The only thing to be sure about with the Champions League, is that nothing's for sure.

That is at least what Liverpool fans will be telling themselves as Jurgen Klopp's men prepare to try to overturn a three-goal first-leg deficit against Real Madrid at the Santiago Bernabeu on Wednesday.

Carlo Ancelotti continued his habit of terrorising Liverpool as his team staged a comeback of their own, recovering from 2-0 down at Anfield to run out 5-2 winners.

The LaLiga giants also defeated the Reds in last season's Champions League final, and so the hunger for revenge should be strong, but to come back against a team as strong as Madrid seems fanciful... or so it would seem.

Perhaps the most famous comeback in the competition's history is Liverpool breaking Ancelotti's heart in the final in Istanbul in 2005 as they turned around a three-goal margin in six second-half minutes before beating Milan on penalties, and Stats Perform has taken a look at some of the most notable second-leg Champions League comebacks of all-time to see if there is any cause for optimism for Klopp's team.

Deportivo La Coruna v Milan – Quarter-finals, 2003-04

Speaking of Ancelotti's Milan, they had a strange relationship with the Champions League over a three-year period between the 2002-03 season and that famous night in Istanbul 18 years ago.

The Rossoneri won the 2003 final against Juventus on penalties after an astonishingly dull 120 minutes at Old Trafford, before their agonising defeat to Liverpool at the same stage two years later.

What happened in between might have been the most bizarre of the lot, though.

In the last eight of the 2003-04 season, Milan eased to a 4-1 win against Spanish side Deportivo La Coruna in the first leg at San Siro.

It would turn out to be a strange season for the competition overall, with upsets all over the place, but none as remarkable as Deportivo's turnaround in the second leg at the Riazor Stadium.

Three goals in the first half from Walter Pandiani, Juan Carlos Valeron and Albert Luque put them ahead on away goals, before substitute Gonzalo Fran sealed a sensational 4-0 win in the second half to take the tie 5-4 on aggregate.

Barcelona v Paris Saint-Germain – Last 16, 2016-17

The biggest and arguably most famous comeback in Champions League history, Barcelona looked dead and buried after a 4-0 trouncing at the hands of PSG at the Parc des Princes in the first leg.

Goals from Angel Di Maria (two), Julian Draxler and Edinson Cavani looked to have put the tie to bed before the second leg at Camp Nou had even begun.

Luis Suarez scored just three minutes in to provide hope, while a Layvin Kurzawa own goal just before half-time was followed by a penalty from Lionel Messi just after as the impossible suddenly looked possible.

Cavani scored what seemed to be a crucial away goal for PSG just after the hour though as hopes began to fade for the Catalans.

In the closing stages, head coach Luis Enrique raised eyebrows when he turned to Sergi Roberto from the bench, hardly known for his goalscoring exploits at a time when they needed three in a short period.

Neymar made it 4-1 on the night in the 88th minute with what most assumed was just a consolation, before Barca were given a penalty soon after, which the Brazilian also dispatched.

With seconds remaining deep into stoppage time, Neymar lofted a ball into the box to find Sergi Roberto, who applied the finish and sealed an unbelievable 6-5 aggregate win.

 

Roma v Barcelona – Quarter-final, 2017-18

Of course, what goes around, comes around and Barca were on the wrong end of a dramatic turnaround just a year later.

Their 4-1 home win in the first leg had them full of confidence heading to the Italian capital for the second.

As with Barca's comeback against PSG, the return encounter started with an early goal, with Edin Dzeko finding the net just six minutes in at the Stadio Olimpico.

The Blaugrana held out until half-time without further damage, but Daniele De Rossi scored a penalty to bring Roma to within one goal of going through on away goals.

With eight minutes remaining, Kostas Manolas headed in a corner at the near post to send the home fans into absolute delirium and improbably take the Serie A side through.

It was a chastening experience for Barca, but surely it was just a one-off...

Liverpool v Barcelona – Semi-final, 2018-19

After a 3-0 win against the Premier League challengers at home, Barca had put themselves in a strong position again, but this time with the caution that was necessary after their humbling by Roma.

