Patrick Mahomes was left stunned after the Kansas City Chiefs fell to a 24-20 home loss against the Buffalo Bills on Sunday.

With time running out, Bills quarterback Josh Allen led his team on a brilliant 76-yard, 13-play drive, ending in a touchdown pass to tight-end Dawson Knox to give the visitors the lead with 1:04 left in the fourth quarter.

But Bills' hearts were in mouths as they feared a situation similar to January's Divisional-Round game, where Allen's touchdown pass to Gabe Davis with 13 seconds left on the clock looked to have sent Buffalo to the AFC Championship, only for Mahomes to set up a match-tying field goal before the Chiefs won in overtime.

However, Mahomes was not able to conjure up the same magic this time, throwing a crucial interception to cornerback Taron Johnson with 41 seconds remaining to seal victory for the Bills.

Mahomes was frustrated after the loss, telling reporters: "Every time I get the ball, no matter what the situation, is I expect to find a way to win.

"That's what this whole offense [and] this team expects. I always expect to win until there's literally no time so any time you lose definitely hurts. You lose a game, especially at home, it's never a good feeling.

"I thought we played some good football, we just made too many mistakes at the end of the day and when you make mistakes against another great football team you lose football games. It'll be good to learn from, but right now it stinks for sure."

Mahomes' killer pick to Johnson came as he tried to elude pressure from Bills' star edge rusher Von Miller, who signed a six-year $120million deal with Buffalo in March after winning the Super Bowl with the Los Angeles Rams the month prior.

Miller finished Sunday's game with two sacks, and Mahomes acknowledged his impact on the Bills' defense, saying: "Von [Miller] obviously made plays. 

"He's a Hall of Famer for a reason so he's going to make plays here and there. He's a great player so any time you add a great player like that, a Hall-of-Fame player, you have to account for him on every single play."

With the Chiefs and Bills both starting the season impressively, there is a decent chance the teams meet again in this season's AFC playoffs.

But Mahomes was keen to divert his team's focus to next weekend's clash with the San Francisco 49ers, who the Chiefs beat in the 2020 Super Bowl to give Mahomes his first Vince Lombardi trophy.

When asked whether he expects to play the Bills again in the postseason, the 27-year-old replied: "You can definitely see it because they're going to be a team that's going to be in the playoffs or competing for the playoffs.

"But you can't look ahead, and I think that's the biggest thing to me. I think I learned that last year in the AFC Championship game. Sometimes if you start looking ahead that's when you get beat and we don't want to look ahead.

"We have a great football team we're playing [the 49ers] and [then] we're going into the bye [week], and then we're going to have a schedule of a lot of division opponents coming up.

"So we want to make sure we focus on this next week - how can we get better to go out there, to go out there execute and try to find a way to win against a great football team at their home."

Aaron Rodgers believes the Green Bay Packers must find a way to keep matters simple after suffering a second straight defeat, though Matt LaFleur's assessment was blunter.

The Packers slipped to a 10-27 loss to the New York Jets on Sunday, a week on from Green Bay having a three-game winning streak ended by the New York Giants.

Those defeats leave Green Bay 3-3 for the season, with the Packers second in the NFC North, trailing the 5-1 Minnesota Vikings.

Quarterback Rodgers, the NFL's MVP for the last two seasons, believes the solution is to go back to basics.

"Simpler. Simplify some things," Rodgers, who was sacked four times against the Jets, told reporters. "All of it. I don't want to get too specific.

"I'm not attacking anything, I think based on how we've played the last two weeks it's going to be at our best interest to simplify things for everybody... the line, the backs, the receivers, especially with [Randall] Cobb's injury.

"Just need to simplify some things and maybe that will help us get back on track.

"[The offense was] very inconsistent. That's why I think we need to simplify things, because on a couple drives we didn't move the ball because it was very simple things.

"It was very simple plays, no motion. So we need to look at everything and the guys that we got and what we can accomplish with them and let's be smart about moving forward."

