid player at the position.

Warner signed a five-year, $95m extension with the Niners last month, with his deal paying him $19m annually.

Leonard is one of the key players on a stout Colts defense that ranked 10th in yards per play allowed in 2020.

A second-round pick out of FCS program South Carolina State in 2018, Leonard was named Defensive Rookie of the Year after a stellar first season.

His 416 total tackles are the fourth-most among linebackers since 2018, while he ranks tied fifth for his position group with 22 pass breakups in that time.

Adept at stopping both the passing game and opposing rushing attacks, Leonard registered a run disruption rate of 9.1 per cent in 2020, putting him sixth among all linebackers, according to Stats Perform data.

The signing of Leonard to a long-term deal is some much-needed good news for the Colts, who have lost both quarterback Carson Wentz and All-Pro guard Quenton Nelson to foot injuries during training camp.

As a result, the pressure may be on Leonard and the defense to do the heavy lifting when the Colts start their 2021 campaign against the Seattle Seahawks on September 12.

Josh Allen has agreed a six-year contract extension with the Buffalo Bills reportedly worth $258million with $150m guaranteed.

The deal will keep Allen tied to the Bills through the 2028 season and will see him average an annual salary of $43m.

Buffalo traded up to select Allen with the seventh overall pick in the 2018 draft, making the bet that his outstanding athletic gifts would translate to NFL success despite concerns over his accuracy.

That looked a questionable move over the first two years of his career, despite a playoff appearance in the 2019 season.

However, Allen took a spectacular leap forward in 2020, leading the Bills on a run to the AFC Championship Game, where they lost to the Kansas City Chiefs.

Having failed to complete 60 per cent of his passes in 2018 or 2019, Allen posted a completion percentage of 69.2 in 2020, throwing for 4,544 yards, 37 touchdowns and 10 interceptions.

Allen's completion percentage, passing yardage and passing touchdowns all marked single-season records for the Bills. He also set franchise records for 300-yard games (8) and total touchdowns (46).

Per Stats Perform data, Allen was the seventh-best quarterback in the NFL when it came to delivering an accurate, well-thrown ball. He recorded a well-thrown percentage of 80.5 and was ninth in air yards per attempt among quarterbacks with at least 200 passes, averaging 8.92.

Yet the Bills were ultimately second-best to the Chiefs by a wide margin, losing 38-24 in the AFC title game. Buffalo start their campaign to go one better in 2021 with a Week 1 encounter against the Pittsburgh Steelers on September 12.

The Dallas Cowboys remain hopeful Dak Prescott will be ready for the season opener despite a shoulder injury that knocked him out of training camp, but they got a look at their other quarterback options as they opened the NFL pre-season on Thursday. 

Garrett Gilbert and Cooper Rush turned in solid performances even though they were unable to lead a touchdown drive in a 16-3 loss to the Pittsburgh Steelers in the Hall of Fame Game in Canton, Ohio.

Gilbert got the start and completed nine of 13 attempts for 104 yards and a 93.1 passer rating, while Rush came on in the second quarter and was eight-of-13 for 70 yards and a 75.8 rating.

Gilbert twice drove the Cowboys into the red zone but Dallas was left to settle for two field-goal tries, with Hunter Niswander making only one of them.

Niswander missed another field goal at the end of the first half, this one a 52-yarder, and Rush saw another of his drives end in a lost fumble by Malik Turner.

Despite those miscues, Dallas out-gained Pittsburgh 217-123 in the first half while racking up 13 first downs to Pittsburgh's six.

"The performance was decent," Gilbert told reporters. "We did some good things.

"Personally, I was a little sloppy with a couple of things, but it was good to knock the rust off. As an offense, we did a nice job overall of getting the ball moving."

Head coach Mike McCarthy concurred, saying he was pleased with the way his offence moved the football, but called for better finishing in the red zone.

They can expect that aspect to improve under Prescott, who did not travel to Canton for the game.

He told Fox Sports from California during the half-time show that he remains optimistic about being able to start the September 9 season opener against the Tampa Bay Buccaneers.

"We're being cautious," Prescott said. "We're taking it day by day, obviously. It's five weeks before the season opener, so I've got a lot of time. And I'm going to use that time to get myself ready for that game."

Nick Foles made it clear he has not had any talks with Frank Reich about a trade to the Indianapolis Colts, but he sounded distinctly like a man making his pitch for such a move on Monday.

The Colts are in a perilous situation at quarterback after Reich confirmed Carson Wentz, whom they traded for in the offseason to be their starter, would undergo foot surgery and miss five to 12 weeks.