Yet again, an early goal gave hope to the optimists as Divock Origi bundled in the opener for Liverpool in the seventh minute, but yet again, Barca held out until the break, knowing Liverpool still needed two just to take it to extra-time.

Those two arrived in very quick succession as half-time substitute Giorginio Wijnaldum made it 2-0 in the 54th minute with a sweeping finish before heading in a third less than two minutes later.

All the momentum was with Liverpool, and with an almost inevitable amount of farce, a quickly-taken corner by Trent Alexander-Arnold caught the visitors napping as Origi slammed in a fourth.

Two seasons in a row, Barca had thrown away three-goal leads from the first leg, amounting for half of the four occasions it has happened in the competition's history.

 

Manchester United v Paris Saint-Germain – Last 16, 2018-19

While this was not a comeback from a three-goal deficit, it is the only example of a tie in which the team that has played the second leg away from home has won despite losing the first leg by more than one goal.

PSG outclassed United at Old Trafford, winning 2-0 thanks to goals from Presnel Kimpembe and Kylian Mbappe, while Paul Pogba was sent off late on for the hosts.

The dominant nature of the win more than anything else is why few gave United a hope of turning things around in Paris, but once more, an early goal changed the mood as Romelu Lukaku scored in the Parc des Princes with less than two minutes played.

Juan Bernat equalised soon after, but Lukaku restored United's lead on the half-hour mark.

PSG tried to put their English opponents away but in stoppage time, conceded a penalty for handball against Kimpembe, allowing Marcus Rashford to fire home to give the Red Devils a place in the history books.

So where does this leave Liverpool's chances of overcoming a three-goal deficit in Madrid?

Well, Los Blancos have only lost at home by a three-goal margin twice in the Champions League, both in the 2018-19 campaign, going down 3-0 to CSKA Moscow in the group stage and 4-1 against Ajax in the last-16 second leg.

Meanwhile, Liverpool have won an away game in the Champions League by three or more goals on 10 occasions, eight of which have come under Klopp, while they only very recently beat Manchester United 7-0 in the Premier League, albeit that was at Anfield and was swiftly followed by a limp 1-0 defeat at Bournemouth on Saturday.

You could argue that if it were any other team than Madrid, who seem to have a spell over the famous tournament, you would give Liverpool a chance of doing it such is their own record of dramatic appearances in the Champions League.

It seems like an impossible task, but you could also argue that if ever there were an opponent who could do such a thing to Madrid, it may be the Reds, especially given their past with Ancelotti.

It would certainly raise an eyebrow.

Sensational comebacks are increasingly a staple of the modern Champions League, and this season they have belonged almost exclusively to Real Madrid.

Los Blancos trailed Manchester City 1-0 heading into the 90th minute at the Santiago Bernabeu on Wednesday, with Pep Guardiola's team leading 5-3 on aggregate.

Yet two goals in the space of 91 seconds from Rodrygo forced extra-time, and Carlo Ancelotti's team set up a meeting with Liverpool in Paris when Karim Benzema converted a penalty to claim a 3-1 win (6-5 on aggregate).

It was the third stunning turnaround Madrid have enjoyed in the knockout stages this campaign, following Benzema's hat-trick against Paris Saint-Germain in the last 16 and Rodrygo's goal against Chelsea to secure an aggregate win in the quarters last month.

Here's a few other incredible comebacks to jog your memory.

Real Madrid 3-1 PSG (3-2 agg), 2022

Madrid have done it the hard way this season, as they target a 14th European title. 

Not many fancied them to get through against PSG, especially when Kylian Mbappe, who had scored a stunning goal in the first leg in Paris in February, put Mauricio Pochettino's team ahead at the Santiago Bernabeu with a crisp finish.

Yet Gianluigi Donnarumma's slack play enabled Benzema to pounce and pull one back, with the striker then scoring twice in two minutes to turn the tie on its head and set Madrid en route to the final.

Barcelona 6-1 PSG (6-5 agg), 2017

Barcelona remain the perpetrators of the most remarkable of all Champions League comebacks, at least in terms of deficit overhauled.

Trailing 4-0 from the first leg of their last-16 tie with PSG, Luis Suarez and Lionel Messi scored either side of a Layvin Kurzawa own goal, only for Edinson Cavani to grab what was expected to be the decisive strike for the visitors.