Coach LaFleur, however, did not hold back in his criticism of the Packers' offense, which has averaged 17.8 points per game through the opening six weeks of the season.

"That's about as frustrating of a game that I've ever been a part of from an offensive perspective," he said.

"We're in a pretty bad predicament right now."

For his part, Rodgers puts no blame onto the coaching staff.

"Nobody works harder than Matt on the plan each week, and nobody comes with better ideas than Matt and his staff," the 38-year-old added.

"If it's not working it's not because those guys aren't grinding, it's because we are not executing. If you think we have the right players, then we need to simplify things. If you don't, that's a whole other conversation."

Todd Bowles said any players "living off the Super Bowl are living in fantasy land" while Tom Brady told the Tampa Bay Buccaneers to "look in the mirror" after Sunday's loss to the Pittsburgh Steelers.

The Steelers had lost four straight games and were playing with a rookie quarterback in the form of Kenny Pickett but still earned a 20-18 win at Heinz Field.

For the Bucs it was a case of profligacy, with Tampa Bay scoring only once from four trips to the red zone. That was despite the Steelers lining up without three stop corners (Cam Sutton, Ahkello Witherspoon and Levi Wallace), outside linebacker T.J. Watt, and safety Minkah Fitzpatrick.

The Bucs were Super Bowl victors in the 2020 season before losing in the Divisional Round last year but head coach Bowles said some home truths after defeat in Pittsburgh.

"We didn't take them lightly, number one. Number two, I think guys that are living off the Super Bowl are living in a fantasy land," he said. 

"You've gotta get your hands dirty and go to work like everybody else. We've been working hard and we've gotta work harder. Nobody's gonna give us anything. Nobody's gonna feel sorry. 

"We've gotta go back as coaches, as players - the time for talking is over. You either gotta put up or shut up."

Asked for clarity on if anyone in the playing or coaching staff are living in "fantasy land", Bowles replied: "I didn't say we were. I'm just saying, you get patted on the back so much, you gotta relive -every year and every week, you've gotta go out there and earn your pay and earn your keep. 

"If you don't live like that, it's gonna be a result like today."

The loss saw a 12-game win streak against rookies snapped for Brady, who also failed to convert off a sneak for the first time as a Buccaneer at third-and-1 in the fourth quarter, having done so on 13 previous occasions.

"We didn't earn it," Brady said. "We didn't earn the win. It's a game of earning it and it's a game of playing well and performing well and we're just not doing a good job of that. 

"I don't think we've done it for six weeks. I think we're all playing less than what we're capable of. We've all gotta look at ourselves in the mirror and figure out why."

The Bucs remain top of the NFC South with a 3-3 record through six games.

Carolina Panthers interim coach Steve Wilks says "no one is bigger than the team" after he kicked Robbie Anderson out mid-game in their 24-10 loss to the Los Angeles Rams on Sunday.

The Panthers wide receiver was seen in a heated argument with position coach Joe Dailey late in the first half, before resuming their verbal exchange midway through the third quarter. Anderson had been benched for the third quarter and had been sitting alone on a cooler, before the second argument.

Wilks, who was taking charge for the first time after Matt Rhule was fired in midweek, intervened and sent Anderson to the locker room.

"No one is bigger than the team," Wilks told reporters. "I'm not going to focus and put a lot of attention on one individual… I'm not putting a lot of energy into one individual."

Anderson has been linked with a trade away from Carolina and Wilks said when asked about the 29-year-old's future: "Right now everybody is being evaluated, as well as myself.

"We've got to figure out what's going to be right chemistry to put out on the field, offensively and defensively."

Anderson proactively spoke to reporters after the game, stating he was "honestly confused" by the situation.

"I wanted to be in the game. I've never had somebody yell to get out of the game," Anderson said.

"I was honestly confused and upset by that. I should be. I don't see nobody that is a true competitor, that knows the value they bring and has true passion for the game, that will be okay with being told not to do something or being taken out of something when they didn't do nothing wrong."

