Marco Silva conceded Fulham "cannot switch off for one second" in the Premier League, after Danny Ings' last-gasp equaliser denied the Cottagers all three points against West Ham.
The hosts appeared on course to take the spoils in the London derby at Craven Cottage, where Raul Jimenez put them in front after 24 minutes.
However, the visitors snatched a dramatic equaliser in the fifth minute of stoppage time, when substitute Ings fired past Fulham goalkeeper Bernd Leno.
And Silva acknowledged his side's brief lapse in concentration proved costly.
"It just shows that in this Premier League, you cannot switch off for one second," he told BBC Sport. "We are aware of the quick throws, and we have to keep focus and concentration.
"A big frustration for us because, before that, it was a good performance. It was clear we were the best team on the pitch. They did not have one shot [on target] in the first half.
"We should have won this game. It was not a game where West Ham pushed us back. The goal came after we switched off. It just shows you have to keep focus until the last second."
Silva also felt Fulham should have been awarded a first-half penalty when Adama Traore was challenged by Max Kilman.
"It was a clear, clear, penalty in my opinion," he added. "It's difficult to understand why it was not a penalty in that situation. I don't even want to say anything more about it."
Meanwhile, West Ham boss paid tribute to Ings, who was making only his second Premier League appearance of the season - with both coming as a late substitute.
"It was a very 'Danny Ings' goal!", Lopetegui told West Ham's official website. "He is always agile in those kinds of actions, and he took his chance very well.
"I'm really happy for him, because he hasn't played much up until now, but he is always ready to go. He is a really good example to all of his team-mates, and it's great to see his work pay off.
"As a player, it can be hard when you don't know when the coach is going to call you. The important thing is to try and always be ready, because you are going to be needed at some point.
"Scoring in the last minute today is important, because he's shown everyone that you have to believe until the end. Even though there were things we could do better today, we kept going, and we got something out of the game."
Arsenal 'always find a way' – Arteta
Mikel Arteta showered praise on his Arsenal players after their 3-1 victory against Southampton, saying his squad will "always find a way" to win.
The Gunners bounced back from Cameron Archer's opener to earn their 400th Premier League home win on Saturday, with Kai Havertz, Gabriel Martinelli and Bukayo Saka on target.
Arsenal enter the international break in third, hot on the heels of leaders Liverpool and level on points with Manchester City.
They also continued their impressive record against Southampton, extending their unbeaten run against them in the top flight to 25 matches (W17 D8), but the hosts were made to work for the win.
Arteta's side registered 14 shots in the first half with an expected goals (xG) total of 1.15, though their only shot on target came in stoppage time courtesy of Thomas Partey.
The introduction of Martinelli, Leandro Trossard and Mikel Merino prompted an improvement in attack shortly after Havertz's leveller.
"The start was exceptional, the dominance, the chances. It was unbelievable not to go one, two, three goals up," Arteta said.
"We conceded the goal, and then it was game on.
"I thought the team reacted with a lot of authority, and I am happy the team can react like this - but not happy after the chances we had that we had to go through that.
"The substitutes changed the energy and also the feel in the crowd. We won in the end and I think we deserved it. This team always finds a way.
"The way we started was phenomenal, but we didn't get our reward. We had a difficult context at 1-0 but we did it."
Arteta also lauded Saka's performance after the England international took his goal involvement tally to nine for the season with his strike coming after two assists.
This campaign, only Erling Haaland and Cole Palmer (10 each) have been involved in more goals than Saka.
The 23-year-old has also taken on the role of captain in Martin Odegaard's absence, something Arteta believes Saka is embracing.
"For sure. That's the maturity and steps players have to do. He's been in the team long enough to earn the right to have that role. He believes in that," Arteta said.
"He has the capacity to change and decide games like many other players. If we want to be at the top, sometimes players have to create those moments, and he's certainly done that again today."
Southampton, meanwhile, are now without a win in their last 20 Premier League matches, equalling their longest top-flight winless run (a run of 20 between August and December in 1969).
But they had their moments to level the contest, with Tyler Dibling's deflected effort and Taylor Harwood-Bellis' header striking the woodwork prior to Saka's settler.