However, two quick Neymar goals – the second a highly controversial penalty after an apparent Suarez dive – levelled the tie at 5-5.

Then, in the fifth minute of stoppage time, Sergi Roberto struck to create a slice of Champions League history – no side had ever turned around a four-goal first-leg deficit before.

Roma 3-0 Barcelona (4-4 agg, Roma won on away goals), 2018

The boot was on the other foot when Barcelona were dethroned in the Italian capital last year as Roma completed one of the most unlikely turnarounds in quarter-final history.

Eusebio Di Francesco's side came back from a 4-1 first-leg deficit to progress to the last eight on away goals after a thrilling 3-0 win in front of their home fans.

Edin Dzeko, Daniele De Rossi and Kostas Manolas secured the 4-4 aggregate draw and sent the Stadio Olimpico into raptures, as Barca completely fell to pieces.

Liverpool 4 Barcelona 0 (4-3 agg), 2019

Fresh from netting a late winner at Newcastle United the weekend before, Divock Origi allowed the Liverpool faithful to dream by poaching his maiden Champions League goal in the seventh minute.

Jurgen Klopp needed Alisson to be on form as he saved from Messi and Suarez, before another unlikely hero emerged.

Andrew Robertson's injury forced James Milner to left-back and Georginio Wijnaldum into the fray at half-time. By the hour, the Dutch midfielder had Liverpool level thanks to two goals in 122 delirious seconds.

Origi had the final word thanks to Trent Alexander-Arnold's quick thinking from a 79th-minute corner, leaving Barcelona and Messi crestfallen once more. The Reds went on to beat Tottenham in an all-English final.

Real Madrid 1-4 Ajax (5-3 agg), 2019

Despite their impressive display in their 2-1 first-leg defeat, nobody really seemed to think Ajax could turn things around at the Santiago Bernabeu. Sergio Ramos certainly did not – he earned a booking to avoid the risk of a quarter-final ban, earning an extra-game suspension from UEFA in the process.

In the absence of their captain, Madrid completely capitulated amid a fearless and thrilling Ajax – the type of which Liverpool might yet be faced with in the final.

Hakim Ziyech and David Neres put the visitors 2-0 up after only 18 minutes and it was 3-0 just after the hour mark thanks to the inspired Dusan Tadic.

Marco Asensio got a goal back, but Lasse Schone's free-kick beat Thibaut Courtois and sent Madrid crashing out. It was the first time they had ever been knocked out after winning the first leg of a Champions League tie.

PSG 1-3 Manchester United (3-3 agg, United won on away goals), 2019

It really had been quite the season for upsets in Europe's premier competition. A day on from Ajax's thrashing of Madrid, United made history at Parc des Princes.

No side had ever won a knockout tie after trailing 2-0 from a first leg at home, and with 10 senior players missing, including the banned Paul Pogba, United's chances looked slim.

Romelu Lukaku scored just two minutes in, though, and despite Juan Bernat's equaliser on the night, Lukaku struck again after a Gianluigi Buffon error to make it 2-1.

As the game crept towards second-half injury time, Diogo Dalot's shot struck Presnel Kimpembe's arm and the referee awarded a penalty after a lengthy VAR review. Marcus Rashford scored it, United progressed, and the clamour for Solskjaer to be given the permanent manager's job grew louder.

Deportivo La Coruna 4-0 AC Milan (5-4 agg), 2004

Deportivo were among Spain's major forces just after the turn of the century and one of their finest moments in Europe came in April 2004 when, despite being 4-1 down from the first leg of their Champions League quarter-final with AC Milan, they stunned the Italians at home.

Walter Pandiani, Juan Carlos Valeron and Albert Luque had Depor ahead on away goals before half-time, with Fran Gonzalez – who played for them in the second division in the late 80s and is still their record appearance holder – fittingly scored the fourth to make sure of their passage.

Depor were eliminated by eventual winners Porto in the semi-finals, but this comeback stood as arguably the very best in Champions League history until Barca went one better.