Anderson failed to have a catch in Sunday's game, having entered the game with 13 receptions for 206 yards.

The former New York Jets receiver had signed a two-year $29.5 million extension through 2023 prior to last season, but only had 53 receptions for 519 yards in 2021.

"I wouldn't say I want to be traded," Anderson said. "I'm going to let God follow his plans for my life. I'll let things take his course on his time.

"I've been in trade rumours before. It's part of the game. I don't let it affect me."

The Philadelphia Eagles withstood the Dallas Cowboys' second-half charge to maintain their undefeated run to start the season with 26-17 victory at Lincoln Financial Field on Sunday.

The Eagles raced away to a 20-0 lead after 20 second-quarter points, before the Cowboys stormed back within three points when Cooper Rush found Jake Ferguson for a fourth-quarter TD.

But Jalen Hurts, who completed 15 of 25 attempts for 255 yards and rushed 27 yards on nine carries, added his second touchdown pass of the game for DeVonta Smith as the Eagles moved to a 6-0 start for the first time since 2004.

Cowboys QB Rush, starting for the injured Dak Prescott for the fifth straight game, threw three picks having previously gone 158 pass attempts without an interception. Rush finished making 18-of-38 for 181 yards with the one TD pass as the Cowboys moved to 4-2.

After a scoreless first quarter, Miles Sanders scored the Eagles' 13th rushing touchdown of the season, the most for a team league-wide through six games since 2005. Sanders finished the game with 18 carries for 71 yards.

From the next play, C.J. Gardner-Johnson intercepted Rush's pass, commencing the Eagles' drive for Hurts to lay off to A.J. Brown who crossed into the endzone after a nice step.

KaVontae Turpin's explosive kickoff run helped kicker Brett Maher get the Cowboys on the board prior to half-time, before Rush found Ferguson, allowing Ezekiel Elliott to score from the next play, capping a nine-play 79-yard drive.

The Cowboys had the momentum when Dante Fowler Jr sacked Hurts, with Rush finding Ferguson for a career-first TD in the last quarter to make it 20-17. But Hurts showed composure to lead a 13-play drive resulting in Smith's TD, before Gardner-Johnson picked another Rush pass intended for Ceedee Lamb.

The Buffalo Bills claimed a statement win as John Allen threw three touchdown passes as they improved to 5-1 with a 24-20 victory over the Kansas City Chiefs on Sunday.

Allen, who completed 27 of 40 attempts for 329 yards with no interceptions, found Dawson Knox for the game-winning touchdown with 1:04 left in the fourth quarter at Arrowhead Stadium.

The Bills sealed the win when Von Miller broke a double team to apply pressure on Chiefs QB Patrick Mahomes whose pass for Skyy Moore was picked by cornerback Taron Johnson with 0:41 remaining.

It ended a seesawing contest that had four lead changes, was tied at every change and was within one score throughout, with the AFC East-leading Bills moving ahead of the AFC West-leading Chiefs who fall to 4-2.

Mahomes made 25 of 40 attempts for 338 yards with two touchdowns and two interceptions, with Bills rookie Kaiir Elam picking off a redzone pass in the first quarter. Chiefs wide receiver Travis Kelce made franchise history by reaching the record for consecutive games with a reception (132), finishing with eight receptions for 108 yards but no TDs.

JuJu Smith-Schuster, who had five receptions for 113 yards, spun past two defenders after receiving a Mahomes pass for the opening TD, before Allen found Gabe Davis to reply before half-time, with Harrison Butker's franchise-record 62-yard field goal tying it up at half-time.

Stefon Diggs, who had 10 receptions for 148 yards, added his sixth receiving touchdown this season when Allen found him for 17-yard score but the Chiefs responded again as Mahomes punched a pass to Mecole Hardman.

Butker put the Chiefs up 20-17 in the fourth quarter, but Allen found Knox in the endzone to flip the script.

Rams respond as Anderson thrown out by Panthers

The Los Angeles Rams ground their way to a 24-10 victory over the Carolina Panthers to snap their two-game skid and move to 3-3.