Wentz is therefore in danger of missing the opening two months of the 2021 season, leaving the Colts facing up to the prospect of starting Jacob Eason, a fourth-round pick in the 2020 draft, under center.

Reich was the Philadelphia Eagles offensive coordinator when Wentz was in the MVP conversation in 2017 before he suffered a season-ending injury and was replaced by Foles, who spectacularly guided the Eagles to Super Bowl glory.

It was hoped the reunion between Reich and Wentz could revive the latter's career after his dismal final season with the Eagles but his injury has led to talk of the Colts bringing Foles, now the third-string quarterback with the Chicago Bears, into the mix.

Asked about that possibility, Foles told a media conference: "Frank Reich is one of my favourite if not favourite coaches of all time, he understands me as a player, he understands me as a person.

"I haven't had any talks with him. I'm a Chicago Bear right now. You all watched the 2017 season in the playoffs where he changed the offense and built it around me and y'all saw what happened, he understood my mentality as a player and he was able to build it around me and put me in a successful position.

"That being said they have Carson, and Carson and I have a lot of history. I have a lot of respect for Carson, he's a tremendous player, he's going through adversity once again but he'll bounce back. He might miss a few games but I know he'll be back out there, but we haven't had any talks.

"Right now I'm a Chicago Bear and I'm going to keep slinging it with these third-stringers and we're going to dice 'em up."

On talks with other teams, Foles added: "There was a couple of opportunities that came to me this offseason with a couple of teams but it wasn't the right time.

"It wasn't the right time or the situation with what was going on in my life. You don't just want to go somewhere to go somewhere, you want to go somewhere where you know the people somewhat or you know someone who knows the people that can vouch for the people so you can succeed.

"Listen, I feel great. The version of me right now is much better than the version of me that played in the Super Bowl, I'll tell you that and I'm confident in that, so put that through your mind, I know that.

"I know what this game's about, you have to have the whole package as a team, you have to have everyone in there. Top-down has to be great, if it's not great you're going to be mediocre. I've seen it and I've been a part of it, and unfortunately when you're a quarterback you've got to go through a lot of the baloney.

"That's part of it, that's why we play this position because at the end of the day there might be some kid that's watching this press conference and they say Nick Foles is a three quarterback and he's going out there and his mentality is to dice up that defense and help his team-mates and that's what I will continue to do until I lace up the cleats for the last time."

Indianapolis Colts quarterback Carson Wentz is to undergo foot surgery and could be out for as long as 12 weeks.

Colts head coach Frank Reich confirmed Wentz would have an operation on his left foot after injuring it during last Thursday's training camp practice and will need five to 12 weeks to recover.

Reich told reporters the injury was to Wentz's metatarsal and that the pain stemmed from a previous issue that could date as far back as high school.

The Colts traded for Wentz back in March, sending a 2021 third-round pick and a 2022 second-round pick that could become a first-rounder to the Philadelphia Eagles to land the 2016 second overall pick.

Philadelphia will receive a 2022 first-rounder if Wentz plays 75 per cent of the offensive snaps in 2021, or if he plays 70 per cent and the Colts make the playoffs.

However, the prospects of either scenario coming to pass now look slim, with the Colts' hopes of Reich getting Wentz's career back on track dealt a significant blow. 

"Obviously we're optimistic and hopeful that we can be on the front end of that [five to 12 week recovery time]," said Reich.

While Wentz is sidelined, the focus will be on getting Jacob Eason, a fourth-round pick in 2020, ready to start Week 1 against the Seattle Seahawks.

"The job is Jacob's right now … and he's gotta earn it," Reich added. "But he's in the driver’s seat."

Reich was the offensive coordinator in 2017 when Wentz was a frontrunner for the MVP award before a knee injury curtailed his campaign and backup Nick Foles improbably led the Eagles to their first Super Bowl title.

The Colts banked on a reunion with Reich helping Wentz rediscover that form following a 2020 season in which he suffered 50 sacks - the most of any quarterback in the league - and was tied-first for interceptions with 15.

As per Stats Perform data, Wentz had the worst well-thrown percentage in the NFL last year. He delivered an accurate, well-thrown ball on just 68.8 per cent of his passes. He threw a pickable pass on 6.78 per cent of his attempts, with only three quarterbacks doing so more often.

The Colts will now have to wait to see if he can bounce back and reprise his 2017 form, while Eason has the opportunity to give Reich a headache in the game's most important position.

The Cleveland Browns have officially announced running back Nick Chubb's contract extension, a move that sees them lock down a player who has quickly established himself as one of the best at his position.