Liverpool 3-3 AC Milan (AET, 3-2 on pens), 2005

That famous night in Istanbul. Liverpool found themselves on the end of a hiding at half-time in the 2005 Champions League final, as Paolo Maldini and a Hernan Crespo brace had the Serie A side 3-0 up.

But the second half proved to be one of the most iconic 45 minutes in Liverpool's history, with goals from Steven Gerrard, Vladimir Smicer and Xabi Alonso levelling the match up by the hour mark.

Milan then failed to hold their nerve in the penalty shootout, as Jerzy Dudek's leggy antics in the Liverpool goal helped the Pole outsmart both Andrea Pirlo and Andriy Shevchenko after Serginho blazed the first kick over, resulting in the Premier League side lifting their fifth European title.

Manchester United 2-1 Bayern Munich, 1999

Possibly the two most dramatic minutes in the history of European club football.

United were trailing 1-0 to Bayern Munich in the 1999 final at Camp Nou, with Mario Basler's skidding free-kick into the bottom-right corner looking set to be enough for the Bavarian giants to end a 23-year wait for glory in the continent's top-tier competition.

However, the United of Alex Ferguson's era could never be discounted until the final whistle, and substitute Teddy Sheringham swept Ryan Giggs' shot into the bottom corner to bring the scores level in the 91st minute.

Solskjaer, another late substitute and now the man in the United dug-out, avoided the need for extra time by stabbing Sheringham's header from a David Beckham corner into the roof of the net as United completed an historic treble in astonishing fashion.

Barcelona 5-1 Chelsea (AET, 6-4 agg), 2000

A 3-1 first-leg loss at Stamford Bridge – having trailed 3-0 – had Barca in danger of being on the wrong end of a major 1999-00 Champions League upset prior to the Roman Abramovich era, but in the return match the Catalans showed their true class.

Tore Andre Flo's 60th-minute goal was sending Chelsea through despite Rivaldo and Luis Figo scoring before the break, but Dani Garcia scored seven minutes from the end of regulation to force extra time.

Rivaldo then converted a penalty after Celestine Babayaro was sent off and Patrick Kluivert wrapped things up, crushing Chelsea's dreams.

Much has changed in European football in the past five years – and few clubs illustrate that greater than fallen giants Barcelona.

On this day in 2017, Barca were thrashing Paris Saint-Germain 6-1 in the most remarkable Champions League turnaround ever, becoming the only side in the competition's history to overturn a four-goal first-leg deficit.

Now, Neymar and Lionel Messi – the two stars of that Blaugrana side – are preparing to play Real Madrid as PSG players.

Meanwhile, Barca are not even in the Champions League knockout stages, instead facing Galatasaray in the Europa League last 16 while battling to return to UEFA's flagship competition next season.

Indeed, Barca's recent European past has found them on the wrong end of epic Champions League comebacks, but that PSG classic still ranks among the tournament's greatest two-legged recoveries – remembered by Stats Perform here...

2019: Liverpool 4-0 Barcelona (4-3 on aggregate)

One of a couple of examples Barca fans will not remember so fondly, Jurgen Klopp's Liverpool had been well beaten at Camp Nou, with the 3-0 scoreline flattering the Catalans but making them clear favourites to complete their semi-final task at Anfield.

Liverpool were without injured forwards Mohamed Salah and Roberto Firmino for the second leg, yet two goals each from Divock Origi and Georginio Wijnaldum saw the hosts defy the odds in sensational style.

Origi had the final word thanks to Trent Alexander-Arnold's quick thinking from a 79th-minute corner.

It meant a Barca side boasting Messi and former Liverpool stars Philippe Coutinho and Luis Suarez were left devastated, while Klopp's men celebrated reaching the final, where they would win a sixth title.

2019: Ajax 2-3 Tottenham (3-3 agg)

The night after Liverpool's win, Ajax looked certain to join the Reds in the final when they extended their 1-0 first-leg lead to 3-0 in Amsterdam with first-half goals from Matthijs de Ligt and Ziyech.

Mauricio Pochettino's Tottenham took inspiration from Liverpool's stunning fightback 24 hours earlier, though, and Lucas Moura stepped up to emerge as their hero.

The Brazilian forward scored an improbable hat-trick in the second half, the vital third goal coming deep into stoppage time, as Spurs won on away goals.