Scores were locked at 10-10 with 16 seconds remaining in the third quarter when wide receiver Ben Skowronek swept down the outside and into the endzone for his career-first TD.

Matthew Stafford shook off the Rams' offensive issues to complete 26 of 33 passes for 253 yards and one touchdown for Allen Robinson, while Darrell Henderson rushed a fourth-quarter TD to pad the win.

Amid the Panthers' own offensive struggles, interim coach Steve Wilks threw Robbie Anderson out of the game after a heated argument with position coach Joe Dailey.

Bill Belichick celebrated his 324th career NFL win on Sunday as Bailey Zappe led the New England Patriots to a 38-15 victory at the Cleveland Browns.

This latest success moved Belichick into a tie for second for the most all-time coaching wins across the regular season and postseason.

The Patriots legend is now level with George Halas, trailing only Don Shula's 347.

The dominant defeat of the Browns was Belichick's 293rd regular season win, which has him third behind Halas (318) and Shula (328), while he leads all coaches with 31 playoff victories.

"I've got a ton of respect for coach Halas and the McCaskey family and what he did for professional football," Belichick said.

"The way that he and, since we're here, [first Browns coach] Paul Brown and others like them paved the way for us, as coaches, and paved the way for the National Football League to grow to what it is today. They laid down a lot of the building blocks."

Meanwhile, Zappe was as impressive in his second NFL start as he had been in his first, a 29-0 rout of the Detroit Lions last week.

The rookie fourth-rounder, who against the Lions became the fifth of five Patriot quarterbacks selected by Belichick outside the first round to win his first start, threw for 309 yards and two touchdowns in Cleveland, achieving a 118.4 passer rating.

Zappe is therefore the first rookie to win his first two career starts while recording a rating of at least 100 in both games since Hall of Famer Sonny Jurgensen in 1957.

Kenny Pickett could not finish his second NFL start after going into concussion protocol, but the Pittsburgh Steelers ensured their quarterback could celebrate an unlikely first win against the Tampa Bay Buccaneers.

Pickett – the first QB off the board in the 2022 NFL Draft – started for the first time in last week's big defeat to the Buffalo Bills.

But the rookie bounced back in some style against Tom Brady, securing a narrow lead before exiting the game midway through the third quarter. The Steelers protected that advantage to win 20-18.

Pickett had thrown his first career touchdown pass to Najee Harris on Pittsburgh's first drive.

A sloppy end to the first half allowed the Bucs to close the gap, but they headed in at halftime without having scored a TD – a first for a Brady team against the Steelers.

Pittsburgh lifted their game again following the restart, trading field goals before a hit on Pickett saw him leave the game, and was then ruled out.

Mitch Trubisky picked up the baton, though, connecting with Chase Claypool for another TD before Brady and Leonard Fournette belatedly responded.

A successful two-point conversion would have tied the game with time left for the Bucs to win it, but Brady's attempt was batted away, and Trubisky saw out only a second Steelers win of the year.

Another New York defeat for Packers on return to Lambeau

The Green Bay Packers gave up a home game to play in London for the first time in franchise history last week, losing to the New York Giants. And a return to Lambeau Field did little to lift Aaron Rodgers and Co., who fell to 3-3 with a 27-10 home loss to the New York Jets.

In fact, the Packers crowd appeared to turn on their team when a blocked punt gifted the Jets – now 3-0 on the road to start a season for the first time since 2010 – a two-TD lead their opponents could not recover from.

The Giants built on their upset of the Packers by doing the same to the Baltimore Ravens. They had trailed Green Bay 20-10 at halftime in Week 5 and were this time down by the same score in the fourth quarter, recovering for a 24-20 win to move to 5-1.

The Atlanta Falcons lost in Week 5 but also had momentum to carry into a matchup with the San Francisco 49ers after a 15-point fourth quarter against the Bucs. Following five straight games decided by seven points or fewer, the Falcons coasted to a 28-14 success.