Chubb's three-year extension with the Browns was initially reported on Sunday. It is said to be a deal worth $36million, of which $20m is guaranteed.

It is just reward for Chubb's incredible start to his NFL career, which has seen him rack up the third-most rushing yards in the league since being drafted in 2018. He has 3,557 yards in his career, a tally bettered by only Derrick Henry (4,620) and Ezekiel Elliott (3,770), as well as 28 rushing touchdowns in that time.

Baltimore Ravens quarterback Lamar Jackson (6.03) is the only player to have posted a better rushing average than Chubb's 5.23 yards per carry across the last three seasons.

A key reason for Chubb's success has been his ability to stay on his feet through tackle attempts. He has finished in the top five in broken tackles in each of his three NFL seasons and was tied for first with Dalvin Cook last season with 14.

Chubb was third in yards after contact per rushing attempt in both 2019 (2.37) and 2020 (2.59) and Browns executive vice president of football operations and general manager Andrew Berry is excited at the prospect of him leading Cleveland's backfield in the coming seasons.

"From the day Nick Chubb first entered our facilities, it was clear to see that he would become a pillar of our organisation," said Berry.

"Although Nick may be a man of few words whose strong-and-silent demeanour can be easy to overlook from the outside, his actions over the past three years have reverberated within the walls of our building.

"Nick's on-field contributions stand for themselves. He is a dynamic runner who is on pace to be one of the most accomplished players to ever don an orange helmet at the position.

"But it's his work ethic, intelligence, toughness and selflessness that makes us proud that he represents our city.

"Quite plainly, Nick embodies the soul of our team and we are thrilled that he will be a Cleveland Brown for years to come."

Minnesota Vikings head coach Mike Zimmer expressed his disappointment and frustration with unvaccinated players Saturday after three of his team's four quarterbacks missed practice due to COVID-19 protocols. 

Starting quarterback Kirk Cousins and backups Kellen Mond and Nate Stanley had to sit out the evening workout, leaving Jake Browning to take all of the reps under center. Offensive lineman Wyatt Davis, who played center Friday, also missed Saturday's practice. 

The Vikings released a statement prior to the workout that read: "Due to the NFL-NFLPA COVID-19 protocols, multiple players will be held out of tonight's practice inside TCO Stadium."

Zimmer met with reporters before the workout and did not address the missing quarterbacks by name. 

He did, however, make a plea to his players and everyone else. 

"It’s why people should get vaccinated,’’ Zimmer said. "[If] something like this happens a day before a game that has a chance to get you to the playoffs or something like that, [it could hamper a team].

"This Delta variant is rough. You can see the cases going up every single day now. That’s why, for the sake of everybody’s health, I think it’s important. But some people don’t understand, I guess.

"I am disappointed that this happened. I’m frustrated with, not just with my football players who won’t get vaccinated, I’m frustrated with everybody [who won’t]."

It was not clear when the players who sat out Saturday's practice would be able to return. 

In the meantime, Browning will be the star of the show for the Vikings.

"Jake’s really smart," Zimmer said. "He’s vaccinated. That helps to be the backup. So as we move forward here, he’s going to get a ton of reps.

"I don’t know about saying 'it’s going to go a long way' because we’ve still a lot of camp to go. But we’ll see.

"He’s out there, he’s available, that’s important. It’s important to be available when you’re playing football, a team sport."

Indianapolis Colts quarterback Carson Wentz is undergoing further tests on a foot injury that has ruled him out of participating in practice.

Wentz, who arrived at the Colts via a trade with the Philadelphia Eagles during the offseason, sustained the injury late during Thursday's session, according to reports.

The 28-year-old has endured several injury problems since making his NFL debut with the Eagles, who drafted him second overall in 2016.

Indeed, he has started all 16 games in a season just twice in his career, while inconsistent form last term saw him benched in favour of rookie Jalen Hurts.

Wentz also missed the Eagles' triumph over the New England Patriots at Super Bowl LII with a torn ACL, left to watch on as back-up Nick Foles led the franchise to glory.

Offensive coordinator Marcus Brady told the media that the Colts are still assessing the extent of the damage.

"He's with the docs, trying to figure what out the process is," he said of Wentz.

"(We are) still evaluating what the next move is, how bad it is. Then we'll go from there."

The Colts, who reached the playoffs last season, step up their preparations for the 2021 campaign next month with pre-season games against the Carolina Panthers, Minnesota Vikings and Detroit Lions.

They begin the regular season at home against the Seattle Seahawks on September 12.