"I feel so much more positive and proud of my team than I did on Monday [after a 3-0 defeat at Bournemouth], and we played against one of the best teams in the country," Russell Martin told BBC Sport.
"If we play like that in the next block of games, I'd be very happy. I think we're learning and growing, and we're on a journey. But we're doing it under huge scrutiny and the intensity of the Premier League.
"I have to keep the guys on track and on path. There's a lot to be frustrated about, we don't have enough points on the board and a win yet, but I loved all of our resilience."
Lopetegui praises West Ham's 'strong mentality' after first home win
Julen Lopetegui had plenty of praise for West Ham's "strong mentality" as his side triumphed 4-1 against Ipswich Town at London Stadium.
It marked the Hammers’ first win at home this Premier League season, while Ipswich remain winless.
The hosts went 1-0 ahead after 48 seconds through Michail Antonio - West Ham’s earliest Premier League goal on record.
Having been pegged back to level terms just five minutes later when Liam Delap scored following a corner, Lopetegui was pleased with how his side set about regaining control, with Mohammed Kudus, Jarrod Bowen and Lucas Paqueta on target.
"We started better but we suffered a very early goal too. We conceded from the first corner and maybe we could have done better. It was key as the team then showed a strong mentality," he said, as quoted by Sky Sports.
"In the bad moments, you have to be strong. We did against Brentford and we did again today. It's important to highlight as it will help us become a better team."
West Ham proved the dominant force, registering 23 shots with 17 of them coming from inside the box. It meant Lopetegui’s men accumulated an expected goals (xG) total of 3.17 by full-time.
"We're happy when we win. We work for this. We're happy for the fans as they deserve this and for the players as they are working very hard. It was against a good team. They didn't lose to Villa, Fulham, Southampton, Brighton so it's a good win,” he added.
For Lopetegui's counterpart Kieran McKenna, the result was another stark reminder of the challenges the Premier League presents for a promoted side.
The Tractor Boys sit in seventeenth, just one point above the relegation zone.
"It ended up a disappointing day for us. There was a large majority of the first half in which it was a competitive game that was evenly fought. We played some good football but we conceded poor goals which changed the momentum of the game," McKenna said.
"We didn't deal well enough with the direct play. The goals came from those moments so there's a lot for us to learn."
Ipswich allowed their opponents 28 touches inside their box, while they were reliant on the woodwork to stop West Ham from adding to their lead.
"They didn't have to work hard for their goals. Apart from the fourth, the goals came too easily. They have quality and they showed that with the goals and chances they created if you give them opportunities," reflected McKenna.
Michel craving bolder approach to halt Girona losing streak
Girona head coach Michel has urged his team to rediscover their attacking spark by adopting a bolder approach in the final third against Athletic Bilbao this Sunday.
Girona return to LaLiga action at the Estadi Montilivi following their 3-2 Champions League defeat to Feyenoord in midweek, leaving them winless in the competition.
The Blanquivermells have also struggled in the league, failing to win any of their last four matches (D2 L2), while only scoring two goals during that run.
Michel's side currently sit 13th in the standings with nine points from their first eight games, while Bilbao are up in sixth on 14 points.
Girona have lost only one of their last four against this weekend's opponents in LaLiga (W2 D1), with Michel desperate to see his side return to winning ways.
"The most important thing is the league, which is our vitality, it is where we have to perform to be able to make the club grow," Michel said.
"We need a victory with home fans so that the good feelings can turn into points."
But the Girona head coach did take on some of the blame for his side's transition to playing Champions League football this term.
After tomorrow's fixture, the Blanquivermells will have played six games in 18 days, and Michel was able to pinpoint the differences from last season to this.
"I have to be the one who adapts to the player's characteristics because otherwise they won't be comfortable on the pitch," Michel said.
"In my mind it is clear that my way of playing is good for any player, but they have to understand that they have to take a step in our game. Any player can do that.
"I'm not asking them to dribble past three defenders and score, but I do ask that they play forward and upward, that they should always look at their opponents' faces (bravely).
"We have a team that can perform very well and do things very well. We must not enter into negative dynamics."
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