Ryan extends Jags' miserable road run in AFC South

The Jacksonville Jaguars have not won a road game against an AFC South rival since 2017, a losing sequence of 13 games heading into Sunday's trip to the Indianapolis Colts.

It appeared as though Trevor Lawrence was to lead the Jags to a long-awaited win when the Colts trailed by a point at the Jacksonville 33 with just 23 seconds to play.

But Matt Ryan, having earlier passed Dan Marino (61,361) to climb to seventh all-time for passing yards, completed a pivotal TD pass to Alec Pierce to prolong the Jags' misery.

Washington Commanders quarterback Carson Wentz is facing a spell out of action after fracturing his finger, according to reports.

The Commanders beat the Chicago Bears 12-7 on Thursday to move 2-4 for the season, with Wentz playing the whole game. He was sacked three times and did not make a touchdown pass, throwing for just 99 yards.

However, on Saturday NFL media reported the 29-year-old – who was traded from the Indianapolis Colts ahead of the 2022 season – had suffered a fracture to the ring finger on his right hand.

Wentz, who had been suffering with a bicep issue before the game, played on with the fracture, despite being in clear pain, and will now see a specialist in Los Angeles to determine the next step in his treatment.

The injury comes after Commanders coach Ron Rivera hit back at suggestions he was not enthusiastic about the signing of Wentz.

Rivera said during his post-game news conference after the win over the Bears: "Everybody keeps wanting to say, I didn’t want anything to do with Carson.

"Well bull****. I'm the f****** guy that pulled out the sheets of paper, that looked at the analytics, that watched the tape when we were in Indianapolis.

"That's what p***** me off, because the young man doesn't deserve to have that all the time. I'm sorry, I'm done."

Rivera's outburst came after he had claimed a reason behind his team's poor start compared to the rest of the NFC East was at "quarterback", though he subsequently apologised and insisted he had not meant to disparage Wentz, who has thrown for 10 touchdowns this season.

Miami Dolphins quarterback Tua Tagovailoa has cleared the NFL's concussion protocol.

ESPN's Adam Schefter reported on Saturday that Tagovailoa had been cleared after sustaining a concussion in the Dolphins' Week 4 loss to the Cincinnati Bengals.

Tagovailoa will not play in Sunday's game against the Minnesota Vikings, in which third-string quarterback Skylar Thompson is expected to start. Thompson previously filled in for backup Teddy Bridgewater, who suffered a concussion on the first play of last Sunday's loss to the New York Jets.

However, Tagovailoa looks set to return for the Week 7 meeting with the Pittsburgh Steelers.

The Tagovailoa saga has led to a change in the NFL's concussion protocols, with the league and the NFLPA agreeing his return to play against the Buffalo Bills in Week 3 after an apparent head injury was "not what was intended when the protocols were drafted".

Tagovailoa was visibly unsteady on his feet after having his head slammed to the turf; however, he surprisingly returned for the second half.

He was flung to the turf in similar fashion by Bengals defensive lineman Josh Tupou and exhibited the fencing response, leading to him being taken from the field on a stretcher and transported to hospital.

Tagovailoa's response in the Bills game, known as ataxia, has now been added to the NFL's list of no-go symptoms. Bridgewater was ruled out against the Jets under this change.

A post on Twitter from Schefter read: "Since suffering a concussion in Week 4, Tua Tagovailoa, the Dolphins and his team of independent doctors followed a thorough process that far exceeded the NFL's concussion protocol, per sources.

"He received four outside opinions, in addition to team doctors, who unanimously cleared him from protocol and all agreed that his scans showed no signs of long-term impact on the brain."

Schefter also reported that Bridgewater has been cleared from the protocol and will serve as Thompson's backup against the Vikings.

With the Washington Commanders beating the Chicago Bears on Thursday, the NFC East improved to a league-leading 15-6 on the year.