2018: Roma 3-0 Barcelona (4-4 agg)

Barcelona were stunned in the Italian capital as Roma completed one of the most unlikely quarter-final turnarounds – another that benefited from an away goals rule that has since been scrapped.

Eusebio Di Francesco's side came back from a 4-1 first-leg deficit to progress to the last four after a thrilling 3-0 win in front of their home fans.

Edin Dzeko, Daniele De Rossi and Kostas Manolas secured the 4-4 aggregate draw and sent the Stadio Olimpico into raptures, as Barca fell to pieces.

2017: Barcelona 6-1 Paris Saint-Germain (6-5 agg)

Those humblings at the hands of Roma and Liverpool make for painful memories for those of a Blaugrana persuasion, but this remains the ultimate 'Remontada'.

Trailing 4-0 from the first leg of their last-16 tie with PSG, Suarez and Messi scored either side of a Layvin Kurzawa own goal, only for Edinson Cavani to grab what was expected to be the decisive away goal for the visitors.

However, two quickfire Neymar goals – the second a highly controversial penalty after an apparent Suarez dive – brought it back to 5-5, meaning Barca needed just one more.

Then, in the fifth minute of stoppage time, Sergi Roberto struck from Neymar's cross to create Champions League history.

2004: Deportivo La Coruna 4-0 Milan (5-4 agg)

Deportivo were among Spain's major forces just after the turn of the century and one of their finest moments in Europe came in April 2004 when, despite being 4-1 down from the first leg of their Champions League quarter-final with Milan, they stunned the Rossoneri at the Riazor.

Walter Pandiani, Juan Carlos Valeron and Albert Luque had Depor ahead on away goals before half-time, with veteran Fran Gonzalez scoring the fourth to make sure of their passage.

Depor were eliminated by eventual winners Porto in the semi-finals, but this comeback stood as arguably the very best in Champions League history until Barca went one better.

2000: Barcelona 5-1 Chelsea (aet, 6-4 agg)

Barca already had a history of Champions League fightbacks.

A 3-1 first-leg loss at Stamford Bridge – having trailed 3-0 – had the Blaugrana in danger of being on the wrong end of a major Champions League upset prior to Chelsea's Roman Abramovich era, but in the return match the Catalan giants showed their true class.

Tore Andre Flo's 60th-minute goal was sending Chelsea through despite Rivaldo and Luis Figo scoring before the break, but Dani Garcia headed home seven minutes from the end of regulation to force extra time.

Rivaldo atoned for an earlier missed penalty by converting from the spot after Celestine Babayaro was sent off, and Patrick Kluivert finished the game off, crushing Chelsea's dreams.

Barcelona's Champions League campaign feels all but over as they head to Paris Saint-Germain nursing a 4-1 last-16 deficit.

Kylian Mbappe made merry at Camp Nou last month, netting a brilliant hat-trick after Lionel Messi gave the hosts a first-half lead.

The fact the defeat came on their own patch makes Barca's hopes even more remote, but they've been on both sides of incredible recent Champions League comebacks – most famously in this very fixture.

Here, we look at some of the nights in Europe's top competition where logic left town.

2019: Liverpool 4-0 Barcelona (4-3 on aggregate)

Jurgen Klopp's Liverpool had been well beaten at Camp Nou, with the 3-0 scoreline flattering Barcelona but making the Catalans clear favourites to complete their semi-final task on Merseyside.

Liverpool were without injured forwards Mohamed Salah and Roberto Firmino for the second leg, yet two goals each from Divock Origi and Georginio Wijnaldum saw the hosts defy the odds in sensational style.

They were Origi's first goals in the competition, while only 122 seconds separated Wijnaldum's pair in a pivotal period that left Anfield rocking.

Origi had the final word thanks to Trent Alexander-Arnold's quick thinking from a 79th-minute corner.

It meant a Barcelona side boasting Messi – who was involved in all of Barca's eight attempts on goal with five shots and three key passes - and former Liverpool stars Philippe Coutinho and Luis Suarez were left devastated, while Klopp's men celebrated reaching the Madrid final.