After missing the first two practices of camp, second overall draft pick Zach Wilson came to an agreement with the New York Jets on his rookie contract on Thursday.

Wilson, the last of the first rounders to sign, received a fully guaranteed contract that will pay him $35.15million over four years. The deal includes a fifth-year team option and a $22.9m signing bonus.

The sides had reportedly been hung up on the contract’s offset language, which protects the team financially if the player is cut before the end of the deal.

Wilson is assumed to be the Jets’ Week One starting quarterback after the club moved on from Sam Darnold during the offseason and invested the franchise’s highest draft pick since 1996 in the 21-year-old quarterback.

About 30 minutes before the deal was made public, new head coach Robert Saleh indicated he was not worried about Wilson missing the first two camp practices.

“You're not going to see me panic,” he said after practice on Thursday. “Like I've said, there are 89 guys that are counting on us to prepare them the best way we know how. And right now, they've got our full attention.

“Zach's going to sign. And when it happens is when it happens. I don't try to worry about things I have no control over. So when it gets done, it'll be awesome to get him back.”

Wilson participated in the team’s minicamp and offseason activities, making some impressive throws but also showing some expected signs of his inexperience.

While adjusting to the speed and complexity of the pro game, Wilson will also be forced to adapt to the bright lights of Broadway after growing up in Utah and playing his college football at Brigham Young University.

Wilson played 30 games in three seasons at BYU but made a leap in his junior season, completing 73.1 percent of his passes and piling up 32 touchdowns to just three interceptions while adding 10 scores on the ground.

Saleh said he last spoke to Wilson earlier this week and added that offensive coordinator Mike LaFleur has been texting the quarterback about the playbook to keep him from falling behind.

“We'll be excited when he gets here,” Saleh said with a smile. “And it'll be good to not have to answer questions about it.”

New Orleans Saints head coach Sean Payton did not attempt to hide his frustration with Michael Thomas' absence from the start of training camp. 

The Saints' star wide receiver had surgery last month to repair an ankle injury that limited him throughout the 2020 season. 

General manager Mickey Loomis told reporters at a pre-camp news conference that the decision was taken to treat Thomas' injury "conservatively" in hopes that it would heal with treatment. 

Thomas participated in last month's minicamp, but the team decided afterward he needed to have surgery to return to 100 per cent. 

"It's disappointing. We'll work through it with the other players that are here," Payton said Wednesday.

"But the surgery took place, and obviously we would have liked that to have happened earlier than later. And quite honestly, it should have."

He declined to elaborate further on the timing of the procedure. 

Earlier, Loomis spoke about the team's thinking around Thomas' injury throughout the off-season. 

"We had an expectation that that would heal and he'd be fine coming into camp this year, but we get to minicamp and obviously it wasn't quite right," he said. 

"Obviously, with hindsight, we would have preferred that surgery to be earlier, in February or March, but it wasn't. It is what it is. And hopefully we'll get him back sooner rather than later."

Loomis declined to put a timeline on Thomas' potential return, and Payton indicated the team will not look for outside help during his absence. 

Thomas, 28, was the NFL's Offensive Player of the Year in 2019 after making a record 149 receptions for a league-leading 1,725 yards and nine touchdowns. 

His 2020 playing time was limited by the ankle injury he suffered in last season's opening game, as he wound up appearing in just seven regular-season games and making 40 catches for 438 yards. 

Days into preseason camp, the Dallas Cowboys already have reason for concern after quarterback Dak Prescott left practice early Wednesday with a shoulder injury. 

Prescott walked off the field at Cowboys camp in Oxnard, California after experiencing soreness in his right arm. 

The team said later that an MRI exam revealed a muscle strain in his right shoulder and will be "evaluated on a day-to-day basis." 

Wednesday was to be Prescott's first practice with the team in full pads since his 2020 season ended in Week 5 with a fracture-dislocation of his right ankle. 

Prescott, who turns 28 on Thursday, downplayed any concerns in a statement released by the team. 

"I felt some soreness when making certain throws today, and I really just decided not to push things too far," he said. "Better to be cautious and smart about it.

"I don't see this as any kind of serious setback. We'll treat it on a daily basis, and I'll be fine." 

Prescott is entering his sixth season as the Cowboys' quarterback. In 2019, his last full campaign, his career-best 4,902 passing yards were second in the NFL to Jameis Winston (5,109), and his 30 touchdown passes ranked fourth in the league. 

Garrett Gilbert ran the first-team offence in Prescott's absence for the rest of Wednesday's practice. 