The 2-4 Commanders are joined by three of the NFL's six teams with four wins or more, including the 5-0 Philadelphia Eagles – the only remaining unbeaten outfit.

Pre-season excitement centred on the AFC West and its potential to dominate the NFL, but the NFC East has instead surprisingly come to the fore, tallying five more wins through five weeks.

Of the six defeats for its four teams, three have been against division rivals.

There is therefore great anticipation for the fourth such matchup of the season on Sunday, when the Eagles play the Dallas Cowboys at Lincoln Financial Field.

With the Kansas City Chiefs also facing the Buffalo Bills, there is a compelling case to be made for fans this week getting to watch games between the best two teams in the NFC and the best two teams in the AFC.

Of course, the neutral may prefer to focus on the AFC tussle, where two of the leading quarterbacks in the sport will renew a rivalry last seen in their playoff epic.

But the supporting casts of the Eagles and the Cowboys might make them equally credible candidates as the league's best team come Monday.

It is certainly difficult to argue against the Eagles' start.

Their 5-0 record is their best since kicking off 7-0 in 2004; in fact, that was the last time any NFC East team won more than five games straight at the start of the year. The Eagles have already matched the 2009 New York Giants – the previous most recent example of a 5-0 start.

Outside the NFC East, such streaks have been far more commonplace. There has been at least one 5-0 team in every season since 2015, when there were six, including Super Bowl 50 champions the Denver Broncos.

That the 2015 Broncos were the last team to start 5-0 and then win the title suggests these stretches do not always mean a great deal in the long term, however.

Perhaps then the Eagles would be better served getting the first defeat out the way now, although that would mean losing control of this suddenly fiercely competitive division.

Either way, the Cowboys represent a far more serious threat than their opponents through Week 5.

The Eagles so far rank second in total offense – their 419.8 net yards per game topping the 2021 Cowboys' league-leading 407.0 – but have played defenses ranking 31st, 24th, 19th, ninth and 18th. The Dallas defense ranks seventh, and they have held each of their first five opponents to under 20 points for the first time since 1972.

As Stats Perform's efficiency versus expected model (EVE) ranks the Eagles' offense fourth and the Cowboys' defense fourth, it is clear where this game will be won and lost.

Previously, the Cowboys have had the tools to outgun their NFC East rivals. They have won their last three games against the Eagles by 20, 20 and 25 points – only once before (also versus the Eagles in the 1960s) winning four in a row by 20-plus points against any one team.

This time, with quarterback Dak Prescott still out, the Cowboys will instead focus on capitalising on the Eagles' own injury issues on their offensive line, where there are concerns around center Jason Kelce, tackle Jordan Mailata and guards Landon Dickerson and Isaac Seumalo.

Another big game from six-sack, second-year sensation Micah Parsons could be pivotal.

If the Eagles can negotiate that threat, though, a two-game lead even in this division might be enough to start planning for the playoffs now, given their schedule.

After the Cowboys, the Eagles have a bye week before playing teams ranking 32nd, 30th, 27th, 11th, 16th, 31st, 19th and 24th by overall EVE ahead of facing Dallas again in Week 16.

The NFC East's record winning start belongs to the 1991 Washington team, and the Eagles for now remain a way off the 11-0 sequence that preceded a Super Bowl triumph in a period of domination for this division.

But victory against the Cowboys would at least mean clearing the most significant hurdle in this young team's path.

Aaron Rodgers is off the Green Bay Packers injury report and expected to play on Sunday against the New York Giants although he may need to tape his right thumb.

Rodgers missed practice earlier in the week after injuring the thumb on his throwing hand on the final play of Sunday's 27-22 defeat to the New York Giants at Tottenham Hotspur Stadium.

The four-time NFL MVP was a full participant in practice on Thursday and Friday however, and the Packers removed him from their injury report on Friday.

"He threw the ball really well yesterday, so he's confident," Packers head coach Matt LaFleur told reporters on Friday.

The 38-year-old quarterback practiced with tape wrapped on his thumb on Friday, raising concerns it may impact his ability to make throws.