2019: Real Madrid 1-4 Ajax (5-3 on aggregate)

Despite an impressive display in their 2-1 first-leg defeat, few thought Ajax could turn things around at the Santiago Bernabeu. Madrid's Sergio Ramos certainly did not - he earned a first-leg booking to avoid the risk of a quarter-final ban, receiving an extra-game suspension from UEFA in the process.

In the absence of their captain, Madrid capitulated against a fearless and thrilling Ajax. Hakim Ziyech and David Neres put the visitors 2-0 up after only 18 minutes and it was 3-0 just after the hour thanks to the inspired Dusan Tadic.

Marco Asensio got a goal back, but Lasse Schone's free-kick beat Thibaut Courtois and sent Madrid crashing out on the back of their heaviest margin of defeat in a European knockout game. It was the first time Madrid had ever been knocked out after winning the first leg of a Champions League tie, while Ajax would themselves be stung by a comeback in the semi-finals.

2019: Ajax 2-3 Tottenham (3-3 agg)

Ajax looked certain finalists when they extended their 1-0 first-leg lead to 3-0 on aggregate in Amsterdam, thanks to first-half goals from Matthijs de Ligt and Ziyech.

Mauricio Pochettino's Spurs took inspiration from Liverpool's stunning fightback against Barcelona 24 hours earlier, though, and Lucas Moura stepped up to emerge as their hero.

The Brazilian winger was thrust into a central attacking role and scored an improbable hat-trick – just the fifth time the feat had been accomplished in a Champions League semi-final - in the second half, the vital third goal coming deep into stoppage time, as Spurs won on away goals.

2018: Roma 3-0 Barcelona (4-4 agg)

Barcelona were stunned in the Italian capital as Roma completed one of the most unlikely quarter-final turnarounds.

Eusebio Di Francesco's side came back from a 4-1 first-leg deficit to progress to the last four on away goals after a thrilling 3-0 win in front of their home fans.

Edin Dzeko, Daniele De Rossi and Kostas Manolas secured the 4-4 aggregate draw and sent the Stadio Olimpico into raptures, as Barca fell to pieces.

2017: Barcelona 6-1 Paris Saint-Germain (6-5 agg)

Before being humbled by Roma and Liverpool, Barcelona pulled off an astonishing Champions League comeback of their own - the greatest so far in terms of the deficit overhauled and one that PSG fans will still shudder to be reminded of this week

Trailing 4-0 from the first leg of their last-16 tie with PSG, Suarez and Messi scored either side of a Layvin Kurzawa own goal, only for Edinson Cavani to grab what was expected to be the decisive away goal for the visitors.

However, two quickfire Neymar goals against his future club – the second a highly controversial penalty after Suarez took a tumble – levelled the tie at 5-5.

Then, in the fifth minute of stoppage time, Sergi Roberto struck to create a slice of Champions League history – no side had ever turned around a four-goal first-leg deficit before.

2004: Deportivo La Coruna 4-0 Milan (5-4 agg)

Deportivo were among Spain's major forces just after the turn of the century and one of their finest moments in Europe came in April 2004 when, despite being 4-1 down from the first leg of their Champions League quarter-final with Milan, they stunned the Rossoneri at the Riazor.

Walter Pandiani, Juan Carlos Valeron and Albert Luque had Depor ahead on away goals before half-time, with veteran Fran Gonzalez scoring the fourth to make sure of their passage.

Depor were eliminated by eventual winners Porto in the semi-finals, but this comeback stood as arguably the very best in Champions League history until Barca went one better.

2000: Barcelona 5-1 Chelsea (aet, 6-4 agg)

Another time Barcelona overturned the odds.

A 3-1 first-leg loss at Stamford Bridge – having trailed 3-0 – had Barca in danger of being on the wrong end of a major Champions League upset prior to Chelsea's Roman Abramovich era, but in the return match the Catalan giants showed their true class.

Tore Andre Flo's 60th-minute goal was sending Chelsea through despite Rivaldo and Luis Figo scoring before the break, but Dani Garcia headed home in the 83rd-minute to force extra time.

Rivaldo atoned for an earlier missed penalty by converting from the spot after Celestine Babayaro was sent off and Patrick Kluivert finished the game off, crushing Chelsea's dreams.

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