The Cowboys have one more preseason game than most teams, the August 5 Hall of Fame Game against the Pittsburgh Steelers in Canton, Ohio, but Prescott was not expected to play in that contest anyway. 

Dallas will open the regular season September 9 away to Tom Brady and the Super Bowl champion Tampa Bay Buccaneers. 

Aaron Rodgers considered retirement during his stand-off with the Green Bay Packers but said the "fire still burns" to play in the NFL.

Rodgers reported to training camp on Tuesday and was on the field for practice on Wednesday having brought his self-imposed exile to a close.

A report before the start of the first round of the 2021 NFL Draft in April revealed Rodgers had informed some within the Packers organisation of his desire not to return to the team.

However, the two sides found common ground and came to an agreement to ensure Rodgers will play for the Packers in 2021.

Speaking at a media conference, Rodgers revealed the saga stretched back to conversations he had with the franchise in February following the Packers' second successive NFC Championship Game loss in which he stated his desire to be involved in conversations about playing personnel.

There had been talk of Rodgers calling time on his NFL career and the reigning league MVP revealed that thought had crossed his mind.

Rodgers said: "It's [retirement] definitely something I thought about. I talked about how important being a full-timer was for a long time, this was the first time to spend the offseason away without a Covid year or a lockout year, and I enjoyed it, I really did.

"I took time working on myself and trying to better myself in a number of areas where I feel like I can improve based on my own patterns and conditioning and it was a lot of growth in that process by continuing to find joy and happiness in things off the field.

"However, there's still a big competitive hole in my body that I need to fill and, as I got back into my workouts, I just realised that I know I can still play and I want to still play and as long as I feel like I can give 100 per cent to the team then I should still play.

"I was really working on myself and my own mental state throughout the summer and at various points deciding if I wanted to even keep playing but the fire still burns and I wanted to be on a football team and we got some things figured out in the last few days and I'm here."

One move the Packers have made to seemingly satiate Rodgers is to bring back receiver Randall Cobb in a trade with the Houston Texans. Rodgers spoke of his excitement at the return of Cobb, who racked up 5,524 receiving yards and 41 touchdowns in eight seasons with Green Bay between 2011 and 2018.

And on a reported "list of concessions" made by Green Bay is the Packers' agreement "to review Rodgers' situation at the end of this season".

ESPN's Adam Schefter reported "the biggest concession" was "the freedom to decide where he wants to play in 2022".

But Rodgers said it is not his understanding he can choose where he wants to play next offseason and refused to make any declarative statements about being with the Packers past 2021.

He added: "I'm just going to focus on this year, there's a lot of moving pieces besides myself, expiring contracts for a number of guys, there's going to be a lot of tough decisions at the end of the year.

"I'm just going to enjoy this year and then revisit that conversation at the end of the season."

On the possibility of finishing his Hall of Fame career with the Packers, Rodgers said: "I'm definitely not closing the door on anything. I'm always optimistic in the ability to change. I'd never want anyone to give up on me."

Lamar Jackson has tested positive for coronavirus, disrupting the Baltimore Ravens' preparations for the new NFL season.

Ravens coach John Harbaugh revealed on Wednesday his quarterback was missing the team's first practice of training camp.

Former NFL MVP Jackson reported to camp last Thursday but only returned a positive result on Tuesday, with running back Gus Edwards also confirmed as a case.

Harbaugh, who would not reveal how long the pair would be sidelined for, said: "It's just part of the deal. It's just the way the world is right now.

"It's no different than if somebody gets an injury – you tweak an ankle and you're out for some number of days. It's just part of football.

"To me, whenever you have a problem or whenever something comes up like that, you embrace it and you almost kind of rejoice in it because it's an opportunity to improve somewhere else."

Trace McSorley and Tyler Huntley took the majority of snaps in Wednesday's practice, with Robert Griffin III waived by Baltimore in January.

Griffin started for the Ravens on both occasions Jackson was missing over the past two seasons, including when he previously tested positive for COVID-19 ahead of the Week 12 trip to the Pittsburgh Steelers in 2020.

In a 19-14 defeat, Griffin completed seven of 12 passes for 33 yards and an interception.

McSorley came off the bench to supply their sole touchdown pass, connecting with Marquise Brown for a 70-yard score from one of only two successful throws.

Across the other 15 games, Jackson regressed from his MVP year, his passer rating falling from 113.3 to 99.3 as 36 touchdowns and six interceptions became 26 TDs and nine picks.

He still passed 1,000 rushing yards, however, and scored seven times with the ball in his hands.

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