When asked if Rodgers will wear tape on the thumb in Sunday's game, LeFleur replied: "No idea."

Rodgers has made 114 of 168 attempts with a 67.9 per cent completion rate for 1157 yards and eight touchdowns with three interceptions this season.

The Packers, who are 3-2 and second in the NFC North, have ruled out rookie receiver Christian Watson and linebacker Tipa Galeai due to hamstring injuries.

Linebacker Rashan Gary, who has had five sacks this season, was listed as questionable on the injury report with a toe concern.

"It's the next man up and the standard doesn't change, but let's face it, the guy is pretty impactful I'd say when he's out on the grass," LaFleur said about Gary.

"Certainly he's a guy that we definitely want in there. When he's not in there I think you can feel the effects of that."

Andy Dalton is set to meet his former team the Cincinnati Bengals for a third successive season, and he could join a historic club.

Quarterback Dalton left the Bengals in 2020 after spending nine years with the team. He is Cincinnati's all-time passing touchdown leader (204).

The 34-year-old spent the 2020 season with the Dallas Cowboys before heading to Chicago and the Bears last year. He is now at the New Orleans Saints, and with Jameis Winston questionable due to back and ankle injuries, is expected to start in the Week 6 clash against his old team.

Having helped the Cowboys and the Bears to wins over the Bengals over the past two seasons, Dalton could become the fourth QB since 1950 to go 3-0 or better against the team he was drafted by.

Joe Burrow replaced Dalton in Cincinnati and was the key to their charge to the Super Bowl last season.

Burrow has completed at least 60 per cent of his passes in 22 successive regular-season games, which ties him level with Steve Young for the second-longest streak in NFL history behind Drew Brees, who went 31 straight between 2018 and 2020.

The Bengals are 4-2 all-time on the road against the Saints, their second-best road record against a single opponent, yet in Taysom Hill they face a player who made history last week. 

In New Orleans' 39-32 win over the Seattle Seahawks, Hill became the first player in the league to rush for 100+ yards on 10+ yards per carry, rush for three or more touchdowns and also throw a TD pass in the same game.

Cam Akers will miss the Los Angeles Rams' Week 6 clash against the Carolina Panthers for personal reasons.

Rams coach Sean McVay revealed running back Akers will play no part when the Panthers visit SoFi Stadium on Sunday.

McKay stated that the situation is "uncharted territory" for Akers and the Rams (2-3) amid reports he could be traded.

Asked about Akers' future with Los Angeles, he replied: "We're working through some different things right now, so hopefully you guys understand and respect that."

Akers missed the majority of last season due to an Achilles injury.

The 23-year-old has made only 151 yards from 51 carries in five games in 2022, scoring just one touchdown. 

McKay will be looking for a big contribution from Darrell Henderson in the absence of Akers this weekend, while Malcolm Brown is also on the active roster. 

The Dallas Cowboys have listed quarterback Dak Prescott as questionable for Sunday's meeting with the Philadelphia Eagles.

Prescott has not featured since Week 1 due to a thumb injury, and Cowboys coach Mike McCarthy told the press earlier this week that the 29-year-old was unlikely to be fit to return in Week 6.

However, Dallas have not yet ruled their QB out of contention, instead listing Prescott as questionable for the game in Philadelphia.

Cooper Rush, though, is still expected to start, with the stand-in QB having led the Cowboys to four successive wins in Prescott's absence.

Rush is the third QB in NFL history, since statistics were first tracked in 1950, to win on his first five career starts while throwing no more than one interception over that span, after Kyle Allen and Patrick Mahomes.

The Cowboys head into the game with recent history on their side, having won their past three meetings with the Eagles by 20, 20 and 25 points. The last time any NFL team had four straight 20-point wins against an opponent was the Colts against the Jaguars from 2013-14.

Philadelphia are the NFL's only unbeaten team, however, and are the first side in league history to win their opening five games of a season while averaging 400+ yards of offense and not losing a single fumble.